Trial Condition(s):
A Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of a Nasal Spray in Allergen Induced Seasonal Allergic Rhinitis (GEYSER)
12962
Not Available
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Finding out how fast azelastine nasal spray works in subjects with hay fever.
- History of seasonal allergic rhinitis to ragweed pollen for last 2 consecutive seasons; - Positive response to skin prick test to ragweed allergen at screening; - Be willing to participate in the trial.
- History of hypersensitivity to azelastine; - Females who are pregnant or lactating; - Relative chronic sinusitis or nasal structural abnormalities causing greater than 50% obstruction; - Asthma that requires other than occasional use of inhaled short-acting beta-2 antagonist; - Known non-responsiveness to antihistamines; - Alcoholism or drug abuse within 2 yrs. of screening; - Current or regular use within 6 months of any type of tobacco product; - Evidence of any clinically significant hematological, renal, endocrine, pulmonary, gastrointestinal, cardiovascular, hepatic, psychiatric, neurologic or malignancies within the last 5 years; - History of a positive test to HIV, TB, hepatitis B or C.
Locations | |
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Locations Kingston General Hospital Kingston, Canada, K7L 2V7 | Contact Us: E-mail: [email protected] Phone: Not Available |
A Four-Way Double-Blind, Randomized, Placebo Controlled Study to Determine the Efficacy and Speed of Azelastine Nasal Spray and Antihistaminic Agents in Adult Subjects with Allergen Induced Seasonal Allergic Rhinitis
Trial Type:
Interventional
Intervention Type:
Drug
Trial Purpose:
Treatment
Allocation:
Randomized
Blinding:
Double Blind
Assignment:
Crossover Assignment
Trial Arms:
4