Prostatic Hypertrophy, Benign

Inclusion Criteria

- Men with benign prostate hypertrophy requiring surgical treatment
 - Age up to 80 years
 - Documented, dated, written Informed Consent
 - Anesthesiologists agreement with swallowing 1 tablet one hour prior surgery

Exclusion Criteria

- Any unstable medical, psychiatric, or substance abuse disorder
 - History of previous prostatectomy
 - Patients suspect of prostate cancer
 - Hereditary degenerative retinal disorder
 - History of previous Non-arteric Anterior Ischemic Optic Neuropathy (NAION) episode or unilateral vision impairment
 - Any cardiovascular condition
 - History of myocardial infarction, stroke or life-threatening arrhythmia within the prior 6 months
 - Uncontrolled atrial fibrillation/flutter at screening
 - Severe chronic or acute liver disease
 - Chronic hematological disease which may lead to priapism
 - Bleeding disorder
 - Significant active peptic ulceration
 - Resting hypotension
 - History of positive test for Hepatitis B surface antigen or Hepatitis C
 - Symptomatic postural hypotension within 6 months of Visit 1
 - Patients who subjectively or in the opinion of the investigator did not tolerate the initial dose of study medication well
 - Subjects who are taking nitrates or nitric oxide donors
 - Subjects who are taking androgens or anti-androgens
 - Subjects who are taking potent inhibitors of cytochrome P4503A4
 - Subjects who have received any investigational drug within 30 days of Visit 1
 - Using of alpha-blockers during two days prior to first dosing of study medication and after ablation of prostate
 - Use of inhibitors of 5-alpha reductase after ablation of prostate
 - Subjects with serum creatinine clearance <30.0 mL/min
 - Elevation of Aspartate aminotransferase (AST) and/or Alanine aminotransferase (ALT) >3 times the upper limit of normal
 - Subjects with known hypersensitivity to Vardenafil
 - Subjects who are illiterate or unable to understand subject diaries
 - Subjects who would be non-compliant with the study visit schedule