Trial Condition(s):

Colorectal Cancer, Cardiovascular Disease, Bleeding

Study to develop a prediction model to understand the effect of low-dose Aspirin on cancer that develops in the colon and/or the rectum, diseases that affects the heart or blood vessels and safety outcomes in European countries. The study is also called PEACOS model EU (PEACOCS)

Bayer Identifier:

20751

ClinicalTrials.gov Identifier:

NCT03904732

EudraCT Number:

Not Available

Study Completed

Trial Purpose

In this study researchers want to learn more about the effect of low-dose Aspirin on cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the large intestine before the anus), diseases that affects the heart or blood vessels and safety outcomes. Study will focus on two groups of adults aged 50-59 and 60-69 years having an increased risk of heart and/or blood vessel disease who are taking either low-dose aspirin or no low-dose aspirin for heart and/or blood vessel disease prevention. The model will be based on information publicly available either on government organization websites or in scientific journals. Based on these data researchers will focus in a first step to build a model of 2 million adults (1 million for each age group) for the UK population and in a second step, the model will be modified for use with other European countries, to reflect the epidemiology and guidelines for aspirin use in these countries.

Inclusion Criteria
- European populations (UK and other European countries) of adults aged 50-59 and 60-69 years eligible for using aspirin for primary or secondary CVD prevention. Subjects are eligible when they have no contra-indications, and are at increased risk of CVD (primary prevention) or have suffered from a previous CVD event
Exclusion Criteria
- None

Trial Summary

Enrollment Goal
2000000
Trial Dates
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Phase
N/A
Could I receive a placebo?
No
Products
Aspirin (Acetylsalicylic Acid, BAYE4465)
Accepts Healthy Volunteers
No

Where to Participate

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Locations
Status
LocationsStatus
Locations

Mimicked Population

Mimicked Population, United Kingdom

Status
Completed
 

Trial Design