Trial Condition(s):

Non-valvular Atrial fibrillation (NVAF)

A study to evaluate the safety and effectiveness of Rivaroxaban (Xarelto) for prevention of stroke and systemic embolism in Indian patients with Non-valvular Atrial Fibrillation (NVAF) (XARIN)

Bayer Identifier:

20387 Identifier:


EudraCT Number:

Not Available

EU CT Number:

Not Available

Recruitment Complete

Trial Purpose

This study is planned to collect prospective data and evaluate the safety and effectiveness of rivaroxaban for the prevention of stroke and systemic embolism in Indian patients with NVAF when used in clinical practice under real-life conditions.
The study will be conducted in routine clinical practice settings.
Approximately 1000 patients from India will be enrolled in this study. Patients will be observed for maximum period of 12 months after the start of Xarelto treatment or until it is no longer possible (e.g. lost to follow-up, death, withdrawal) before the end of the observation period.
The decision by the investigator to start with of Xarelto must be independent of the inclusion of a patient to the study.

Inclusion Criteria
- Patient should be an adult female or male, ≥18 years of age;
- Patient should be diagnosed with NVAF and initiated with rivaroxaban treatment for prevention of stroke or systemic embolism per investigator’s routine treatment practice;
- Patient should not have received rivaroxaban in the past; 
- Patient/patient’s legally acceptable representative should be willing to provide written informed consent.
Exclusion Criteria
- Patient has contraindications to receive rivaroxaban therapy according to local prescribing information;
- Patient is receiving anticoagulant therapy for indication other than NVAF and that needs to be continued as per discretion of treating physician;
- Patient is participating in an investigational program with interventions outside of routine clinical practice.

Trial Summary

Enrollment Goal
Trial Dates
Could I receive a placebo?
Xarelto (Rivaroxaban, BAY59-7939)
Accepts Healthy Volunteers

Where to Participate


Sunshine Hospital

Secunderabad, India, 500003

Trial Design