Trial Condition(s):

Peripheral Artery Disease

Efficacy and safety of rivaroxaban in reducing the risk of major thrombotic vascular events in subjects with symptomatic peripheral artery disease undergoing peripheral revascularization procedures of the lower extremities (VOYAGER PAD)

Bayer Identifier:

17454

ClinicalTrials.gov Identifier:

NCT02504216

EudraCT Number:

2014-005569-58

Study Completed

Trial Purpose

The purpose of study was to test whether rivaroxaban added to standard of care treatment, when compared to placebo, had the potential to reduce the incidence of the clinical events related to the clots and complications of the heart and brain (CV death, MI, or stroke) or the legs (acute limb ischemia or major amputation) in patients who had undergone recent procedure(s) to improve the blood flow of their legs.

Inclusion Criteria
- Age ≥50
 - Documented moderate to severe symptomatic lower extremity atherosclerotic peripheral artery disease
 - Technically successful peripheral revascularization distal to the external iliac artery for symptomatic PAD (Peripheral artery disease) within the last 10 days prior to randomization
Exclusion Criteria
- Patients undergoing revascularization for asymptomatic PAD or mild claudication without functional limitation of the index leg.
- Patients undergoing revascularization of the index leg to treat an asymptomatic or minimally symptomatic restenosis of a bypass graft or target lesion restenosis.
- Prior revascularization on the index leg within 10 days of the qualifying revascularization.
- Planned dual antiplatelet therapy (DAPT) use for the qualifying revascularization procedure of clopidogrel in addition to Acetylic salicylic acid (ASA) for >6 months after the qualifying revascularization procedure; it is strongly recommended that any course of clopidogrel is kept to the minimum necessary in accordance with local standard of care and international practice guidelines (typically 30 days, or up to 60 days  for some drug-coated products or devices) and is only allowed for up to 6 months for complex procedures or devices in the investigator’s opinion that require longer use. 
- Planned use of any additional antiplatelet agent other than clopidogrel and ASA after the qualifying revascularization procedure.

Trial Summary

Enrollment Goal
6564
Trial Dates
black-arrow
Phase
3
Could I receive a placebo?
Yes
Products
Xarelto (Rivaroxaban, BAY59-7939)
Accepts Healthy Volunteers
No

Where to Participate

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Locations
Status
LocationsStatus
Locations

Investigative Site

Shreveport, United States, 71103

Status
Completed
 
Locations

Investigative Site

Wellington, United States, 33449

Status
Completed
 
Locations

Investigative Site

Winston-Salem, United States, 27103

Status
Completed
 
Locations

Investigative Site

Muskegon, United States, 49444

Status
Completed
 
Locations

Investigative Site

Lansing, United States, 48912

Status
Completed
 
Locations

Investigative Site

Saint Louis, United States, 63128

Status
Completed
 
Locations

Investigative Site

Northridge, United States, 91325

Status
Completed
 
Locations

Investigative Site

Roseville, United States, 95661

Status
Completed
 
Locations

Investigative Site

Camp Hill, United States, 17011

Status
Completed
 
Locations

Investigative Site

San Antonio, United States, 78258

Status
Completed
 
Locations

Investigative Site

Tupelo, United States, 38801

Status
Completed
 
Locations

Investigative Site

Kingwood, United States, 77339

Status
Completed
 
Locations

Investigative Site

Birmingham, United States, 35294-0012

Status
Completed
 
Locations

Investigative Site

Fort Wayne, United States, 46804

Status
Completed
 
Locations

Investigative Site

Glendale, United States, 85340

Status
Completed
 
Locations

Investigative Site

Alexandria, United States, 71301

Status
Completed
 
Locations

Investigative Site

Arlington Heights, United States, 60005

Status
Completed
 
Locations

Investigative Site

Pensacola, United States, 32501

Status
Completed
 
Locations

Investigative Site

Clearwater, United States, 33756

Status
Completed
 
Locations

Investigative Site

Teaneck, United States, 07666

Status
Completed
 
Locations

Investigative Site

Madison, United States, 53713

Status
Completed
 
Locations

Investigative Site

Saratoga Springs, United States, 12866

Status
Completed
 
Locations

Investigative Site

Atlantis, United States, 33462

Status
Completed
 
Locations

Investigative Site

Hillsboro, United States, 97123

Status
Completed
 
Locations

Investigative Site

Tallahassee, United States, 32308

Status
Completed
 
Locations

Investigative Site

Huntsville, United States, 77340

Status
Completed
 
Locations

Investigative Site

Torrance, United States, 90502

Status
Completed
 
Locations

Investigative Site

Springfield, United States, 62701

Status
Completed
 
Locations

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Wausau, United States, 54401

Status
Completed
 
Locations

Investigative Site

Lincoln, United States, 68506

Status
Completed
 
Locations

Investigative Site

Mission Viejo, United States, 92691

Status
Completed
 
Locations

Investigative Site

Manitowoc, United States, 54220

Status
Completed
 
Locations

Investigative Site

Gainesville, United States, 32605

Status
Completed
 
Locations

Investigative Site

Lewiston, United States, 04240

Status
Completed
 
Locations

Investigative Site

Durham, United States, 27710

Status
Completed
 
Locations

Investigative Site

Jacksonville, United States, 32216

Status
Completed
 
Locations

Investigative Site

Knoxville, United States, 37934

Status
Completed
 
Locations

Investigative Site

Bay City, United States, 48708

Status
Completed
 
Locations

Investigative Site

Ocala, United States, 34474

Status
Completed
 
Locations

Investigative Site

Greenville, United States, 29657

Status
Completed
 
Locations

Investigative Site

Philadelphia, United States, 19104

Status
Completed
 
Locations

Investigative Site

Erie, United States, 16507

Status
Completed
 
Locations

Investigative Site

Toledo, United States, 43614

Status
Completed
 
Locations

Investigative Site

Cincinnati, United States, 45219

Status
Completed
 
Locations

Investigative Site

Springfield, United States, 45505

Status
Completed
 
Locations

Investigative Site

Flemington, United States, 08822

Status
Completed
 
Locations

Investigative Site

Lebanon, United States, 03756-1000

Status
Completed
 
Locations

Investigative Site

Chapel Hill, United States, 27517

Status
Completed
 
Locations

Investigative Site

Dearborn, United States, 48126

Status
Completed
 
Locations

Investigative Site

Detroit, United States, 48201

Status
Completed
 
Locations

Investigative Site

Dallas, United States, 75216-7167

Status
Completed
 
Locations

Investigative Site

Barcelona, Spain, 08036

Status
Completed
 
Locations

Investigative Site

L'Hospitalet de Llobregat, Spain, 08907

Status
Completed
 
Locations

Investigative Site

Tarragona, Spain, 43005

Status
Completed
 
Locations

Investigative Site

Ciudad Real, Spain, 13005

Status
Completed
 
Locations

Investigative Site

Graz, Austria, 8036

Status
Completed
 
Locations

Investigative Site

Wien, Austria, 1140

Status
Completed
 
Locations

Investigative Site

Baltimore, United States, 21201-1595

Status
Completed
 
Locations

Investigative Site

Baltimore, United States, 21218

Status
Completed
 
Locations

Investigative Site

Merrillville, United States, 46410

Status
Completed
 
Locations

Investigative Site

Miami, United States, 33173

Status
Completed
 
Locations

Investigative Site

Daytona Beach, United States, 32117

Status
Completed
 
Locations

Investigative Site

Washington, United States, 20422

Status
Completed
 
Locations

Investigative Site

Washington, United States, 20007

Status
Completed
 
Locations

Investigative Site

Iowa City, United States, 52242

Status
Completed
 
Locations

Investigative Site

Urbana, United States, 61801

Status
Completed
 
Locations

Investigative Site

Springfield, United States, 65807

Status
Completed
 
Locations

Investigative Site

Victoria, United States, 77901

Status
Completed
 
Locations

Investigative Site

Austin, United States, 78705

Status
Completed
 
Locations

Investigative Site

Humble, United States, 77338

Status
Completed
 
Locations

Investigative Site

Rapid City, United States, 57702

Status
Completed
 
Locations

Investigative Site

Torino, Italy, 10126

Status
Completed
 
Locations

Investigative Site

Macerata, Italy, 62100

Status
Completed
 
Locations

Investigative Site

Perugia, Italy, 06132

Status
Completed
 
Locations

Investigative Site

Oklahoma City, United States, 73135

Status
Completed
 
Locations

Investigative Site

Minot, United States, 58701

Status
Completed
 
Locations

Investigative Site

St. Louis, United States, 63128

Status
Completed
 
Locations

Investigative Site

Coon Rapids, United States, 55433

Status
Completed
 
Locations

Investigative Site

St. Cloud, United States, 56303

Status
Completed
 
Locations

Investigative Site

Alexander City, United States, 35010

Status
Completed
 
Locations

Investigative Site

Huntsville, United States, 35801-4317

Status
Completed
 
Locations

Investigative Site

Houston, United States, 77030

Status
Completed
 
Locations

Investigative Site

Palo Alto, United States, 94304

Status
Completed
 
Locations

Investigative Site

Stanford, United States, 94305

Status
Completed
 
Locations

Investigative Site

Hamilton, Canada, L8L 2X2

Status
Completed
 
Locations

Investigative Site

Winnipeg, Canada, R2H 2A6

Status
Completed
 
Locations

Investigative Site

Leipzig, Germany, 04103

Status
Completed
 
Locations

Investigative Site

Kaiserslautern, Germany, 67657

Status
Completed
 
Locations

Investigative Site

Münster, Germany, 48149

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 10787

Status
Completed
 
Locations

Investigative Site

Bad Krozingen, Germany, 79189

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01099

Status
Completed
 
Locations

Investigative Site

Frankfurt, Germany, 65929

Status
Completed
 
Locations

Investigative Site

GENT, Belgium, 9000

Status
Completed
 
Locations

Investigative Site

GENK, Belgium, 3600

Status
Completed
 
Locations

Investigative Site

Springfield, United States, 62702

Status
Completed
 
Locations

Investigative Site

Minato-ku, Japan, 108-8329

Status
Completed
 
Locations

Investigative Site

Kitakyushu, Japan, 802-8555

Status
Completed
 
Locations

Investigative Site

Shibukawa, Japan, 377-0061

Status
Completed
 
Locations

Investigative Site

Kurume, Japan, 830-8577

Status
Completed
 
Locations

Investigative Site

Himeji, Japan, 671-1227

Status
Completed
 
Locations

Investigative Site

Matsuyama, Japan, 790-8524

Status
Completed
 
Locations

Investigative Site

Asahikwa, Japan, 078-8510

Status
Completed
 
Locations

Investigative Site

Hatsukaichi, Japan, 738-8503

Status
Completed
 
Locations

Investigative Site

Bydgoszcz, Poland, 85-094

Status
Completed
 
Locations

Investigative Site

Bunkyo-ku, Japan, 113-8519

Status
Completed
 
Locations

Investigative Site

Bologna, Italy, 40138

Status
Completed
 
Locations

Investigative Site

Firenze, Italy, 50134

Status
Completed
 
Locations

Investigative Site

Potenza, Italy, 85100

Status
Completed
 
Locations

Investigative Site

Coronel Suarez, Argentina, B7540GHD

Status
Completed
 
Locations

Investigative Site

Mar del Plata, Argentina, 7600

Status
Completed
 
Locations

Investigative Site

Rosario, Argentina, S2000QID

Status
Completed
 
Locations

Investigative Site

Buenos Aires, Argentina, C1428ART

Status
Completed
 
Locations

Investigative Site

Buenos Aires, Argentina, C1119ACN

Status
Completed
 
Locations

Investigative Site

München, Germany, 80331

Status
Completed
 
Locations

Investigative Site

Darmstadt, Germany, 64276

Status
Completed
 
Locations

Investigative Site

Karlsbad, Germany, 76307

Status
Completed
 
Locations

Investigative Site

Mainz, Germany, 55131

Status
Completed
 
Locations

Investigative Site

Heidelberg, Germany, 69129

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01067

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 20246

Status
Completed
 
Locations

Investigative Site

München, Germany, 81675

Status
Completed
 
Locations

Investigative Site

München, Germany, 80336

Status
Completed
 
Locations

Investigative Site

Krefeld, Germany, 47805

Status
Completed
 
Locations

Investigative Site

Karlsruhe, Germany, 76133

Status
Completed
 
Locations

Investigative Site

Rosenheim, Germany, 83022

Status
Completed
 
Locations

Investigative Site

Sonneberg, Germany, 96515

Status
Completed
 
Locations

Investigative Site

Bern, Switzerland, 3010

Status
Completed
 
Locations

Investigative Site

Luzern, Switzerland, 6000

Status
Completed
 
Locations

Investigative Site

St. John's, Canada, A1C 2H6

Status
Completed
 
Locations

Investigative Site

Quebec, Canada, G1L 3L5

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 01-211

Status
Completed
 
Locations

Investigative Site

Szczecin, Poland, 70-111

Status
Completed
 
Locations

Investigative Site

Bialystok, Poland, 15_111

Status
Completed
 
Locations

Investigative Site

Hodonin, Czech Republic, 69501

Status
Completed
 
Locations

Investigative Site

Hradec kralove, Czech Republic, 500 05

Status
Completed
 
Locations

Investigative Site

Vratimov, Czech Republic, 73932

Status
Completed
 
Locations

Investigative Site

Olomouc, Czech Republic, 775 20

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 01-868

Status
Completed
 
Locations

Investigative Site

Sapporo, Japan, 060-0031

Status
Completed
 
Locations

Investigative Site

Gifu, Japan, 500-8717

Status
Completed
 
Locations

Investigative Site

Kladno, Czech Republic, 27259

Status
Completed
 
Locations

Investigative Site

Plzen, Czech Republic, 30599

Status
Completed
 
Locations

Investigative Site

København Ø, Denmark, 2100

Status
Completed
 
Locations

Investigative Site

Aarhus N, Denmark, 8200

Status
Completed
 
Locations

Investigative Site

Viborg, Denmark, 8800

Status
Completed
 
Locations

Investigative Site

Kolding, Denmark, 6000

Status
Completed
 
Locations

Investigative Site

Odense C, Denmark, 5000

Status
Completed
 
Locations

Investigative Site

Miskolc, Hungary, 3526

Status
Completed
 
Locations

Investigative Site

Budapest, Hungary, 1115

Status
Completed
 
Locations

Investigative Site

Kistarcsa, Hungary, 2143

Status
Completed
 
Locations

Investigative Site

Kaposvar, Hungary, 7400

Status
Completed
 
Locations

Investigative Site

Shizuoka, Japan, 420-8630

Status
Completed
 
Locations

Investigative Site

Pecs, Hungary, 7624

Status
Completed
 
Locations

Investigative Site

Budapest, Hungary, 1085

Status
Completed
 
Locations

Investigative Site

Sabadell, Spain, 08208

Status
Completed
 
Locations

Investigative Site

Brno, Czech Republic, 656 91

Status
Completed
 
Locations

Investigative Site

Praha 10, Czech Republic, 10100

Status
Completed
 
Locations

Investigative Site

A Coruña, Spain, 15006

Status
Completed
 
Locations

Investigative Site

Kobe, Japan, 651-0053

Status
Completed
 
Locations

Investigative Site

Itabashi-ku, Japan, 173-0015

Status
Completed
 
Locations

Investigative Site

Himeji, Japan, 670-0981

Status
Completed
 
Locations

Investigative Site

Bad Friedrichshall, Germany, 74177

Status
Completed
 
Locations

Investigative Site

Bremen, Germany, 28277

Status
Completed
 
Locations

Investigative Site

Erlangen, Germany, 91054

Status
Completed
 
Locations

Investigative Site

Frankfurt, Germany, 60596

Status
Completed
 
Locations

Investigative Site

Bad Nauheim, Germany, 61231

Status
Completed
 
Locations

Investigative Site

Lübeck, Germany, 23538

Status
Completed
 
Locations

Investigative Site

Düsseldorf, Germany, 40225

Status
Completed
 
Locations

Investigative Site

Ulm, Germany, 89081

Status
Completed
 
Locations

Investigative Site

Arnsberg, Germany, 59759

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 10713

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01307

Status
Terminated
 
Locations

Investigative Site

Madrid, Spain, 28006

Status
Completed
 
Locations

Investigative Site

Granada, Spain, 18012

Status
Completed
 
Locations

Investigative Site

Pamplona, Spain, 31008

Status
Completed
 
Locations

Investigative Site

Ciudadela, Argentina, 1702

Status
Completed
 
Locations

Investigative Site

La Plata, Argentina, 1900

Status
Completed
 
Locations

Investigative Site

Buenos Aires, Argentina, 1078

Status
Completed
 
Locations

Investigative Site

Köln, Germany, 50937

Status
Completed
 
Locations

Investigative Site

Magdeburg, Germany, 39120

Status
Completed
 
Locations

Investigative Site

Immenstadt, Germany, 87509

Status
Completed
 
Locations

Investigative Site

Wesel, Germany, 46483

Status
Completed
 
Locations

Investigative Site

LEUVEN, Belgium, 3000

Status
Completed
 
Locations

Investigative Site

BRUXELLES - BRUSSEL, Belgium, 1070

Status
Completed
 
Locations

Investigative Site

Malmö, Sweden, 205 02

Status
Completed
 
Locations

Investigative Site

Växjö, Sweden, 351 85

Status
Completed
 
Locations

Investigative Site

Solna, Sweden, 171 76

Status
Completed
 
Locations

Investigative Site

Wien, Austria, 1160

Status
Completed
 
Locations

Investigative Site

Linz, Austria, 4021

Status
Completed
 
Locations

Investigative Site

Innsbruck, Austria, 6020

Status
Completed
 
Locations

Investigative Site

Feldkirch, Austria, 6807

Status
Completed
 
Locations

Investigative Site

Napoli, Italy, 80131

Status
Completed
 
Locations

Investigative Site

Roma, Italy, 00161

Status
Completed
 
Locations

Investigative Site

Reggio Emilia, Italy, 42100

Status
Completed
 
Locations

Investigative Site

Montreal, Canada, H2W 1T8

Status
Completed
 
Locations

Investigative Site

Montreal, Canada, H1T 2M4

Status
Completed
 
Locations

Investigative Site

Praha 2, Czech Republic, 12808

Status
Completed
 
Locations

Investigative Site

Taipei, Taiwan, China, 10002

Status
Completed
 
Locations

Investigative Site

Kaohsiung, Taiwan, China, 813

Status
Completed
 
Locations

Investigative Site

Bucharest, Romania, 022322

Status
Completed
 
Locations

Investigative Site

Targu Mures, Romania, 540124

Status
Completed
 
Locations

Investigative Site

Pitesti, Romania, 110084

Status
Completed
 
Locations

Investigative Site

Cluj Napoca, Romania, 400001

Status
Completed
 
Locations

Investigative Site

Bucharest, Romania, 011461

Status
Completed
 
Locations

Investigative Site

Bucharest, Romania, 010192

Status
Completed
 
Locations

Investigative Site

Lodz, Poland, 94-048

Status
Completed
 
Locations

Investigative Site

Lublin, Poland, 20-044

Status
Completed
 
Locations

Investigative Site

Poznan, Poland, 61-848

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 02-097

Status
Completed
 
Locations

Investigative Site

UTRECHT, Netherlands, 3584 CX

Status
Completed
 
Locations

Investigative Site

ZWOLLE, Netherlands, 8025 AB

Status
Completed
 
Locations

Investigative Site

ENSCHEDE, Netherlands, 7611 JH

Status
Completed
 
Locations

Investigative Site

EINDHOVEN, Netherlands, 5623 EJ

Status
Completed
 
Locations

Investigative Site

DEN BOSCH, Netherlands, 5223 GZ

Status
Completed
 
Locations

Investigative Site

Prostejov, Czech Republic, 798 11

Status
Completed
 
Locations

Investigative Site

Buenos Aires, Argentina, C1280AEB

Status
Completed
 
Locations

Investigative Site

Bahia Blanca, Argentina, B8001HXM

Status
Completed
 
Locations

Investigative Site

Taipei, Taiwan, China, 11217

Status
Completed
 
Locations

Investigative Site

Porto, Portugal, 4099-001

Status
Completed
 
Locations

Investigative Site

Almada, Portugal, 2805-267

Status
Completed
 
Locations

Investigative Site

Porto, Portugal, 4200-319

Status
Completed
 
Locations

Investigative Site

Lisboa, Portugal, 1169-1024

Status
Completed
 
Locations

Investigative Site

Szekesfehervar, Hungary, 8000

Status
Completed
 
Locations

Investigative Site

Nyiregyhaza, Hungary, 4400

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 03722

Status
Completed
 
Locations

Investigative Site

Seongnam-si, South Korea, 13620

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 152-703

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 137-701

Status
Completed
 
Locations

Investigative Site

Jung-gu Daejeon, South Korea, 35015

Status
Completed
 
Locations

Investigative Site

Goyang-si, South Korea, 10326

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea

Status
Completed
 
Locations

Investigative Site

Kumamoto, Japan, 860-0008

Status
Completed
 
Locations

Investigative Site

Itabashi-ku, Japan, 173-8610

Status
Completed
 
Locations

Investigative Site

Meguro-ku, Japan, 152-8902

Status
Completed
 
Locations

Investigative Site

Beppu, Japan, 874-0011

Status
Completed
 
Locations

Investigative Site

Hamada, Japan, 697-8511

Status
Completed
 
Locations

Investigative Site

Kitakyushu, Japan, 805-0050

Status
Completed
 
Locations

Investigative Site

Fuchu, Japan, 183-0003

Status
Completed
 
Locations

Investigative Site

St. Gallen, Switzerland, 9007

Status
Completed
 
Locations

Investigative Site

Genève, Switzerland, 1205

Status
Completed
 
Locations

Investigative Site

Daegu, South Korea, 42472

Status
Completed
 
Locations

Investigative Site

London, United Kingdom, NW3 2QG

Status
Completed
 
Locations

Investigative Site

Daegu, South Korea, 700-712

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 05368

Status
Completed
 
Locations

Investigative Site

Praha 5, Czech Republic, 150 06

Status
Completed
 
Locations

Investigative Site

Liberec, Czech Republic, 460 63

Status
Completed
 
Locations

Investigative Site

Szeged, Hungary, 6725

Status
Completed
 
Locations

Investigative Site

Gyor, Hungary, 9023

Status
Completed
 
Locations

Investigative Site

Debrecen, Hungary, 4032

Status
Completed
 
Locations

Investigative Site

Bangkok, Thailand, 10700

Status
Completed
 
Locations

Investigative Site

Cheltenham, United Kingdom, GL53 7AN

Status
Completed
 
Locations

Investigative Site

Hull, United Kingdom, HU3 2JZ

Status
Completed
 
Locations

Investigative Site

London, United Kingdom, SW17 0QT

Status
Completed
 
Locations

Investigative Site

Carlisle, United Kingdom, CA2 7HY

Status
Completed
 
Locations

Investigative Site

Worcester, United Kingdom, WR5 1DD

Status
Completed
 
Locations

Investigative Site

Doncaster, United Kingdom, DN2 5LT

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS1 3EX

Status
Completed
 
Locations

Investigative Site

Birmingham, United Kingdom, B9 5SS

Status
Completed
 
Locations

Investigative Site

Newcastle Upon Tyne, United Kingdom, NE7 7DN

Status
Completed
 
Locations

Investigative Site

Kashihara, Japan, 634-8522

Status
Completed
 
Locations

Investigative Site

Rosario, Argentina, S2000PBJ

Status
Completed
 
Locations

Investigative Site

Sofia, Bulgaria, 1407

Status
Completed
 
Locations

Investigative Site

Ruse, Bulgaria, 7002

Status
Completed
 
Locations

Investigative Site

Sofia, Bulgaria, 1606

Status
Completed
 
Locations

Investigative Site

Stara Zagora, Bulgaria, 6000

Status
Completed
 
Locations

Investigative Site

Sofia, Bulgaria, 1431

Status
Completed
 
Locations

Investigative Site

Samokov, Bulgaria, 2000

Status
Completed
 
Locations

Investigative Site

Varna, Bulgaria, 9010

Status
Completed
 
Locations

Investigative Site

Plovdiv, Bulgaria, 4002

Status
Completed
 
Locations

Investigative Site

Linden, United States, 07036

Status
Completed
 
Locations

Investigative Site

BRUXELLES - BRUSSEL, Belgium, 1200

Status
Completed
 
Locations

Investigative Site

BRUXELLES - BRUSSEL, Belgium, 1090

Status
Completed
 
Locations

Investigative Site

Szombathely, Hungary, 9700

Status
Completed
 
Locations

Investigative Site

London, Canada, ON N6A 5W9

Status
Completed
 
Locations

Investigative Site

St. Jerome, Canada, J7Z 5T3

Status
Completed
 
Locations

Investigative Site

Montreal, Canada, H3T 1E2

Status
Completed
 
Locations

Investigative Site

Chicoutimi, Canada, G7H 5H6

Status
Completed
 
Locations

Investigative Site

Montreal, Canada, H1T 1C8

Status
Completed
 
Locations

Investigative Site

Kobe, Japan, 650-0047

Status
Completed
 
Locations

Investigative Site

HEERLEN, Netherlands, 6419 PC

Status
Completed
 
Locations

Investigative Site

Basel, Switzerland, 4031

Status
Completed
 
Locations

Investigative Site

Budapest, Hungary, 1106

Status
Completed
 
Locations

Investigative Site

Oradea, Romania

Status
Completed
 
Locations

Investigative Site

Timisoara, Romania, 300736

Status
Completed
 
Locations

Investigative Site

Ravenna, Italy, 48033

Status
Completed
 
Locations

Investigative Site

Palermo, Italy, 90127

Status
Completed
 
Locations

Investigative Site

POITIERS cedex, France, 86021

Status
Completed
 
Locations

Investigative Site

STRASBOURG, France, 67091

Status
Completed
 
Locations

Investigative Site

TOULOUSE, France, 31300

Status
Completed
 
Locations

Investigative Site

GRENOBLE, France, 38043

Status
Completed
 
Locations

Investigative Site

RENNES CEDEX, France, 35033

Status
Completed
 
Locations

Investigative Site

LIMOGES, France, 87042

Status
Completed
 
Locations

Investigative Site

TOULOUSE, France, 31403

Status
Completed
 
Locations

Investigative Site

NICE, France, 06280

Status
Completed
 
Locations

Investigative Site

MONTPELLIER CEDEX, France, 34295

Status
Completed
 
Locations

Investigative Site

BORDEAUX, France, 33075

Status
Completed
 
Locations

Investigative Site

PARIS, France, 75634

Status
Completed
 
Locations

Investigative Site

PARIS CEDEX 15, France, 75908

Status
Completed
 
Locations

Investigative Site

CASTELNAU LE LEZ, France, 34170

Status
Completed
 
Locations

Investigative Site

CAEN CEDEX, France, 14033

Status
Completed
 
Locations

Investigative Site

Jena, Germany, 07740

Status
Completed
 
Locations

Investigative Site

Lecce, Italy, 73100

Status
Completed
 
Locations

Investigative Site

Cádiz, Spain, 11009

Status
Completed
 
Locations

Investigative Site

Busan, South Korea, 49201

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 06351

Status
Completed
 
Locations

Investigative Site

Daejeon, South Korea, 301-723

Status
Completed
 
Locations

Investigative Site

Amarillo, United States, 79106

Status
Completed
 
Locations

Investigative Site

Fort Payne, United States, 35967

Status
Completed
 
Locations

Investigative Site

Manchester, United Kingdom, M13 9WL

Status
Completed
 
Locations

Investigative Site

Manchester, United Kingdom, M23 9LT

Status
Completed
 
Locations

Investigative Site

Harrow, United Kingdom, HA1 3UJ

Status
Completed
 
Locations

Investigative Site

Sheffield, United Kingdom, S5 7AU

Status
Completed
 
Locations

Investigative Site

Cambridge, United Kingdom, CB3 OLB

Status
Completed
 
Locations

Investigative Site

Krakow, Poland

Status
Completed
 
Locations

Investigative Site

Gatineau, Canada, J8Y 6S8

Status
Completed
 
Locations

Investigative Site

Ottawa, Canada, K1Y 4E9

Status
Completed
 
Locations

Investigative Site

Yambol, Bulgaria, 8600

Status
Completed
 
Locations

Investigative Site

Jacksonville, United States, 32209

Status
Completed
 
Locations

Investigative Site

Tyler, United States, 75701

Status
Completed
 
Locations

Investigative Site

Fort Wayne, United States, 46845

Status
Completed
 
Locations

Investigative Site

Hudson, United States, 34667

Status
Completed
 
Locations

Investigative Site

Shreveport, United States, 71105

Status
Completed
 
Locations

Investigative Site

Dayton, United States, 45414

Status
Completed
 
Locations

Investigative Site

Phoenix, United States, 85006

Status
Completed
 
Locations

Investigative Site

York, United States, 17405

Status
Completed
 
Locations

Investigative Site

Edinburg, United States, 78539

Status
Completed
 
Locations

Investigative Site

Safety Harbor, United States, 34695

Status
Completed
 
Locations

Investigative Site

Lexington, United States, 40536

Status
Completed
 
Locations

Investigative Site

Dallas, United States, 75226

Status
Completed
 
Locations

Investigative Site

New York, United States, 10029

Status
Completed
 
Locations

Investigative Site

Midland, United States, 48670

Status
Completed
 
Locations

Investigative Site

Cincinnati, United States, 45267

Status
Completed
 
Locations

Investigative Site

Charlotte, United States, 28204

Status
Completed
 
Locations

Investigative Site

Wyoming, United States, 49519

Status
Completed
 
Locations

Investigative Site

Lincoln, United States, 68510

Status
Completed
 
Locations

Investigative Site

Freudenstadt, Germany, 72250

Status
Completed
 
Locations

Investigative Site

Ragusa, Italy, 97100

Status
Completed
 
Locations

Investigative Site

Tainan, Taiwan, China, 704

Status
Completed
 
Locations

Investigative Site

Bangkok, Thailand, 10330

Status
Completed
 
Locations

Investigative Site

Khon Kaen, Thailand, 40002

Status
Completed
 
Locations

Investigative Site

Songkla, Thailand, 90110

Status
Completed
 
Locations

Investigative Site

Bangkok, Thailand, 10400

Status
Completed
 
Locations

Investigative Site

Nagakute, Japan, 480-1195

Status
Completed
 
Locations

Investigative Site

Regensburg, Germany, 93053

Status
Completed
 
Locations

Investigative Site

Klagenfurt, Austria, 9020

Status
Completed
 
Locations

Investigative Site

Miyazaki, Japan, 880-2102

Status
Completed
 
Locations

Investigative Site

Bangkok, Thailand

Status
Completed
 
Locations

Investigative Site

LE COUDRAY, France, 28630

Status
Completed
 
Locations

Investigative Site

Avellino, Italy, 83100

Status
Completed
 
Locations

Investigative Site

Milano, Italy, 20132

Status
Completed
 
Locations

Investigative Site

Praha 5, Czech Republic, 15006

Status
Completed
 
Locations

Investigative Site

Kaunas, Lithuania, 45130

Status
Completed
 
Locations

Investigative Site

Panevezys, Lithuania, 35144

Status
Completed
 
Locations

Investigative Site

Kaunas, Lithuania, LT-50009

Status
Completed
 
Locations

Investigative Site

Vilnius, Lithuania, LT-08661

Status
Completed
 
Locations

Investigative Site

Liepaja, Latvia, LV-3414

Status
Completed
 
Locations

Investigative Site

Riga, Latvia, LV-1002

Status
Completed
 
Locations

Investigative Site

Daugavpils, Latvia, LV-5417

Status
Completed
 
Locations

Investigative Site

Riga, Latvia, 1038

Status
Completed
 
Locations

Investigative Site

Bratislava, Slovakia, 851 07

Status
Completed
 
Locations

Investigative Site

Nitra, Slovakia, 949 01

Status
Completed
 
Locations

Investigative Site

Bratislava, Slovakia, 83348

Status
Completed
 
Locations

Investigative Site

Trnava, Slovakia, 91701

Status
Completed
 
Locations

Investigative Site

Dunajska Streda, Slovakia, 92901

Status
Completed
 
Locations

Investigative Site

Zilina, Slovakia, 01001

Status
Completed
 
Locations

Investigative Site

Kosice, Slovakia, 04001

Status
Completed
 
Locations

Investigative Site

La Plata, Argentina, B1900ASM

Status
Completed
 
Locations

Investigative Site

Varese, Italy, 21100

Status
Completed
 
Locations

Investigative Site

Vilnius, Lithuania, LT-10207

Status
Completed
 
Locations

Investigative Site

Bardejov, Slovakia, 085 01

Status
Completed
 
Locations

Investigative Site

Nove Zamky, Slovakia, 940 01

Status
Completed
 
Locations

Investigative Site

Córdoba, Argentina, X5006IKK

Status
Completed
 
Locations

Investigative Site

Corrientes, Argentina, 3400

Status
Completed
 
Locations

Investigative Site

Osaka, Japan, 530-8480

Status
Completed
 
Locations

Investigative Site

Sagamihara, Japan, 252-5188

Status
Completed
 
Locations

Investigative Site

Kagoshima, Japan, 890-8760

Status
Completed
 
Locations

Investigative Site

Osaka, Japan, 530-0012

Status
Completed
 
Locations

Investigative Site

Amagasaki, Japan, 660-8511

Status
Completed
 
Locations

Investigative Site

Takarazuka, Japan, 665-0873

Status
Completed
 
Locations

Investigative Site

Minato, Japan, 108-0073

Status
Completed
 
Locations

Investigative Site

Kawagoe, Japan, 350-8550

Status
Completed
 
Locations

Investigative Site

Covington, United States, 70433

Status
Completed
 
Locations

Investigative Site

Córdoba, Argentina, 5000

Status
Completed
 
Locations

Investigative Site

Belo Horizonte, Brazil, 30140-073

Status
Completed
 
Locations

Investigative Site

Campinas, Brazil, 13060-080

Status
Completed
 
Locations

Investigative Site

Belo Horizonte, Brazil, 30110-090

Status
Completed
 
Locations

Investigative Site

Fortaleza, Brazil, 60430 370

Status
Completed
 
Locations

Investigative Site

Porto Alegre, Brazil, 90619900

Status
Completed
 
Locations

Investigative Site

Belo Horizonte, Brazil, 30140-062

Status
Completed
 
Locations

Investigative Site

Rio de Janeiro, Brazil, 20551-030

Status
Completed
 
Locations

Investigative Site

Belo Horizonte, Brazil, 30130-100

Status
Completed
 
Locations

Investigative Site

Porto Alegre, Brazil

Status
Completed
 
Locations

Investigative Site

Denver, United States, 80220

Status
Completed
 
Locations

Investigative Site

Avondale, United States, 85388

Status
Completed
 
Locations

Investigative Site

VELDHOVEN, Netherlands, 5504 DB

Status
Completed
 
Locations

Investigative Site

London, United Kingdom, W6 8RF

Status
Completed
 
Locations

Investigative Site

Taoyuan, Taiwan, China, 333423

Status
Completed
 
Locations

Investigative Site

Junín, Argentina, B6000BHA

Status
Completed
 
Locations

Investigative Site

Ciudad Auton. de Buenos Aires, Argentina, C1181ACL

Status
Completed
 
Locations

Investigative Site

Clinton, United States, 20735

Status
Completed
 
Locations

Investigative Site

Jackson, United States, 39216

Status
Completed
 
Locations

Investigative Site

New York, United States, 10011

Status
Completed
 
Locations

Investigative Site

Aurora, United States, 80045

Status
Completed
 
Locations

Investigative Site

Omihachiman, Japan, 523-0082

Status
Completed
 
Locations

Investigative Site

Habikino, Japan, 583-0872

Status
Completed
 
Locations

Investigative Site

Philadelphia, United States, 19140

Status
Completed
 
Locations

Investigative Site

São José do Rio Preto, Brazil, 15090

Status
Completed
 
Locations

Investigative Site

Curitiba, Brazil, 80230-130

Status
Completed
 
Locations

Investigative Site

Tatui, Brazil, 18270-170

Status
Completed
 
Locations

Investigative Site

Passo Fundo, Brazil, 99010-080

Status
Completed
 
Locations

Investigative Site

Canoas, Brazil, 92200-000

Status
Completed
 
Locations

Investigative Site

Santo André, Brazil, 09030-010

Status
Completed
 
Locations

Investigative Site

Uberlândia, Brazil, 38411-186

Status
Completed
 
Locations

Investigative Site

São Bernardo do Campo, Brazil, 09715-090

Status
Completed
 
Locations

Investigative Site

Belo Horizonte, Brazil, 30110-130

Status
Completed
 
Locations

Investigative Site

Sofia, Bulgaria, 1309

Status
Completed
 
Locations

Investigative Site

Matsumoto, Japan, 390-8621

Status
Completed
 
Locations

Investigative Site

Matsusaka, Japan, 515-8566

Status
Completed
 
Locations

Investigative Site

Shanghai, China, 200032

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100730

Status
Completed
 
Locations

Investigative Site

Changsha, China, 410011

Status
Completed
 
Locations

Investigative Site

Tianjin, China, 300000

Status
Completed
 
Locations

Investigative Site

Wuhan, China, 430030

Status
Completed
 
Locations

Investigative Site

Haikou, China, 570311

Status
Completed
 
Locations

Investigative Site

Qingdao, China, 266003

Status
Completed
 
Locations

Investigative Site

Wenzhou, China, 325000

Status
Completed
 
Locations

Investigative Site

Wuhan, China, 430014

Status
Completed
 
Locations

Investigative Site

Bratislava 37, Slovakia, 833 48

Status
Completed
 
Locations

Investigative Site

Ivano-Frankivsk, Ukraine, 76014

Status
Completed
 
Locations

Investigative Site

Vinnytsia, Ukraine, 21018

Status
Completed
 
Locations

Investigative Site

Ivano-Frankivsk, Ukraine, 76000

Status
Completed
 
Locations

Investigative Site

Kharkiv, Ukraine, 61018

Status
Completed
 
Locations

Investigative Site

Kyiv, Ukraine, 1601

Status
Completed
 
Locations

Investigative Site

Vancouver, Canada, V5Z 1M9

Status
Completed
 
Locations

Investigative Site

Montreal, Quebec, Canada, H4A 3J1

Status
Completed
 
Locations

Investigative Site

Vila Nova de Gaia, Portugal, 4434-502

Status
Completed
 
Locations

Investigative Site

Ponta Delgada, Portugal, 9500-370

Status
Completed
 
Locations

Investigative Site

Saitama, Japan, 336-8522

Status
Completed
 
Locations

Investigative Site

Tomakomai, Japan, 053-8506

Status
Completed
 
Locations

Investigative Site

Iasi, Romania, 700732

Status
Completed
 
Locations

Investigative Site

Frankfurt, Germany, 60389

Status
Completed
 
Locations

Investigative Site

Fribourg, Switzerland, 1700

Status
Completed
 
Locations

Investigative Site

Baden, Switzerland, 5404

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100083

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100144

Status
Active, not recruiting
 
Locations

Investigative Site

Taiyuan, China, 030001

Status
Completed
 
Locations

Investigative Site

Guangzhou, China, 510080

Status
Completed
 
Locations

Investigative Site

Kyoto, Japan, 615-8256

Status
Completed
 
Locations

Investigative Site

Wien, Austria, 1090

Status
Completed
 
Locations

Investigative Site

Elk Grove Village, United States, 60007

Status
Completed
 
Locations

Investigative Site

Zaporizhzhya, Ukraine, 69600

Status
Completed
 
Locations

Investigative Site

Lviv, Ukraine, 79010

Status
Completed
 
Locations

Investigative Site

Changchun, China, 130021

Status
Completed
 
Locations

Investigative Site

Guangzhou, China, 510630

Status
Completed
 
Locations

Investigative Site

Zhangzhou, China, 363000

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100053

Status
Completed
 
Locations

Investigative Site

Nanjing, China, 210006

Status
Completed
 
Locations

Investigative Site

Taizhou, China, 317000

Status
Completed
 
Locations

Investigative Site

Guangzhou, China

Status
Completed
 
Locations

Investigative Site

Zhongshan, China, 528403

Status
Completed
 
Locations

Investigative Site

Changzhou, China, 213003

Status
Completed
 
Locations

Investigative Site

Zhanjiang, China, 524001

Status
Completed
 
Locations

Investigative Site

Xi'an, China, 710038

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100853

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100029

Status
Completed
 
Locations

Investigative Site

Bielefeld, Germany, 33604

Status
Completed
 
Locations

Investigative Site

Kiev, Ukraine, 3680

Status
Completed
 
Locations

Investigative Site

Osaka, Japan, 558-8558

Status
Completed
 
Locations

Investigative Site

KORTRIJK, Belgium, 8500

Status
Completed
 
Locations

Investigative Site

Morioka, Japan, 020-0066

Status
Completed
 
Locations

Investigative Site

Shanghai, China, 200040

Status
Completed
 
Locations

Investigative Site

Suginami-ku, Japan, 166-0001

Status
Completed
 
Locations

Investigative Site

Kyoto, Japan, 604-8401

Status
Completed
 
Locations

Investigative Site

Tver, Russia, 170036

Status
Completed
 
Locations

Investigative Site

Tallinn, Estonia, 11312

Status
Completed
 
Locations

Investigative Site

Incheon, South Korea, 21565

Status
Completed
 
Locations

Investigative Site

Burgas, Bulgaria, 8000

Status
Completed
 
Locations

Investigative Site

Panagyurishte, Bulgaria, 4500

Status
Completed
 
Locations

Investigative Site

Takamatsu, Japan, 760-8557

Status
Completed
 
Locations

Investigative Site

Sapporo, Japan, 064-8622

Status
Completed
 
Locations

Investigative Site

Katowice, Poland, 40-040

Status
Completed
 
Locations

Investigative Site

Tartu, Estonia, 50406

Status
Completed
 
Locations

Investigative Site

BORDEAUX, France, 33000

Status
Completed
 
Locations

Investigative Site

Hsinchu City, Taiwan, China, 300

Status
Completed
 
Locations

Investigative Site

Santa Fe, Argentina, S3000FWO

Status
Completed
 
Locations

Investigative Site

Ruse, Bulgaria, 7013

Status
Completed
 
Locations

Investigative Site

São Paulo, Brazil, 01323-903

Status
Completed
 
Locations

Investigative Site

Göteborg, Sweden, 413 46

Status
Completed
 
Locations

Investigative Site

Linköping, Sweden, 582 85

Status
Completed
 
Locations

Investigative Site

Rosario, Argentina, 2000

Status
Completed
 
Locations

Investigative Site

Barcelona, Spain, 08035

Status
Completed
 
Locations

Investigative Site

Córdoba, Argentina, X5000AAX

Status
Completed
 
Locations

Investigative Site

Tampere, Finland, 33521

Status
Completed
 
Locations

Investigative Site

Hefei, China, 230001

Status
Completed
 
Locations

Investigative Site

Wien, Austria, 1170

Status
Completed
 
Locations

Investigative Site

Changsha, China, 410008

Status
Completed
 
Locations

Investigative Site

Helsinki, Finland, 00290

Status
Completed
 
Locations

Investigative Site

Fuzhou, China, 350025

Status
Completed
 
Locations

Investigative Site

Lublin, Poland, 20-718

Status
Completed
 
Locations

Investigative Site

Wroclaw, Poland, 50-981

Status
Completed
 
Locations

Investigative Site

Dnipro, Ukraine, 49000

Status
Completed
 
Locations

Investigative Site

Kawasaki, Japan, 215-0026

Status
Completed
 
Locations

Investigative Site

Santa Rosa, Argentina, 6300

Status
Completed
 
Locations

Investigative Site

Gdynia, Poland, 81-338

Status
Completed
 
Locations

Investigative Site

Chongqing, China

Status
Active, not recruiting
 
Locations

Investigative Site

Oulu, Finland, 90220

Status
Completed
 
Locations

Investigative Site

San Isidro, Argentina, B1642DCD

Status
Completed
 
Locations

Investigative Site

Tallinn, Estonia, 13419

Status
Completed
 
Locations

Investigative Site

Novosibirsk, Russia, 630055

Status
Completed
 
Locations

Investigative Site

Novosibirsk, Russia, 630087

Status
Completed
 
Locations

Investigative Site

Voronezh, Russia, 394066

Status
Completed
 
Locations

Investigative Site

Kaohsiung, Taiwan, China, 82445

Status
Active, not recruiting
 
Locations

Investigative Site

St. Petersburg, Russia, 195271

Status
Completed
 
Locations

Investigative Site

Tomsk, Russia, 634012

Status
Completed
 
Locations

Investigative Site

St. Petersburg, Russia, 194354

Status
Completed
 
Locations

Investigative Site

Nizhny Novgorod, Russia, 603155

Status
Completed
 
Locations

Investigative Site

Moscow, Russia, 105077

Status
Completed
 
Locations

Investigative Site

Ryazan, Russia, 390026

Status
Completed
 
Locations

Investigative Site

Belgrade, Serbia, 11000

Status
Completed
 
Locations

Investigative Site

Rostov-on-Don, Russia, 344022

Status
Completed
 
Locations

Investigative Site

Kemerovo, Russia, 650002

Status
Completed
 
Locations

Investigative Site

Belgrade, Serbia, 11080

Status
Completed
 
Locations

Investigative Site

Belgrade, Serbia, 11040

Status
Completed
 
Locations

Investigative Site

Nis, Serbia, 18000

Status
Completed
 
Locations

Investigative Site

Moscow, Russia, 117997

Status
Completed
 
Locations

Investigative Site

Beograd, Serbia, 11000

Status
Completed
 
Locations

Investigative Site

Chur, Switzerland, 7000

Status
Completed
 
Locations

Investigative Site

St. Petersburg, Russia, 191015

Status
Completed
 
Locations

Investigative Site

St. Petersburg, Russia, 194291

Status
Completed
 
Locations

Investigative Site

Moscow, Russia, 129327

Status
Completed
 
Locations

Investigative Site

Moscow, Russia, 115682

Status
Completed
 
Locations

Investigative Site

San Martín, Argentina, 1650

Status
Completed
 
Locations

Investigative Site

Saint-Petersburg, Russia, 197374

Status
Completed
 

Trial Design