check_circleStudy Completed
Peripheral Artery Disease
Bayer Identifier:
17454
ClinicalTrials.gov Identifier:
EudraCT Number:
EU CT Number:
Not Available
Efficacy and safety of rivaroxaban in reducing the risk of major thrombotic vascular events in subjects with symptomatic peripheral artery disease undergoing peripheral revascularization procedures of the lower extremities
Trial purpose
The purpose of study was to test whether rivaroxaban added to standard of care treatment, when compared to placebo, had the potential to reduce the incidence of the clinical events related to the clots and complications of the heart and brain (CV death, MI, or stroke) or the legs (acute limb ischemia or major amputation) in patients who had undergone recent procedure(s) to improve the blood flow of their legs.
Key Participants Requirements
Sex
BothAge
50 - N/ATrial summary
Enrollment Goal
6564Trial Dates
August 2015 - January 2020Phase
Phase 3Could I Receive a placebo
YesProducts
Xarelto (Rivaroxaban, BAY59-7939)Accepts Healthy Volunteer
NoWhere to participate
Status | Institution | Location |
---|---|---|
Completed | Shreveport, 71103, United States | |
Completed | Wellington, 33449, United States | |
Completed | Winston-Salem, 27103, United States | |
Withdrawn | Toledo, 43606, United States | |
Withdrawn | El Cajon, 92020, United States | |
Withdrawn | Cottonwood, 86326, United States | |
Completed | Muskegon, 49444, United States | |
Completed | Lansing, 48912, United States | |
Completed | Saint Louis, 63128, United States | |
Completed | Northridge, 91325, United States | |
Completed | Roseville, 95661, United States | |
Withdrawn | New Braunfels, 78130, United States | |
Completed | Camp Hill, 17011, United States | |
Completed | San Antonio, 78258, United States | |
Withdrawn | Moreno Valley, 92553, United States | |
Completed | Tupelo, 38801, United States | |
Completed | Kingwood, 77339, United States | |
Completed | Birmingham, 35294-0012, United States | |
Completed | Fort Wayne, 46804, United States | |
Completed | Glendale, 85340, United States | |
Withdrawn | Valparaiso, 46383, United States | |
Completed | Alexandria, 71301, United States | |
Completed | Arlington Heights, 60005, United States | |
Withdrawn | Corpus Christi, 78404, United States | |
Withdrawn | Windsor Heights, 50324, United States | |
Completed | Pensacola, 32501, United States | |
Completed | Clearwater, 33756, United States | |
Withdrawn | New Port Richey, 34653, United States | |
Completed | Teaneck, 07666, United States | |
Completed | Madison, 53713, United States | |
Completed | Saratoga Springs, 12866, United States | |
Withdrawn | Clearwater, 33756, United States | |
Withdrawn | Jackson, 38305, United States | |
Completed | Atlantis, 33462, United States | |
Completed | Hillsboro, 97123, United States | |
Completed | Tallahassee, 32308, United States | |
Withdrawn | Covington, 70433, United States | |
Completed | Huntsville, 77340, United States | |
Withdrawn | Voorhees, 08043, United States | |
Completed | Torrance, 90502, United States | |
Completed | Springfield, 62701, United States | |
Withdrawn | Rock Island, 61201-5351, United States | |
Withdrawn | Layton, 84041, United States | |
Completed | Wausau, 54401, United States | |
Withdrawn | Raleigh, 27610, United States | |
Completed | Lincoln, 68506, United States | |
Withdrawn | Salt Lake City, 84132, United States | |
Withdrawn | Fort Smith, 72901, United States | |
Withdrawn | Newark, 19713, United States | |
Completed | Mission Viejo, 92691, United States | |
Completed | Manitowoc, 54220, United States | |
Withdrawn | Bridgeport, 06610, United States | |
Completed | Gainesville, 32605, United States | |
Withdrawn | Owensboro, 42303, United States | |
Withdrawn | Worcester, 01655, United States | |
Completed | Lewiston, 04240, United States | |
Completed | Durham, 27710, United States | |
Withdrawn | Indianapolis, 46237, United States | |
Completed | Jacksonville, 32216, United States | |
Completed | Knoxville, 37934, United States | |
Completed | Bay City, 48708, United States | |
Completed | Ocala, 34474, United States | |
Withdrawn | Asheville, 28801, United States | |
Withdrawn | Providence, 02906, United States | |
Withdrawn | Bay City, 48708, United States | |
Withdrawn | Falls Church, 22042, United States | |
Completed | Greenville, 29657, United States | |
Withdrawn | Pittsburgh, 15240, United States | |
Withdrawn | Erie, 16502, United States | |
Withdrawn | Wormleysburg, 17043, United States | |
Completed | Philadelphia, 19104, United States | |
Completed | Erie, 16507, United States | |
Completed | Toledo, 43614, United States | |
Completed | Cincinnati, 45219, United States | |
Withdrawn | Columbus, 43215, United States | |
Completed | Springfield, 45505, United States | |
Withdrawn | Bronx, 10469, United States | |
Withdrawn | East Orange, 07918, United States | |
Withdrawn | Summit, 07901, United States | |
Completed | Flemington, 08822, United States | |
Completed | Lebanon, 03756-1000, United States | |
Completed | Chapel Hill, 27517, United States | |
Withdrawn | Raleigh, 27607, United States | |
Withdrawn | Marquette, 49855, United States | |
Withdrawn | Detroit, 48236, United States | |
Completed | Dearborn, 48126, United States | |
Withdrawn | Mount Clemens, 48043, United States | |
Withdrawn | Flint, 48503, United States | |
Completed | Detroit, 48201, United States | |
Withdrawn | Kalamazoo, 49048, United States | |
Withdrawn | Beltsville, 20705, United States | |
Completed | Dallas, 75216-7167, United States | |
Withdrawn | New Brunswick, 08901, United States | |
Completed | Barcelona, 08036, Spain | |
Completed | L'Hospitalet de Llobregat, 08907, Spain | |
Completed | Tarragona, 43005, Spain | |
Completed | Ciudad Real, 13005, Spain | |
Completed | Graz, 8036, Austria | |
Completed | Wien, 1140, Austria | |
Withdrawn | Baltimore, United States | |
Completed | Baltimore, 21201-1595, United States | |
Completed | Baltimore, 21218, United States | |
Withdrawn | Boston, 02118, United States | |
Withdrawn | Crestview Hills, 41017-5460, United States | |
Withdrawn | Indianapolis, 46290, United States | |
Completed | Merrillville, 46410, United States | |
Withdrawn | Tucker, 30084, United States | |
Withdrawn | Jacksonville, 32204, United States | |
Withdrawn | Tampa, 33613, United States | |
Withdrawn | Miami Beach, 33140, United States | |
Withdrawn | Jacksonville, 32216, United States | |
Completed | Miami, 33173, United States | |
Completed | Daytona Beach, 32117, United States | |
Completed | Washington, 20422, United States | |
Completed | Washington, 20007, United States | |
Completed | Kingwood, 77339, United States | |
Completed | Iowa City, 52242, United States | |
Completed | Urbana, 61801, United States | |
Completed | Springfield, 65807, United States | |
Withdrawn | Milwaukee, 53215, United States | |
Completed | Victoria, 77901, United States | |
Withdrawn | McAllen, 78503, United States | |
Withdrawn | Galveston, 77555-0587, United States | |
Withdrawn | Houston, 77030, United States | |
Completed | Austin, 78705, United States | |
Withdrawn | Waco, 76712, United States | |
Withdrawn | Houston, 77024, United States | |
Completed | Humble, 77338, United States | |
Withdrawn | San Antonio, 78217, United States | |
Completed | Rapid City, 57702, United States | |
Completed | Torino, 10126, Italy | |
Completed | Macerata, 62100, Italy | |
Completed | Perugia, 06132, Italy | |
Withdrawn | Tulsa, 74104, United States | |
Completed | Oklahoma City, 73135, United States | |
Withdrawn | Oklahoma City, 73104, United States | |
Completed | Minot, 58701, United States | |
Withdrawn | Kansas City, 64111, United States | |
Withdrawn | St. Louis, 63110, United States | |
Withdrawn | Columbia, 65201, United States | |
Completed | St. Louis, 63128, United States | |
Completed | Coon Rapids, 55433, United States | |
Completed | St. Cloud, 56303, United States | |
Withdrawn | New Orleans, 70121, United States | |
Withdrawn | Shreveport, 71111, United States | |
Withdrawn | Waterloo, 50702, United States | |
Withdrawn | Little Rock, 72211, United States | |
Completed | Alexander City, 35010, United States | |
Completed | Huntsville, 35801-4317, United States | |
Withdrawn | Birmingham, 35235, United States | |
Completed | Houston, 77030, United States | |
Withdrawn | La Jolla, 92037, United States | |
Withdrawn | Seattle, 98122, United States | |
Completed | Palo Alto, 94304, United States | |
Withdrawn | La Jolla, 92037, United States | |
Completed | Stanford, 94305, United States | |
Completed | Hamilton, L8L 2X2, Canada | |
Completed | Winnipeg, R2H 2A6, Canada | |
Completed | Leipzig, 04103, Germany | |
Completed | Kaiserslautern, 67657, Germany | |
Completed | Münster, 48149, Germany | |
Completed | Berlin, 10787, Germany | |
Completed | Bad Krozingen, 79189, Germany | |
Completed | Dresden, 01099, Germany | |
Completed | Frankfurt, 65929, Germany | |
Withdrawn | Riesa, 01589, Germany | |
Completed | GENT, 9000, Belgium | |
Completed | GENK, 3600, Belgium | |
Completed | Springfield, 62702, United States | |
Withdrawn | Brampton, L6Z 4N5, Canada | |
Completed | Minato-ku, 108-8329, Japan | |
Completed | Kitakyushu, 802-8555, Japan | |
Completed | Shibukawa, 377-0061, Japan | |
Completed | Kurume, 830-8577, Japan | |
Completed | Himeji, 671-1227, Japan | |
Completed | Matsuyama, 790-8524, Japan | |
Completed | Asahikwa, 078-8510, Japan | |
Completed | Hatsukaichi, 738-8503, Japan | |
Withdrawn | Fukuoka, 810-8563, Japan | |
Completed | Bydgoszcz, 85-094, Poland | |
Completed | Bunkyo-ku, 113-8519, Japan | |
Completed | Bologna, 40138, Italy | |
Completed | Firenze, 50134, Italy | |
Completed | Potenza, 85100, Italy | |
Completed | Coronel Suarez, B7540GHD, Argentina | |
Completed | Mar del Plata, 7600, Argentina | |
Completed | Rosario, S2000QID, Argentina | |
Completed | Buenos Aires, C1428ART, Argentina | |
Completed | Buenos Aires, C1119ACN, Argentina | |
Withdrawn | Hamburg, 20099, Germany | |
Completed | München, 80331, Germany | |
Completed | Darmstadt, 64276, Germany | |
Completed | Karlsbad, 76307, Germany | |
Completed | Mainz, 55131, Germany | |
Completed | Heidelberg, 69129, Germany | |
Completed | Dresden, 01067, Germany | |
Completed | Hamburg, 20246, Germany | |
Completed | München, 81675, Germany | |
Completed | München, 80336, Germany | |
Withdrawn | Leipzig, 04289, Germany | |
Completed | Krefeld, 47805, Germany | |
Completed | Karlsruhe, 76133, Germany | |
Completed | Rosenheim, 83022, Germany | |
Completed | Sonneberg, 96515, Germany | |
Completed | Bern, 3010, Switzerland | |
Completed | Luzern, 6000, Switzerland | |
Withdrawn | Zürich, 8091, Switzerland | |
Completed | St. John's, A1C 2H6, Canada | |
Completed | Quebec, G1L 3L5, Canada | |
Completed | Warszawa, 01-211, Poland | |
Completed | Szczecin, 70-111, Poland | |
Completed | Bialystok, 15_111, Poland | |
Withdrawn | Prague, 14021, Czechia | |
Completed | Hodonin, 69501, Czechia | |
Completed | Hradec kralove, 500 05, Czechia | |
Completed | Vratimov, 73932, Czechia | |
Completed | Olomouc, 775 20, Czechia | |
Withdrawn | Pardubice, 53002, Czechia | |
Completed | Warszawa, 01-868, Poland | |
Completed | Sapporo, 060-0031, Japan | |
Withdrawn | Sapporo, 060-0031, Japan | |
Completed | Gifu, 500-8717, Japan | |
Completed | Kladno, 27259, Czechia | |
Completed | Plzen, 30599, Czechia | |
Completed | København Ø, 2100, Denmark | |
Completed | Aarhus N, 8200, Denmark | |
Completed | Viborg, 8800, Denmark | |
Completed | Kolding, 6000, Denmark | |
Completed | Odense C, 5000, Denmark | |
Completed | Miskolc, 3526, Hungary | |
Completed | Budapest, 1115, Hungary | |
Completed | Kistarcsa, 2143, Hungary | |
Completed | Kaposvar, 7400, Hungary | |
Completed | Shizuoka, 420-8630, Japan | |
Completed | Pecs, 7624, Hungary | |
Completed | Budapest, 1085, Hungary | |
Completed | Sabadell, 08208, Spain | |
Completed | Brno, 656 91, Czechia | |
Completed | Praha 10, 10100, Czechia | |
Completed | A Coruña, 15006, Spain | |
Completed | Kobe, 651-0053, Japan | |
Completed | Itabashi-ku, 173-0015, Japan | |
Completed | Himeji, 670-0981, Japan | |
Completed | Bad Friedrichshall, 74177, Germany | |
Completed | Bremen, 28277, Germany | |
Withdrawn | Marburg, 35043, Germany | |
Withdrawn | Bad Bevensen, 29549, Germany | |
Completed | Erlangen, 91054, Germany | |
Withdrawn | Flensburg, 24939, Germany | |
Completed | Frankfurt, 60596, Germany | |
Withdrawn | Darmstadt, 64276, Germany | |
Withdrawn | Altenburg, 04600, Germany | |
Withdrawn | Berlin, 10787, Germany | |
Completed | Bad Nauheim, 61231, Germany | |
Completed | Lübeck, 23538, Germany | |
Completed | Düsseldorf, 40225, Germany | |
Completed | Ulm, 89081, Germany | |
Completed | Arnsberg, 59759, Germany | |
Completed | Berlin, 10713, Germany | |
Withdrawn | Jena, 07740, Germany | |
Withdrawn | Altenburg, 04600, Germany | |
Terminated | Dresden, 01307, Germany | |
Withdrawn | Barcelona, 08041, Spain | |
Withdrawn | Badalona, 08916, Spain | |
Withdrawn | Palma de Mallorca, 07120, Spain | |
Completed | Madrid, 28006, Spain | |
Completed | Granada, 18012, Spain | |
Completed | Pamplona, 31008, Spain | |
Completed | Ciudadela, 1702, Argentina | |
Completed | La Plata, 1900, Argentina | |
Completed | Buenos Aires, 1078, Argentina | |
Completed | Köln, 50937, Germany | |
Completed | Magdeburg, 39120, Germany | |
Completed | Immenstadt, 87509, Germany | |
Withdrawn | Heidelberg, 69120, Germany | |
Withdrawn | Merseburg, 06217, Germany | |
Withdrawn | Mainz, 55131, Germany | |
Completed | Wesel, 46483, Germany | |
Withdrawn | Münster, 48145, Germany | |
Withdrawn | Heide, 25746, Germany | |
Completed | LEUVEN, 3000, Belgium | |
Withdrawn | NAMUR, 5000, Belgium | |
Completed | BRUXELLES - BRUSSEL, 1070, Belgium | |
Completed | Malmö, 205 02, Sweden | |
Withdrawn | Västerås, 721 89, Sweden | |
Completed | Växjö, 351 85, Sweden | |
Completed | Solna, 171 76, Sweden | |
Completed | Wien, 1160, Austria | |
Completed | Linz, 4021, Austria | |
Completed | Innsbruck, 6020, Austria | |
Completed | Feldkirch, 6807, Austria | |
Withdrawn | Graz, 8036, Austria | |
Completed | Napoli, 80131, Italy | |
Completed | Roma, 00161, Italy | |
Completed | Reggio Emilia, 42100, Italy | |
Withdrawn | Piacenza, 29121, Italy | |
Withdrawn | Roma, 00135, Italy | |
Completed | Montreal, H2W 1T8, Canada | |
Completed | Montreal, H1T 2M4, Canada | |
Withdrawn | Barrie, L4M 5K3, Canada | |
Completed | Praha 2, 12808, Czechia | |
Completed | Taipei, 10002, Taiwan | |
Completed | Kaohsiung, 813, Taiwan | |
Completed | Bucharest, 022322, Romania | |
Completed | Targu Mures, 540124, Romania | |
Completed | Pitesti, 110084, Romania | |
Completed | Bucharest, 022322, Romania | |
Completed | Cluj Napoca, 400001, Romania | |
Completed | Bucharest, 011461, Romania | |
Completed | Bucharest, 010192, Romania | |
Completed | Lodz, 94-048, Poland | |
Completed | Lublin, 20-044, Poland | |
Completed | Poznan, 61-848, Poland | |
Completed | Warszawa, 02-097, Poland | |
Withdrawn | Orense, 32005, Spain | |
Withdrawn | ROTTERDAM, 3079 DZ, Netherlands | |
Completed | UTRECHT, 3584 CX, Netherlands | |
Completed | ZWOLLE, 8025 AB, Netherlands | |
Completed | ENSCHEDE, 7611 JH, Netherlands | |
Completed | EINDHOVEN, 5623 EJ, Netherlands | |
Withdrawn | NIEUWEGEIN, 3435 CM, Netherlands | |
Withdrawn | BREDA, 4818 CK, Netherlands | |
Completed | DEN BOSCH, 5223 GZ, Netherlands | |
Completed | Prostejov, 798 11, Czechia | |
Completed | Buenos Aires, C1280AEB, Argentina | |
Completed | Bahia Blanca, B8001HXM, Argentina | |
Completed | Taipei, 11217, Taiwan | |
Withdrawn | Porto, 4100-180, Portugal | |
Withdrawn | Lisboa, 1649-035, Portugal | |
Completed | Porto, 4099-001, Portugal | |
Completed | Almada, 2805-267, Portugal | |
Completed | Porto, 4200-319, Portugal | |
Completed | Lisboa, 1169-1024, Portugal | |
Completed | Szekesfehervar, 8000, Hungary | |
Completed | Nyiregyhaza, 4400, Hungary | |
Completed | Seoul, 03722, Korea, Republic Of | |
Completed | Seongnam-si, 13620, Korea, Republic Of | |
Completed | Seoul, 152-703, Korea, Republic Of | |
Completed | Seoul, 137-701, Korea, Republic Of | |
Completed | Jung-gu Daejeon, 35015, Korea, Republic Of | |
Completed | Goyang-si, 10326, Korea, Republic Of | |
Completed | Seoul, Korea, Republic Of | |
Withdrawn | Yatsushiro, 866-8533, Japan | |
Completed | Kumamoto, 860-0008, Japan | |
Withdrawn | Fukui, 918-8503, Japan | |
Completed | Itabashi-ku, 173-8610, Japan | |
Withdrawn | Matsumoto, 390-8621, Japan | |
Completed | Meguro-ku, 152-8902, Japan | |
Completed | Beppu, 874-0011, Japan | |
Completed | Hamada, 697-8511, Japan | |
Completed | Kitakyushu, 805-0050, Japan | |
Completed | Fuchu, 183-0003, Japan | |
Completed | St. Gallen, 9007, Switzerland | |
Completed | Genève, 1205, Switzerland | |
Completed | Daegu, 42472, Korea, Republic Of | |
Completed | London, NW3 2QG, United Kingdom | |
Withdrawn | Dundee, DD1 9SY, United Kingdom | |
Completed | Daegu, 700-712, Korea, Republic Of | |
Completed | Seoul, 05368, Korea, Republic Of | |
Completed | Praha 5, 150 06, Czechia | |
Completed | Liberec, 460 63, Czechia | |
Completed | Szeged, 6725, Hungary | |
Completed | Gyor, 9023, Hungary | |
Completed | Debrecen, 4032, Hungary | |
Completed | Bangkok, 10700, Thailand | |
Completed | Cheltenham, GL53 7AN, United Kingdom | |
Completed | Hull, HU3 2JZ, United Kingdom | |
Withdrawn | Leicester, LE1 5WW, United Kingdom | |
Completed | London, SW17 0QT, United Kingdom | |
Completed | Carlisle, CA2 7HY, United Kingdom | |
Completed | Worcester, WR5 1DD, United Kingdom | |
Completed | Doncaster, DN2 5LT, United Kingdom | |
Completed | Leeds, LS1 3EX, United Kingdom | |
Completed | Birmingham, B9 5SS, United Kingdom | |
Completed | Newcastle Upon Tyne, NE7 7DN, United Kingdom | |
Completed | Kashihara, 634-8522, Japan | |
Withdrawn | Sapporo, 065-0027, Japan | |
Completed | Rosario, S2000PBJ, Argentina | |
Completed | Sofia, 1407, Bulgaria | |
Completed | Ruse, 7002, Bulgaria | |
Completed | Sofia, 1407, Bulgaria | |
Completed | Sofia, 1606, Bulgaria | |
Completed | Sofia, 1606, Bulgaria | |
Completed | Stara Zagora, 6000, Bulgaria | |
Completed | Sofia, 1407, Bulgaria | |
Completed | Sofia, 1606, Bulgaria | |
Completed | Sofia, 1431, Bulgaria | |
Completed | Samokov, 2000, Bulgaria | |
Completed | Sofia, 1606, Bulgaria | |
Completed | Varna, 9010, Bulgaria | |
Completed | Plovdiv, 4002, Bulgaria | |
Withdrawn | Sofia, 1000, Bulgaria | |
Completed | Linden, 07036, United States | |
Withdrawn | OVERPELT, 3900, Belgium | |
Completed | BRUXELLES - BRUSSEL, 1200, Belgium | |
Completed | BRUXELLES - BRUSSEL, 1090, Belgium | |
Completed | Szombathely, 9700, Hungary | |
Withdrawn | Jicin, 506 01, Czechia | |
Completed | London, ON N6A 5W9, Canada | |
Completed | St. Jerome, J7Z 5T3, Canada | |
Completed | Montreal, H3T 1E2, Canada | |
Completed | Chicoutimi, G7H 5H6, Canada | |
Completed | Montreal, H1T 1C8, Canada | |
Completed | Kobe, 650-0047, Japan | |
Withdrawn | GRONINGEN, 9700 RB, Netherlands | |
Completed | HEERLEN, 6419 PC, Netherlands | |
Completed | Basel, 4031, Switzerland | |
Withdrawn | Frauenfeld, 8501, Switzerland | |
Completed | Budapest, 1106, Hungary | |
Completed | Oradea, Romania | |
Completed | Timisoara, 300736, Romania | |
Withdrawn | Cluj-Napoca, 400006, Romania | |
Completed | Ravenna, 48033, Italy | |
Completed | Palermo, 90127, Italy | |
Completed | POITIERS cedex, 86021, France | |
Completed | STRASBOURG, 67091, France | |
Completed | TOULOUSE, 31300, France | |
Completed | GRENOBLE, 38043, France | |
Completed | RENNES CEDEX, 35033, France | |
Withdrawn | AMIENS, 80000, France | |
Completed | LIMOGES, 87042, France | |
Completed | TOULOUSE, 31403, France | |
Completed | NICE, 06280, France | |
Completed | MONTPELLIER CEDEX, 34295, France | |
Completed | BORDEAUX, 33075, France | |
Completed | PARIS, 75634, France | |
Completed | PARIS CEDEX 15, 75908, France | |
Completed | CASTELNAU LE LEZ, 34170, France | |
Completed | CAEN CEDEX, 14033, France | |
Withdrawn | Lisboa, 1500-458, Portugal | |
Completed | Jena, 07740, Germany | |
Completed | Lecce, 73100, Italy | |
Completed | Cádiz, 11009, Spain | |
Completed | Busan, 49201, Korea, Republic Of | |
Completed | Seoul, 06351, Korea, Republic Of | |
Completed | Daejeon, 301-723, Korea, Republic Of | |
Completed | Amarillo, 79106, United States | |
Completed | Fort Payne, 35967, United States | |
Completed | Manchester, M13 9WL, United Kingdom | |
Completed | Manchester, M23 9LT, United Kingdom | |
Completed | Harrow, HA1 3UJ, United Kingdom | |
Completed | Sheffield, S5 7AU, United Kingdom | |
Completed | Cambridge, CB3 OLB, United Kingdom | |
Completed | Krakow, Poland | |
Completed | Gatineau, J8Y 6S8, Canada | |
Completed | Ottawa, K1Y 4E9, Canada | |
Completed | Yambol, 8600, Bulgaria | |
Completed | Jacksonville, 32209, United States | |
Withdrawn | Mobile, 36617, United States | |
Completed | Tyler, 75701, United States | |
Completed | Fort Wayne, 46845, United States | |
Completed | Hudson, 34667, United States | |
Completed | Shreveport, 71105, United States | |
Withdrawn | Philadelphia, 19106, United States | |
Withdrawn | Chicago, 60611, United States | |
Withdrawn | South Charleston, 25309, United States | |
Withdrawn | Tucson, 85724, United States | |
Completed | Dayton, 45414, United States | |
Withdrawn | Tullahoma, 37388, United States | |
Withdrawn | San Diego, 92120, United States | |
Withdrawn | Newark, 19713, United States | |
Withdrawn | Skokie, 60076, United States | |
Withdrawn | Largo, 33777, United States | |
Withdrawn | Tacoma, 98405-2433, United States | |
Withdrawn | Torrance, 90505, United States | |
Withdrawn | Tomball, 77375, United States | |
Withdrawn | Fort Wayne, 46804, United States | |
Withdrawn | Boston, 02115-6195, United States | |
Completed | Phoenix, 85006, United States | |
Completed | York, 17405, United States | |
Completed | Edinburg, 78539, United States | |
Completed | Safety Harbor, 34695, United States | |
Withdrawn | Hartford, 06102-5037, United States | |
Completed | Lexington, 40536, United States | |
Completed | Dallas, 75226, United States | |
Withdrawn | Stony Brook, 11794, United States | |
Completed | New York, 10029, United States | |
Withdrawn | Lexington, 40536, United States | |
Withdrawn | Minneapolis, 55455, United States | |
Completed | Midland, 48670, United States | |
Withdrawn | Oakbrook Terrace, 60181, United States | |
Completed | Cincinnati, 45267, United States | |
Completed | Charlotte, 28204, United States | |
Completed | Wyoming, 49519, United States | |
Withdrawn | Atlanta, 30308, United States | |
Completed | Lincoln, 68510, United States | |
Withdrawn | Clearwater, 33756, United States | |
Completed | Freudenstadt, 72250, Germany | |
Withdrawn | Napoli, 80131, Italy | |
Completed | Ragusa, 97100, Italy | |
Completed | Tainan, 704, Taiwan | |
Completed | Bangkok, 10330, Thailand | |
Completed | Khon Kaen, 40002, Thailand | |
Completed | Songkla, 90110, Thailand | |
Completed | Bangkok, 10400, Thailand | |
Completed | Nagakute, 480-1195, Japan | |
Withdrawn | Nagoya, 466-8560, Japan | |
Withdrawn | Bonn, 53105, Germany | |
Completed | Regensburg, 93053, Germany | |
Completed | Klagenfurt, 9020, Austria | |
Completed | Miyazaki, 880-2102, Japan | |
Completed | Bangkok, Thailand | |
Completed | LE COUDRAY, 28630, France | |
Completed | Avellino, 83100, Italy | |
Completed | Napoli, 80131, Italy | |
Completed | Milano, 20132, Italy | |
Withdrawn | Chieti, 66013, Italy | |
Withdrawn | Padova, 35128, Italy | |
Completed | Praha 5, 15006, Czechia | |
Completed | Kaunas, 45130, Lithuania | |
Completed | Panevezys, 35144, Lithuania | |
Completed | Kaunas, LT-50009, Lithuania | |
Completed | Vilnius, LT-08661, Lithuania | |
Completed | Liepaja, LV-3414, Latvia | |
Completed | Riga, LV-1002, Latvia | |
Completed | Daugavpils, LV-5417, Latvia | |
Completed | Riga, 1038, Latvia | |
Withdrawn | Bratislava, 813 69, Slovakia | |
Completed | Bratislava, 851 07, Slovakia | |
Completed | Nitra, 949 01, Slovakia | |
Completed | Bratislava, 83348, Slovakia | |
Completed | Trnava, 91701, Slovakia | |
Completed | Dunajska Streda, 92901, Slovakia | |
Completed | Trnava, 91701, Slovakia | |
Completed | Zilina, 01001, Slovakia | |
Completed | Kosice, 04001, Slovakia | |
Withdrawn | London, SE1 6LH, United Kingdom | |
Completed | La Plata, B1900ASM, Argentina | |
Completed | Varese, 21100, Italy | |
Completed | Vilnius, LT-10207, Lithuania | |
Completed | Bardejov, 085 01, Slovakia | |
Completed | Nove Zamky, 940 01, Slovakia | |
Completed | Córdoba, X5006IKK, Argentina | |
Completed | Corrientes, 3400, Argentina | |
Withdrawn | Poprad, 058 01, Slovakia | |
Withdrawn | Lakewood, 80228, United States | |
Completed | Osaka, 530-8480, Japan | |
Completed | Sagamihara, 252-5188, Japan | |
Completed | Kagoshima, 890-8760, Japan | |
Completed | Osaka, 530-0012, Japan | |
Completed | Amagasaki, 660-8511, Japan | |
Completed | Takarazuka, 665-0873, Japan | |
Completed | Minato, 108-0073, Japan | |
Completed | Kawagoe, 350-8550, Japan | |
Completed | Covington, 70433, United States | |
Completed | Córdoba, 5000, Argentina | |
Completed | Belo Horizonte, 30140-073, Brazil | |
Completed | Campinas, 13060-080, Brazil | |
Completed | Belo Horizonte, 30110-090, Brazil | |
Withdrawn | Tubarao, 88701-160, Brazil | |
Completed | Fortaleza, 60430 370, Brazil | |
Completed | Porto Alegre, 90619900, Brazil | |
Completed | Belo Horizonte, 30140-062, Brazil | |
Withdrawn | Sao Paulo, 04005-000, Brazil | |
Completed | Rio de Janeiro, 20551-030, Brazil | |
Withdrawn | Porto Alegre, 90050-170, Brazil | |
Completed | Belo Horizonte, 30130-100, Brazil | |
Completed | Porto Alegre, Brazil | |
Withdrawn | Belo Horizonte, 30150-240, Brazil | |
Withdrawn | Belo Horizonte, 30150-221, Brazil | |
Completed | Denver, 80220, United States | |
Withdrawn | Ocala, 34471, United States | |
Withdrawn | Athens, 30606, United States | |
Withdrawn | Newark, 07102-2094, United States | |
Completed | Avondale, 85388, United States | |
Completed | VELDHOVEN, 5504 DB, Netherlands | |
Completed | London, W6 8RF, United Kingdom | |
Completed | Taoyuan, 333423, Taiwan | |
Completed | Junín, B6000BHA, Argentina | |
Completed | Ciudad Auton. de Buenos Aires, C1181ACL, Argentina | |
Completed | Clinton, 20735, United States | |
Completed | Jackson, 39216, United States | |
Completed | New York, 10011, United States | |
Withdrawn | Lawrenceville, 30046, United States | |
Completed | Aurora, 80045, United States | |
Withdrawn | Clearwater, 33756, United States | |
Withdrawn | Sioux Falls, 57117, United States | |
Withdrawn | St. Louis, 63128, United States | |
Withdrawn | Somerset, 08873, United States | |
Completed | Omihachiman, 523-0082, Japan | |
Completed | Habikino, 583-0872, Japan | |
Completed | Philadelphia, 19140, United States | |
Completed | São José do Rio Preto, 15090, Brazil | |
Completed | Curitiba, 80230-130, Brazil | |
Completed | Tatui, 18270-170, Brazil | |
Completed | Passo Fundo, 99010-080, Brazil | |
Completed | Canoas, 92200-000, Brazil | |
Completed | Santo André, 09030-010, Brazil | |
Completed | Uberlândia, 38411-186, Brazil | |
Completed | São Bernardo do Campo, 09715-090, Brazil | |
Completed | Belo Horizonte, 30110-130, Brazil | |
Completed | Sofia, 1309, Bulgaria | |
Completed | Sofia, 1309, Bulgaria | |
Completed | Matsumoto, 390-8621, Japan | |
Withdrawn | Fukuoka, 814-0001, Japan | |
Completed | Matsusaka, 515-8566, Japan | |
Completed | Shanghai, 200032, China | |
Completed | Beijing, 100730, China | |
Completed | Changsha, 410011, China | |
Completed | Tianjin, 300000, China | |
Completed | Wuhan, 430030, China | |
Withdrawn | Shanghai, 200080, China | |
Withdrawn | Nanjing, China | |
Withdrawn | Shijiazhuang, 050051, China | |
Completed | Haikou, 570311, China | |
Withdrawn | Guiyang, 550004, China | |
Completed | Qingdao, 266003, China | |
Completed | Wenzhou, 325000, China | |
Withdrawn | Wuhan, 430030, China | |
Completed | Wuhan, 430014, China | |
Completed | Bratislava 37, 833 48, Slovakia | |
Withdrawn | Kosice, 04011, Slovakia | |
Completed | Ivano-Frankivsk, 76014, Ukraine | |
Completed | Vinnytsia, 21018, Ukraine | |
Completed | Ivano-Frankivsk, 76000, Ukraine | |
Completed | Kharkiv, 61018, Ukraine | |
Completed | Kyiv, 1601, Ukraine | |
Completed | Vinnytsia, 21018, Ukraine | |
Completed | Ivano-Frankivsk, 76000, Ukraine | |
Completed | Vancouver, V5Z 1M9, Canada | |
Completed | Montreal, Quebec, H4A 3J1, Canada | |
Withdrawn | Beijing, 100730, China | |
Withdrawn | East Orange, 07918, United States | |
Withdrawn | Urbana, 61801, United States | |
Withdrawn | Tampa, 33613, United States | |
Withdrawn | Voorhees, 08043, United States | |
Withdrawn | San Diego, 92120, United States | |
Withdrawn | Providence, 02906-2895, United States | |
Withdrawn | Tullahoma, 37388, United States | |
Withdrawn | Oakbrook Terrace, 60181, United States | |
Withdrawn | Detroit, 48236, United States | |
Withdrawn | Wormleysburg, 17043, United States | |
Withdrawn | Seattle, 98122, United States | |
Withdrawn | St. Louis, 63128, United States | |
Withdrawn | Indianapolis, 46237, United States | |
Withdrawn | Ogden, 84403-3150, United States | |
Withdrawn | San Gabriel, 91776, United States | |
Withdrawn | Memphis, 38103-2897, United States | |
Completed | Vila Nova de Gaia, 4434-502, Portugal | |
Completed | Ponta Delgada, 9500-370, Portugal | |
Completed | Saitama, 336-8522, Japan | |
Completed | Tomakomai, 053-8506, Japan | |
Completed | Iasi, 700732, Romania | |
Completed | Frankfurt, 60389, Germany | |
Withdrawn | Hannover, 30625, Germany | |
Completed | Fribourg, 1700, Switzerland | |
Completed | Baden, 5404, Switzerland | |
Withdrawn | Iowa City, 52242, United States | |
Withdrawn | Jacksonville, 32216, United States | |
Withdrawn | Hammond, 70403, United States | |
Completed | Beijing, 100083, China | |
Withdrawn | Baotou, 14040, China | |
Active, not recruiting | Beijing, 100144, China | |
Withdrawn | Shanghai, 200433, China | |
Completed | Taiyuan, 030001, China | |
Completed | Guangzhou, 510080, China | |
Completed | Kyoto, 615-8256, Japan | |
Completed | Wien, 1090, Austria | |
Completed | Elk Grove Village, 60007, United States | |
Completed | Zaporizhzhya, 69600, Ukraine | |
Completed | Lviv, 79010, Ukraine | |
Completed | Changchun, 130021, China | |
Withdrawn | Lanzhou, 730030, China | |
Completed | Guangzhou, 510630, China | |
Completed | Zhangzhou, 363000, China | |
Completed | Beijing, 100053, China | |
Completed | Nanjing, 210006, China | |
Withdrawn | Shanghai, 201700, China | |
Withdrawn | Changsha, 410013, China | |
Completed | Taizhou, 317000, China | |
Completed | Guangzhou, China | |
Completed | Zhongshan, 528403, China | |
Completed | Changzhou, 213003, China | |
Completed | Zhanjiang, 524001, China | |
Completed | Xi'an, 710038, China | |
Withdrawn | Xuzhou, 221351, China | |
Withdrawn | Beijing, 100037, China | |
Withdrawn | Nanjing, 210009, China | |
Completed | Beijing, 100853, China | |
Completed | Beijing, 100029, China | |
Withdrawn | Aurora, 60504, United States | |
Withdrawn | Aurora, 60504, United States | |
Completed | Bielefeld, 33604, Germany | |
Withdrawn | Santa Rosa, 95494, United States | |
Withdrawn | Bellevue, 98004-4623, United States | |
Withdrawn | Austell, 30106-6810, United States | |
Completed | Kiev, 3680, Ukraine | |
Completed | Osaka, 558-8558, Japan | |
Completed | KORTRIJK, 8500, Belgium | |
Completed | Morioka, 020-0066, Japan | |
Completed | Shanghai, 200040, China | |
Completed | Suginami-ku, 166-0001, Japan | |
Completed | Kyoto, 604-8401, Japan | |
Completed | Tver, 170036, Russian Federation | |
Withdrawn | Napoli, 80131, Italy | |
Withdrawn | ALKMAAR, 1815 JD, Netherlands | |
Completed | Tallinn, 11312, Estonia | |
Completed | Incheon, 21565, Korea, Republic Of | |
Completed | Burgas, 8000, Bulgaria | |
Completed | Panagyurishte, 4500, Bulgaria | |
Completed | Takamatsu, 760-8557, Japan | |
Completed | Sapporo, 064-8622, Japan | |
Completed | Katowice, 40-040, Poland | |
Completed | Tartu, 50406, Estonia | |
Completed | BORDEAUX, 33000, France | |
Completed | Hsinchu City, 300, Taiwan | |
Completed | Beijing, 100730, China | |
Completed | Santa Fe, S3000FWO, Argentina | |
Withdrawn | Burgas, 8000, Bulgaria | |
Completed | Ruse, 7013, Bulgaria | |
Completed | São Paulo, 01323-903, Brazil | |
Completed | Göteborg, 413 46, Sweden | |
Completed | Linköping, 582 85, Sweden | |
Completed | Rosario, 2000, Argentina | |
Completed | Barcelona, 08035, Spain | |
Completed | Córdoba, X5000AAX, Argentina | |
Completed | Tampere, 33521, Finland | |
Completed | Hefei, 230001, China | |
Completed | Wien, 1170, Austria | |
Completed | Changsha, 410008, China | |
Completed | Helsinki, 00290, Finland | |
Completed | Fuzhou, 350025, China | |
Completed | Lublin, 20-718, Poland | |
Completed | Wroclaw, 50-981, Poland | |
Completed | Dnipro, 49000, Ukraine | |
Completed | Kawasaki, 215-0026, Japan | |
Completed | Santa Rosa, 6300, Argentina | |
Completed | Gdynia, 81-338, Poland | |
Withdrawn | Ostrava - Poruba, 702 00, Czechia | |
Active, not recruiting | Chongqing, China | |
Completed | Oulu, 90220, Finland | |
Completed | San Isidro, B1642DCD, Argentina | |
Completed | Tallinn, 13419, Estonia | |
Completed | Novosibirsk, 630055, Russian Federation | |
Completed | Novosibirsk, 630087, Russian Federation | |
Completed | Voronezh, 394066, Russian Federation | |
Active, not recruiting | Kaohsiung, 82445, Taiwan | |
Completed | St. Petersburg, 195271, Russian Federation | |
Completed | Tomsk, 634012, Russian Federation | |
Completed | St. Petersburg, 194354, Russian Federation | |
Completed | Nizhny Novgorod, 603155, Russian Federation | |
Completed | Moscow, 105077, Russian Federation | |
Completed | Ryazan, 390026, Russian Federation | |
Completed | Belgrade, 11000, Serbia | |
Completed | Rostov-on-Don, 344022, Russian Federation | |
Withdrawn | Trois-Rivieres, G8Z 3R9, Canada | |
Completed | Kemerovo, 650002, Russian Federation | |
Completed | Belgrade, 11080, Serbia | |
Completed | Belgrade, 11040, Serbia | |
Completed | Nis, 18000, Serbia | |
Completed | Moscow, 117997, Russian Federation | |
Completed | Beograd, 11000, Serbia | |
Completed | Chur, 7000, Switzerland | |
Completed | St. Petersburg, 191015, Russian Federation | |
Completed | St. Petersburg, 194291, Russian Federation | |
Completed | Moscow, 129327, Russian Federation | |
Completed | Moscow, 115682, Russian Federation | |
Completed | San Martín, 1650, Argentina | |
Withdrawn | Suzhou, China | |
Withdrawn | Quilmes, 1878, Argentina | |
Withdrawn | Wien, 1090, Austria | |
Completed | Saint-Petersburg, 197374, Russian Federation | |
Withdrawn | Lublin, 20-081, Poland | |
Withdrawn | Warszawa, 01-809, Poland | |
Withdrawn | Moscow, 129128, Russian Federation | |
Withdrawn | Odessa, 65025, Ukraine | |
Withdrawn | Kharkiv, 61176, Ukraine | |
Withdrawn | Uzhgorod, 8801, Ukraine | |
Withdrawn | Bangkok, 10310, Thailand |
Primary Outcome
- Number of participants with composite of Myocardial infarction (MI), ischemic stroke, cardiovascular death, acute limb ischemia (ALI) and major amputation due to a vascular etiologyThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with TIMI (Thrombolysis in Myocardial Infarction) Major bleedingTo evaluate the overall safety and tolerability.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionYesSafety Issue:
Secondary Outcome
- Number of participants with composite of MI, ischemic stroke, Coronary heart disease (CHD) death, ALI, and major amputation of a vascular etiologyThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with an unplanned index limb revascularization for recurrent limb ischemia (subsequent index leg revascularization that was not planned or considered as part of the initial treatment plan at the time of randomization)The analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with hospitalization for a coronary or peripheral cause (either lower limb) of a thrombotic natureThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with composite of MI, ischemic stroke, All-cause mortality (ACM), ALI, and major amputation of a vascular etiologyThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with composite of MI, all-cause stroke, Cardiovascular (CV) death, Acute limb ischemia (ALI), and major amputation of a vascular etiologyThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of mortality (all-cause)The analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with venous thromboembolic (VTE) eventsThe analysis of study efficacy outcome events will be based on events as adjudicated by the Independent Central Adjudication Committee.date_rangeTime Frame:Approximately 2 yearsenhanced_encryptionNoSafety Issue:
- Number of participants with ISTH (International Society on Thrombosis and Haemostasis) major bleedingdate_rangeTime Frame:Approximately 2 years
- Number of participants with BARC (Bleeding Academic Research Consortium) Type 3b and above bleeding eventsdate_rangeTime Frame:Approximately 2 years
Trial design
Trial Type
InterventionalIntervention Type
DrugTrial Purpose
PreventionAllocation
RandomizedBlinding
Double BlindAssignment
Parallel AssignmentTrial Arms
2