Relative Bioavailability and food effect study with finerenone
The primary objectives of the study were to
• investigate the pharmacokinetic dose proportionality of a single oral dose of 10 mg tablet in comparison to 20 mg tablet in the fasting condition
• investigate the effect of a high fat, high calorie meal on the pharmacokinetics after a single oral dose of 20 mg tablet
The secondary objective of this study was to investigate the safety and tolerability of single oral doses of finerenone.
- Healthy male white subjects, 18 to 45 years of age, BMI: ≥ 18.0 and ≤ 29.9 kg/m^2
No Exclusion Criteria Available
Relative bioavailability study to investigate the pharmacokinetic dose proportionality, safety and tolerability of single oral doses of finerenone 10 mg tablet in comparison to 20 mg tablet in the fasting condition and to investigate the effect of a high fat, high calorie meal on the 20 mg tablet in healthy male subjects in a randomized, open-label, three-fold crossover design