In previous in vitro studies it could be shown, that Dexpanthenol has an influence on the gene expression of fibroblasts. The genes which are influenced by Dexpanthenol play mainly a role during cell proliferating processes.The aim of this study is to investigate the molecular effect of Dexpanthenol on human living skin, during wound healing.
- Skin type I to IV - Willingness to avoid intensive sunlight exposure two weeks before the start of the study and at least 2 months after removal of the stitches
- Active skin disease, moles, tattoos, strong pigmentation at the test area or scars in the test area that would influence the visual scoring - History of keloids and hypertrophic scars - Frequent visits of tanning booths - Intake of drugs interfering with the immune system (e.g. antiphlogistics, corticosteroids, immunosuppressants, and antihistamines) within 30 days before day 1 as well as during the study.
Hamburg, Germany, 22869
E-mail: [email protected]
Phone: Not Available
A randomized, double-blind, single centre, placebo-controlled pilot study to assess on a molecular level the influence of a 5 % dexpanthenol ointment in subjects with previously injured skin by investigation of skin biopsies