stop_circleTerminated/Withdrawn
Hemophilia A
Bayer Identifier:
12948
ClinicalTrials.gov Identifier:
EudraCT Number:
EU CT Number:
Not Available
Joint status in subjects with severe hemophilia A in relation to different treatment regimens
Trial purpose
The joint status (knees, ankles) of patients suffering from severe Hemophilia A (too little blood clotting factor VIII in blood) is evaluated in a single magnetic resonance imaging session. No study medication is given.
Key Participants Requirements
Sex
MaleAge
12 - 35 YearsTrial summary
Enrollment Goal
156Trial Dates
June 2009 - December 2010Phase
Phase 4Could I Receive a placebo
NoProducts
No DrugAccepts Healthy Volunteer
NoWhere to participate
Status | Institution | Location |
---|---|---|
Completed | Medizinische Einrichtungen der Universität Bonn | Bonn, 53105, Germany |
Completed | Kurpfalzkrankenhaus Heidelberg gGmbH | Heidelberg, 69123, Germany |
Completed | Praxis für Innere Medizin u. Gefäßkrankheiten HBE | Magdeburg, 39112, Germany |
Terminated | Kent & Canterbury Hospital | Canterbury, CT1 3NG, United Kingdom |
Completed | Royal Free Hospital | London, NW3 2QG, United Kingdom |
Completed | A.O.U. di Parma | Parma, 43100, Italy |
Completed | Karolinska Universitetssjukhuset i Solna | Stockholm, 171 76, Sweden |
Completed | Hippokrateion University General Hospital of Athens | Athens, 115 27, Greece |
Completed | Praxis Hr. Dr. H. Pollmann | Münster, 48143, Germany |
Completed | IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico | Milano, 20122, Italy |
Completed | Azienda Policlinico Umberto I | Roma, 00161, Italy |
Completed | A.O. di Padova | Padova, 35128, Italy |
Completed | Hospital Universitari i Politècnic La Fe | Valencia, 46026, Spain |
Completed | Complejo Hospitalario Universitario A Coruña | A Coruña, 15006, Spain |
Completed | Skånes Universitetssjukhus Malmö | Malmö, 205 02, Sweden |
Completed | Laiko General Hospital of Athens | Athens, 115 27, Greece |
Primary Outcome
- Maximum ankle MRI scoredate_rangeTime Frame:no timeframe (single visit, "snapshot" of the actual joint status)enhanced_encryptionnoSafety Issue:
Secondary Outcome
- Total MRI score of the maximum index jointdate_rangeTime Frame:no timeframe (single visit, "snapshot" of the actual joint status)enhanced_encryptionnoSafety Issue:
- Number of bleeds in each index joint over previous 5 yearsdate_rangeTime Frame:no timeframe (medical history status)enhanced_encryptionnoSafety Issue:
- Number of total joint bleeds and their locations over previous 5 yearsdate_rangeTime Frame:no timeframe (medical history status)enhanced_encryptionnoSafety Issue:
- Physical joint score (Gilbert Score)date_rangeTime Frame:no timeframe (single visit, "snapshot" of the actual joint status)enhanced_encryptionnoSafety Issue:
Trial design
Trial Type
InterventionalIntervention Type
Procedure/SurgeryTrial Purpose
DiagnosticAllocation
Non-randomizedBlinding
Single BlindAssignment
Parallel AssignmentTrial Arms
5