Trial Condition(s):

Hypertension, Pulmonary

BAY63-2521:Long-term extension study in patients with pulmonary arterial hypertension (PATENT-2)

Bayer Identifier:

12935

ClinicalTrials.gov Identifier:

NCT00863681

EudraCT Number:

2008-003610-94

Study Completed

Trial Purpose

Patients who have completed the 12 weeks treatment of the PATENT-1 trial (study number 12934) will be asked to participate in this long term extension study with BAY63-2521.

Inclusion Criteria
- Patients who have completed 12 weeks of 
treatment in the double blind trial PATENT 1
Exclusion Criteria
- Patients who have an ongoing serious adverse event from PATENT 1 that is  assessed as related to BAY63-2521 are not allowed to participate in the extension trial.

Trial Summary

Enrollment Goal
396
Trial Dates
black-arrow
Phase
3
Could I receive a placebo?
No
Products
Adempas (Riociguat, BAY63-2521)
Accepts Healthy Volunteers
No

Where to Participate

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Locations
Status
LocationsStatus
Locations

Investigative Site

Homburg, Germany, 66421

Status
Completed
 
Locations

Investigative Site

Gießen, Germany, 35392

Status
Completed
 
Locations

Investigative Site

Leipzig, Germany, 04103

Status
Completed
 
Locations

Investigative Site

Köln, Germany, 50924

Status
Completed
 
Locations

Investigative Site

Fairfield, United States, 45014

Status
Completed
 
Locations

Investigative Site

Sacramento, United States, 95817

Status
Completed
 
Locations

Investigative Site

Dallas, United States, 75390-9252

Status
Completed
 
Locations

Investigative Site

München, Germany, 81377

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01307

Status
Completed
 
Locations

Investigative Site

Hannover, Germany, 30625

Status
Completed
 
Locations

Investigative Site

Heidelberg, Germany, 69126

Status
Completed
 
Locations

Investigative Site

Greifswald, Germany, 17475

Status
Completed
 
Locations

Investigative Site

Cambridge, United Kingdom, CB23 3RE

Status
Completed
 
Locations

Investigative Site

London, United Kingdom, NW3 2QG

Status
Completed
 
Locations

Investigative Site

Clydebank, United Kingdom, G81 4DY

Status
Completed
 
Locations

Investigative Site

Aurora, United States, 80045

Status
Completed
 
Locations

Investigative Site

Boston, United States, 02111

Status
Completed
 
Locations

Investigative Site

Lille Cedex, France, 59037

Status
Completed
 
Locations

Investigative Site

Bunkyo-ku, Japan, 113-8655

Status
Completed
 
Locations

Investigative Site

Nagoya, Japan, 467-8602

Status
Completed
 
Locations

Investigative Site

Kanazawa, Japan, 920-8641

Status
Completed
 
Locations

Investigative Site

Hiroshima, Japan, 734-8511

Status
Completed
 
Locations

Investigative Site

Tsukuba, Japan, 305-8576

Status
Completed
 
Locations

Investigative Site

Toride, Japan, 302-0022

Status
Completed
 
Locations

Investigative Site

Trieste, Italy, 34149

Status
Completed
 
Locations

Investigative Site

Boston, United States, 02114

Status
Completed
 
Locations

Investigative Site

Columbus, United States, 43221

Status
Completed
 
Locations

Investigative Site

Cleveland, United States, 44195

Status
Completed
 
Locations

Investigative Site

Los Angeles, United States, 90073

Status
Completed
 
Locations

Investigative Site

BREST, France, F-29609

Status
Completed
 
Locations

Investigative Site

MONTPELLIER, France, 34059

Status
Completed
 
Locations

Investigative Site

GRENOBLE Cedex 09, France, 38043

Status
Completed
 
Locations

Investigative Site

Otwock, Poland, 05-400

Status
Completed
 
Locations

Investigative Site

Sendai, Japan, 980-8574

Status
Completed
 
Locations

Investigative Site

BRUXELLES - BRUSSEL, Belgium, 1070

Status
Completed
 
Locations

Investigative Site

LEUVEN, Belgium, 3000

Status
Completed
 
Locations

Investigative Site

Mexico D.F., Mexico, 14080

Status
Completed
 
Locations

Investigative Site

Culiacan, Mexico, 80020

Status
Completed
 
Locations

Investigative Site

Umeå, Sweden, 901 85

Status
Completed
 
Locations

Investigative Site

Aarhus N, Denmark, 8200

Status
Completed
 
Locations

Investigative Site

Praha 2, Czech Republic, 12808

Status
Completed
 
Locations

Investigative Site

Shinjuku-ku, Japan, 160-8582

Status
Completed
 
Locations

Investigative Site

Ota-ku, Japan, 143-8541

Status
Completed
 
Locations

Investigative Site

Okayama, Japan, 701-1192

Status
Completed
 
Locations

Investigative Site

Tomigusuku, Japan, 901-0243

Status
Completed
 
Locations

Investigative Site

Kobe, Japan, 650-0017

Status
Completed
 
Locations

Investigative Site

Mitaka, Japan, 181-8611

Status
Completed
 
Locations

Investigative Site

Pavia, Italy, 27100

Status
Completed
 
Locations

Investigative Site

Roma, Italy, 00161

Status
Completed
 
Locations

Investigative Site

Milano, Italy, 20123

Status
Completed
 
Locations

Investigative Site

DARLINGHURST, Australia, 2010

Status
Completed
 
Locations

Investigative Site

Chermside, Australia, 4032

Status
Completed
 
Locations

Investigative Site

PRAHRAN, Australia, 3181

Status
Completed
 
Locations

Investigative Site

HOBART, Australia, 7000

Status
Completed
 
Locations

Investigative Site

Coimbra, Portugal, 3000-075

Status
Completed
 
Locations

Investigative Site

São Paulo, Brazil, 04012 180

Status
Completed
 
Locations

Investigative Site

Montreal, Canada, H3T 1E2

Status
Completed
 
Locations

Investigative Site

Calgary, Canada, T1Y 6J4

Status
Completed
 
Locations

Investigative Site

Monterrey, Mexico, 64020

Status
Completed
 
Locations

Investigative Site

Auchenflower, Australia, 4066

Status
Completed
 
Locations

Investigative Site

Wien, Austria, 1090

Status
Completed
 
Locations

Investigative Site

Innsbruck, Austria, 6020

Status
Completed
 
Locations

Investigative Site

Linz, Austria, 4020

Status
Completed
 
Locations

Investigative Site

Ankara, Turkey

Status
Completed
 
Locations

Investigative Site

Izmir, Turkey, 35-100

Status
Completed
 
Locations

Investigative Site

Istanbul, Turkey, 34098

Status
Completed
 
Locations

Investigative Site

Rio de Janeiro, Brazil, 21941-913

Status
Completed
 
Locations

Investigative Site

Shanghai, China, 200433

Status
Completed
 
Locations

Investigative Site

Shanghai, China, 200032

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 06351

Status
Completed
 
Locations

Investigative Site

Zürich, Switzerland, 8091

Status
Completed
 
Locations

Investigative Site

Taipei, Taiwan, China, 10016

Status
Completed
 
Locations

Investigative Site

Singapore, Singapore, 119228

Status
Completed
 
Locations

Investigative Site

Chaidari, Greece, 124 62

Status
Completed
 
Locations

Investigative Site

Porto Alegre, Brazil, 90020 090

Status
Completed
 
Locations

Investigative Site

São Paulo, Brazil, 04020-050

Status
Completed
 
Locations

Investigative Site

Moscow, Russia, 121552

Status
Completed
 
Locations

Investigative Site

St. Petersburg, Russia, 197341

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100037

Status
Completed
 
Locations

Investigative Site

Guangzhou, China, 510100

Status
Completed
 
Locations

Investigative Site

Beijing, China, 100020

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 05505

Status
Completed
 
Locations

Investigative Site

Taipei, Taiwan, China, 11217

Status
Completed
 
Locations

Investigative Site

Kaoshiung, Taiwan, China, 81346

Status
Completed
 
Locations

Investigative Site

Singapore, Singapore, 168752

Status
Completed
 
Locations

Investigative Site

Rouen, France, 76031

Status
Completed
 
Locations

Investigative Site

El Paso, United States, 79902

Status
Completed
 
Locations

Investigative Site

Capital Federal, Argentina

Status
Completed
 
Locations

Investigative Site

Seoul, South Korea, 03722

Status
Completed
 
Locations

Investigative Site

Omaha, United States, 68131

Status
Completed
 
Locations

Pulmocritic

Guadalajara, Mexico, 44670

Status
Terminated
 
Locations

Antiguo Hospital Civil de Guadalajara "Fray Antonio Alcalde"

Guadalajara, Mexico, 44280

Status
Terminated
 
Locations

Investigative Site

Querétaro, Mexico, 38000

Status
Completed
 
Locations

Investigative Site

Chiang Mai, Thailand, 50200

Status
Completed
 
Locations

Investigative Site

Lisboa, Portugal, 1169-024

Status
Completed
 
Locations

Centro Hospitalar de Lisboa Norte - Hospital Santa Maria

Lisboa, Portugal, 1649-035

Status
Active, not recruiting
 
Locations

Investigative Site

Bangkok, Thailand, 10330

Status
Completed
 
Locations

Investigative Site

Pessac, France, 33604

Status
Completed
 
Locations

Investigative Site

BESANCON, France, 25030

Status
Completed
 

Trial Design