Trial Condition(s):

Atrial Fibrillation

Efficacy and Safety of Rivaroxaban for the Prevention of Stroke in Subjects With Non-Valvular Atrial Fibrillation

Bayer Identifier:

12620

ClinicalTrials.gov Identifier:

NCT00494871

EudraCT Number:

Not Available

EU CT Number:

Not Available

Study Completed

Trial Purpose

This is a clinical study evaluating the efficacy and safety of rivaroxaban for stroke prevention in patients with atrial fibrillation (originally described in Japanese).

Inclusion Criteria
- 20 years or older
 - Japanese male or female
 - Non- valvular atrial fibrillation documented by ECG
 - Patients with a risk of stroke and non-CNS systemic embolism
Exclusion Criteria
- Significant mitral stenosis
 - Patients in whom anticoagulants are contraindicated

Trial Summary

Enrollment Goal
1280
Trial Dates
black-arrow
Phase
3
Could I receive a placebo?
Yes
Products
Xarelto (Rivaroxaban, BAY59-7939)
Accepts Healthy Volunteers
No

Where to Participate

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Locations
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Kihara Cardiovascular and Internal Hospital

Asahikawa, Japan, 078-8214

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Nikko Memorial Hospital

Muroran, Japan, 051-8501

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Hakodate Goryoukaku Hospital

Hakodate, Japan, 040-8611

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Seihoku Chuo Hospital

Goshogawara, Japan, 037-0053

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General Hanamaki Hospital

Hanamaki, Japan, 025-0075

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Sendai East Neurosurgical Hospital

Sendai, Japan, 983-0821

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Tohoku Kosai Hospital

Sendai, Japan, 980-0803

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Namegata District General Hospital

Namegata, Japan, 311-3516

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Kinu Medical Association Hospital

Joso, Japan, 303-0016

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Maebashi Red Cross Hospital

Mebashi, Japan, 371-0014

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Saitama National Hospital

Wako, Japan, 351-0102

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Kitasato University Medeical Center

Kitamoto, Japan, 364-8501

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Saino Clinic

Tokorozawa, Japan, 359-1141

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Asahi Central Hospital

Asahi, Japan, 289-2511

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Kitahara Neurosurgical Institute

Hachioji, Japan, 192-0045

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Tenshi Hospital

Sapporo, Japan, 065-8611

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Sapporo Minami-ichijo Hospital

Sapporo, Japan, 060-0061

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Miyanomori Memorial Hospital

Sapporo, Japan, 064-8570

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Oji General Hospital

Tomakomai, Japan, 053-8506

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Sendai Medical Center

Sendai, Japan, 983-8520

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Mito Medical Center

Higashiibaraki, Japan, 311-3193

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Ibaraki Prefectural Central Hospital

Kasama, Japan, 309-1793

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Aida Kinen Rehabilitation Hospital

Moriya, Japan, 302-0112

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Tokorozawa Heart Center

Tokorozawa, Japan, 359-1142

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Itabashi Medical Association Hospital

Itabashi-ku, Japan, 175-0082

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Tokyo Heart Center

Shinagawa-ku, Japan, 141-0001

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Kanagawa Cardiovascular and Respiratory Center

Yokohama, Japan, 236-0051

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Tachikawa General Hospital

Nagaoka, Japan, 940-8621

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Toyama University Hospital

Toyama, Japan, 930-0194

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Suwa Red Cross Hospital

Suwa, Japan, 392-8510

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Saigata National Hospital

Joetsu, Japan, 949-3193

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Komoro Kosei General Hospital

Komoro, Japan, 384-8588

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Ogaki Municipal Hospital

Ogaki, Japan, 503-8502

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Fukuroi Municipal Hospital

Fukuroi, Japan, 437-0061

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Seirei Mikatahara General Hospital

Hamamatsu, Japan, 433-8558

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Social Insurance Chukyo Hospital

Nagoya, Japan, 457-8510

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Nagoya Ekisaikai Hospital

Nagoya, Japan, 454-8502

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Kanazawa Medical Center

Kanazawa, Japan, 920-8650

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Takatsuki Red Cross Hospital

Takatsuki, Japan, 569-1096

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Sakurabashi Watanabe Hospital

Osaka, Japan, 530-0001

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Higashiosaka City General Hospital

Higashiosaka, Japan, 578-8588

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Osaka-Minami Medical Center

Kawachinagano, Japan, 586-8521

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Yoshida Hospital

Kobe, Japan, 652-0803

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Japanese Red Cross Okayama Hospital

Okayama, Japan, 700-8607

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Ehime National Hospital

Toon, Japan, 791-0281

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Sumitomo Besshi Hospital

Niihama, Japan, 792-8543

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Fujinomiya City General Hospital

Fujinomiya, Japan, 418-0076

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Iwata City Hospital

Iwata, Japan, 438-8550

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Shimada Municipal Hospital

Shimada, Japan, 427-8502

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Nagoya Daiichi Red Cross Hospital

Nagoya, Japan, 453-8511

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Kuwana City Hospital-Branch Hospital

Kuwana, Japan, 511-0068

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Houju Kinen Hospital

Nomi, Japan, 923-1100

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Tsushima Clinic

Toyonaka, Japan, 560-0022

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Hanwa Memorial Hospital

Osaka, Japan, 558-0011

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Kobe Red Cross Hospital

Kobe, Japan, 651-0073

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Tottori Medical Center

Tottori, Japan, 689-0203

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Health insurance Naruto Hospital

Naruto, Japan, 772-8503

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Kawashima Cardiovascular Clinic

Tokushima, Japan, 770-0011

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Ehime Prefectural Central Hospital

Matsuyama, Japan, 790-0024

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Murakami Kinen Hospital

Saijo, Japan, 793-0030

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Imabari Hospital

Imabari, Japan, 799-1592

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Kyushu Kosei Nenkin Hospital

Kitakyushu, Japan, 806-8501

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Go Neurosurgery Clinic

Chikushi-gun, Japan, 811-1244

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Shinkoga Hospital

Kurume, Japan, 830-8577

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Kumamoto Medical Center

Kumamoto, Japan, 860-0008

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Hashino Department of Circulatory System Internal Medicine

Kagoshima, Japan, 891-0116

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Shonai Amarume Hospital

Higashikawada, Japan, 999-7782

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Chiba Tokushukai Hospital

Funabashi, Japan, 274-8503

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Shonan Kamakura General Hospital

Kamakura, Japan, 247-8533

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Shonan Fujisawa Tokushukai Hospital

Fujisawa, Japan, 251-0041

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Shizuoka Tokushukai Hospital

Shizuoka, Japan, 421-0193

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Nagoya Tokushukai Genaral Hospital

Kasugai, Japan, 487-0013

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Uji Tokushukai Hospital

Uji, Japan, 611-0042

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Nozaki Tokushukai Hospital

Daito, Japan, 574-0074

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Kishiwada Tokushukai Hospital

Kishiwada, Japan, 596-8522

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Kasaoka Daiichi Hospital

Kasaoka, Japan, 714-0043

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Hirakata kohsai Hospital

Hirakata, Japan, 573-0153

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Yame Rihabiri Hospital

Yame, Japan, 834-0006

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Shinkomonji Hospital

Kitakyushu, Japan, 800-0057

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Fukuoka Wajiro Hospital

Fukuoka, Japan, 811-0213

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Fukuoka University Hospital

Fukuoka, Japan, 814-0180

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Fukuoka University Chikushi Hospital

Chikushino, Japan, 818-8502

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Shimada Hospital

Ogori, Japan, 838-0141

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Yano Cardiovascular Medicine Intarnal Medicine Clinic

Fukuoka, Japan, 813-0044

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Higuchi Hospital

Kasuga, Japan, 816-0833

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Nagasaki Municipal Hospital

Nagasaki, Japan, 850-8555

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Nakamura Memorial Hospital

Sapporo, Japan, 060-8570

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Oita Medical Center

Oita, Japan, 870-0263

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Fukuoka Tokushukai Medical Center

Kasuga, Japan, 816-0864

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ChubuTokushukai Hospital

Okinawa, Japan, 904-8585

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Izumi Medical Center

Izumi, Japan, 899-0131

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Takanoko Hospital

Matsuyama, Japan, 790-0925

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Chibanishi General Hospital

Matsudo, Japan, 270-2251

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Kitano Hospital

Osaka, Japan, 530-8480

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Wakayama Rosai Hospital

Wakayama, Japan, 640-8505

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Riverside Clinic

Sapporo, Japan, 064-0807

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Chitose Houyukai Hospital

Chitose, Japan, 066-0034

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Hirosaki National Hospital

Hirosaki, Japan, 036-8545

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Toho University Ohashi Medical Center

Meguro-ku, Japan, 153-8515

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Fukui General Clinic

Fukui, Japan, 910-0067

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Shizuoka City Shimizu Hospital

Shizuoka, Japan, 424-8636

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KKR Takamatsu Hospital

Takamatsu, Japan, 760-0018

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Oita University Hospital

Yufu, Japan, 879-5593

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Matsuzono Second Hospital

Morioka, Japan, 020-0103

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Nanbu Tokushukai Hospital

Shimajiri, Japan, 901-0493

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Saiseikai Futsukaichi Hospital

Chikushino, Japan, 818-8516

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Ebara Hospital

Ota-ku, Japan, 145-0065

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Kusatsu General Hospital

Kusatsu, Japan, 525-8585

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Otaru Hospital

Otaru, Japan, 047-8510

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Hoshigaoka Koseinenkin Hospital

Hirakata, Japan, 573-8511

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Aizawa Hospital

Matsumoto, Japan, 390-8510

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Kyoto Second Red Cross Hospital

Kyoto, Japan, 602-8026

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Osaka General Medical Center

Osaka, Japan, 558-8558

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Sunagawa City Medical Center

Sunagawa, Japan, 073-0196

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Chubu Rosai Hospital

Nagoya, Japan, 455-8530

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Hiroshima-Nishi Medical Center

Otake, Japan, 739-0696

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Osaka National Hospital

Osaka, Japan, 540-0006

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Sendai Cardiovascular Center

Sendai, Japan, 981-3107

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Hitachi General Hospital

Hitachi, Japan, 317-0077

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Nippon Medical School Chiba Hokusoh Hospital

Imba, Japan, 270-1694

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Yotsukaidou Tokushukai Hospital

Yotsukaido, Japan, 284-0032

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Yokohama Minami Kyousai Hospital

Yokohama, Japan, 236-0037

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Shonan Atsugi Hospital

Atsugi, Japan, 243-8551

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Saiseikai Matsuyama Hospital

Matsuyama, Japan, 791-8026

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Inoue Cardiovascular Clinic

Oita, Japan, 870-0917

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Hanyu General Hospital

Hanyu, Japan, 348-8505

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Tachibanadai Hospital

Yokohama, Japan, 227-0046

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Tohoku KoseiNenkin Hospital

Sendai, Japan, 983-8512

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Tokuyama Central Hospital

Shunan, Japan, 745-8522

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Inobefunai Clinic

Oita, Japan, 870-0021

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Yokohama City Minato Red Cross Hospital

Yokohama, Japan, 231-8682

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National Center for Global Health and Medicine Hospital

Shinjuku-ku, Japan, 162-8655

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Shakaihoken Kobe Central Hospital

Kobe, Japan, 651-1145

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JA Kochi Hospital

Nangoku, Japan, 783-8509

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Kagawa Rosai Hospital

Marugame, Japan, 763-8502

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Okayama University Hospital

Okayama, Japan, 700-8558

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St. Marianna University of School Medicine Hospital

Kawasaki, Japan, 216-8511

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Nihon University Itabashi Hospital

Itabashi-ku, Japan, 173-8610

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Hashimoto Internal Medicine

Gifu, Japan, 500-8225

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Hata Hospital

Beppu, Japan, 874-0901

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Okazaki City Hospital

Okazaki, Japan, 444-8553

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Sapporo Higashi Tokushukai Hospital

Sapporo, Japan, 065-0033

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Shin-Sapporo Cardiological Hospital

Sapporo, Japan, 004-0052

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Shuwa General Hospital

Kasukage, Japan, 344-0035

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JR Sapporo Hospital

Sapporo, Japan, 060-0033

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Shimonoseki Kosei Hospital

Shimonoseki, Japan, 750-0061

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Beppu Medical Center

Beppu, Japan, 874-0011

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Close To You EST Clinic

Hirosaki, Japan, 036-8082

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Yagi Neurosurgery Hospital

Osaka, Japan, 537-0011

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Oita Oka Hospital

Oita, Japan, 870-0192

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Takiyama Hospital

Higashikurume, Japan, 203-0033

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Hamamatsu Medical Center

Hamamatsu, Japan, 432-8580

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Shin Tokyo Clinic

Matsudo, Japan, 271-0077

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Kusaba Internal and CV Hp

Yame, Japan, 834-0004

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Aishin Memorial Hospital

Sapporo, Japan, 065-0027

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Shizuoka Saiseikai General Hospital

Shizuoka, Japan, 422-8527

Locations

Okuma Hospital

Nagoya, Japan, 462-0825

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Gunma University Hospital

Maebashi, Japan, 371-8511

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Tokyo Metoropolitan Hiroo Hospital

Shibuya-ku, Japan, 150-0013

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Yao Tokushukai General Hospital

Yao, Japan, 581-0011

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Medical Plaza Edogawa

Edogawa-ku, Japan, 133-0052

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Fujisawa City Hospital

Fujisawa, Japan, 251-8550

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Kyushu Medical Center

Fukuoka, Japan, 810-8563

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JA Toride Medical Center

Toride, Japan, 302-0022

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Southern Tohoku Medical Clinic

Koriyama, Japan, 963-8052

Trial Design