stop_circleTerminated/Withdrawn

Chronic Stable Angina

Bayer Identifier:

12484

ClinicalTrials.gov Identifier:

NCT00518921

EudraCT Number:

Not Available

EU CT Number:

Not Available
Capadenoson in Angina Pectoris

Trial purpose

This is a multi-center and multi-national,randomized, double blind, placebo-controlled, 28-day treatment study with BAY 68-4986 taken orally or a matching placebo.

Key Participants Requirements

Sex

Both

Age

35 - 75 Years
  • - The primary diagnosis is chronic stable angina of mild-moderate intensity as defined by the Canadian Cardiovascular Society Functional Class II-III, in the presence of definitive coronary artery disease.
    - Male or female subjects aged 35 to 75 years (if female, only if postmenopausal or permanently sterilized)
    - Stable angina of mild-moderate intensity (Canadian class II-III) with anti-anginal medication not changed for the last 5 weeks
  • - Inability to withdraw current anti-anginal therapy
    - Inability to withdraw any concomitant therapy that would interfere with interpretation of study results

Trial summary

Enrollment Goal
0
Trial Dates
March 2008 - November 2008
Phase
Phase 2
Could I Receive a placebo
Yes
Products
Capadenoson (BAY68-4986)
Accepts Healthy Volunteer
No

Where to participate

StatusInstitutionLocation
Terminated
SP Szpital Kliniczny nr 7 Slaskiego Uniwersytetu MedycznegoKatowice, 40-635, Poland
Terminated
SP Szpital Kliniczny nr 7 Slaskiego Uniwersytetu MedycznegoKatowice, 40-635, Poland
Terminated
IV Wojskowy Szpital Kliniczny z Poliklinika, SPZOZWroclaw, 50-981, Poland
Terminated
SP Szpital Kliniczny nr 2 PAMSzczecin, 70-111, Poland
Terminated
Szpital Praski p.w.Przemienienia Panskiego , SPZOZWarszawa, 03-401, Poland
Terminated
Centrum Medycyny Ratunkowej -Dolnoslaski Szpital Specjal.Wroclaw, 50-420, Poland
Not yet recruiting
AULSS 12 Veneziana - VenetoMestre, 30174, Italy
Not yet recruiting
ASS 1 Triestina - FiuliTrieste, 34100, Italy
Not yet recruiting
Poliklinika LIPA centrumPraha 13, 158 00, Czech Republic
Not yet recruiting
Fakultni nemocnice s poliklinikou OstravaOstrava, 708 52, Czech Republic
Not yet recruiting
Fakultni nemocnice u sv. AnnyBrno, 656 91, Czech Republic
Not yet recruiting
Kromerizska nemocnice a.s.Kromeriz, 767 55, Czech Republic
Not yet recruiting
Rebecca Sieff Hospital SafedSafed, 13100, Israel
Not yet recruiting
Bacs-Kiskun Country HospitalKecskemet, 6000, Hungary
Terminated
SP Szpital Kliniczny AM w BialymstokuBialystok, 15-276, Poland
Terminated
Wojewodzki Szpital Specjalistyczny im. BieganskiegoLodz, 91-347, Poland
Terminated
Uniwersyteckie Centrum KliniczneGdansk, 80-952, Poland
Terminated
Szpital Uniwersytecki CMUJKrakow, 30-501, Poland
Terminated
Szpital Morski im. PCKGdynia, 81-519, Poland
Terminated
Specjalistyczny Szpital Sw. JanaStarogard Gdanski, 83-200, Poland
Terminated
Wojewodzki Szpital SpecjalistycznyLegnica, 59-220, Poland
Not yet recruiting
Istituto di Cura Città di PaviaPavia, 27100, Italy
Not yet recruiting
IRCCS Policlinico San MatteoPavia, 27100, Italy
Not yet recruiting
A.O.U. San MartinoGenova, 16132, Italy
Not yet recruiting
ASL Prov Pavia - LombardiaPavia, 27100, Italy
Not yet recruiting
Ustredni vojenska nemocnice PrahaPraha 6, 169 02, Czech Republic
Not yet recruiting
Fakultni nemocnice PlzenPlzen, 30599, Czech Republic
Not yet recruiting
Fakultni Nemocnice OlomoucOlomouc, 775 20, Czech Republic
Not yet recruiting
Fakultni nemocnice u sv. AnnyBrno, 656 91, Czech Republic
Not yet recruiting
Borsod County HospitalMiskolc, 3526, Hungary
Not yet recruiting
University of Pecs, Medical & Health Science CenterPecs, 7624, Hungary
Not yet recruiting
Faculty Hospital with PolyclinicNove Zamky, 940 34, Slovakia
Not yet recruiting
Kardiocentrum Nitra s.r.o.Nitra, 949 01, Slovakia
Not yet recruiting
Cardioconsult s.r.o.Bratislava, 811 04, Slovakia
Not yet recruiting
Nemocnice TGM HodoninHodonin, 695 26, Czech Republic
Not yet recruiting
Hillel Yaffe Medical CenterHadera, 38100, Israel
Not yet recruiting
Kaplan Medical CenterRehovot, 76100, Israel
Not yet recruiting
Zala Megyei KorhazZalaegerszeg, 8900, Hungary
Not yet recruiting
Allami SzivkorhazBalatonfured, 8230, Hungary
Not yet recruiting
Fakultna nemocnica Stare MestoBratislava, 813 69, Slovakia

Primary Outcome

  • Total exercise time
    date_rangeTime Frame:
    28 days for ETT and 42 days for safety
    enhanced_encryption
    Safety Issue:
    no

Secondary Outcome

  • Time to angina onset
    date_rangeTime Frame:
    28 days
    enhanced_encryption
    Safety Issue:
    no

Trial design

Phase IIa Efficacy and Safety Trial of capadenoson in Patients with Chronic Stable Angina
Trial Type
Interventional
Intervention Type
Drug
Trial Purpose
Treatment
Allocation
Randomized
Blinding
Double Blind
Assignment
Parallel Assignment
Trial Arms
4

Additional Information

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