Trial Condition(s):

Moderate Risk of CVD

A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease (ARRIVE)

Bayer Identifier:

12198

ClinicalTrials.gov Identifier:

NCT00501059

EudraCT Number:

2006-003622-29

Study Completed

Trial Purpose

The use of acetylsalicylic acid in the primary prevention of cardiovascular events has been extensively studied but to a lesser extent in patients with moderate levels of cardiovascular risk. The current study is designed to prove the efficacy and tolerability of 100 mg enteric-coated Aspirin versus placebo in the prevention of cardiovascular disease (CVD) events, which include fatal and nonfatal myocardial infarction, fatal and nonfatal stroke and CV death, in a population with no history of known CVD who are at moderate risk of major CHD events (approximately 10-20% 10 year CHD risk). This corresponds to a patient population mean 10-year CVD risk of approximately 30%. Subjects are treated in a standard care setting and may receive treatment for the underlying risk factors as defined by the treating physician. Outcome events will be adjudicated by an Endpoint Adjudication Committee and the study will be monitored by an independent Data Safety Monitoring Board.

Inclusion Criteria
- Males aged 55 years and above with 2 to 4 risk factors. Male Risk Factors:
 -- Elevated cholesterol (Tchol>200 mg/dL or LDL>130 mg/dL; as measured at screening) irrespective of current treatment
 -- Current smoking: defined as any cigarette smoking in the past 12 months
 -- Low HDL cholesterol (HDL<40 mg/dL; as measured at screening)
 -- Elevated blood pressure (SBP>140 mmHg; as measured at screening) 
 -- Currently on any medication to treat high blood pressure
 -- Positive family history of early CHD (a first-degree relative [father, mother, brother, sister, son, daughter] suffered a heart attack [myocardial infarction] before the age of 60 years)
 - Females aged 60 and above with 3 or more risk factors. Female Risk Factors:
 -- Elevated cholesterol (Tchol>240 mg/dL or LDL>160 mg/dL; as measured at screening) irrespective of current treatment
 -- Current smoking:  defined as any cigarette smoking in the past 12 months
 -- Low HDL cholesterol (HDL<40 mg/dL; as measured at screening)
 -- Elevated blood pressure (SBP>140 mmHg; as measured at screening)
 -- Currently on any medication to treat high blood pressure
 -- Positive family history of early CHD (a first-degree relative [father, mother, brother, sister, son, daughter] suffered a heart attack [myocardial infarction] before the age of 60 years)
 - An understanding and willingness to comply with trial procedures and has given written informed consent to participate in the trial
Exclusion Criteria
- History of a documented vascular event, such as MI, stroke, coronary artery angioplasty or stenting, coronary artery bypass graft, relevant arrhythmias, or congestive heart failure or vascular intervention
 - Patients who are at higher than moderate risk on the basis of their diabetes status, other factors known to the investigator, or the currently used national risk score 
 - Known contraindications to the study drug, e.g. hypersensitivity to acetylsalicylic acid
 - Recent (in the past year) history of gastrointestinal or genitourinary bleeding or other bleeding disorders
 - Active diagnosed and documented reflux esophagitis
 - Patients presenting with any medical condition, or psychiatric or substance abuse disorder, that, in the opinion of the investigator, is likely to affect the patient's ability to complete the study or precludes the patient's participation in the study
 - Lactating women or women of childbearing potential
 - Severe liver disease or damage based on the clinical judgment of the investigator
 - Severe renal disease or damage based on the clinical judgement of the investigator
 - A definite indication for acetylsalicylic acid therapy, other antiplatelet drug, or anticoagulant in the opinion of the physician
 - A history of asthma induced by administration of salicylates or substances with a similar action, notably NSAIDS
 - Chronic, frequent (> 5 days/month) use of NSAIDs (including aspirin, or aspirin containing products), COX-2 inhibitors or metamizole
 - Current participation in any other trials involving investigational products within 30 days prior to the Screening Visit
 - Current use of an anticoagulant medication
 - Sitting systolic blood pressure greater than 170 mmHg

Trial Summary

Enrollment Goal
12546
Trial Dates
black-arrow
Phase
3
Could I receive a placebo?
Yes
Products
Aspirin (Acetylsalicylic Acid, BAYE4465)
Accepts Healthy Volunteers
No

Where to Participate

Loading...
Locations
Status
LocationsStatus
Locations

Investigative Site

Arnsberg, Germany, 59757

Status
Completed
 
Locations

Investigative Site

Apolda, Germany, 99510

Status
Completed
 
Locations

Investigative Site

Magdeburg, Germany, 39104

Status
Completed
 
Locations

Investigative Site

Bergkamen, Germany, 59192

Status
Completed
 
Locations

Investigative Site

Bad Lippspringe, Germany, 33175

Status
Completed
 
Locations

Investigative Site

Nassau, Germany, 56377

Status
Completed
 
Locations

Investigative Site

Winsen, Germany, 21423

Status
Completed
 
Locations

Investigative Site

Deggingen, Germany, 73326

Status
Completed
 
Locations

Investigative Site

Köln, Germany, 51069

Status
Completed
 
Locations

Investigative Site

Gransee, Germany, 16775

Status
Completed
 
Locations

Investigative Site

Viersen, Germany, 41751

Status
Completed
 
Locations

Investigative Site

Wetter, Germany, 35083

Status
Completed
 
Locations

Investigative Site

Lienen, Germany, 49536

Status
Completed
 
Locations

Investigative Site

Bad Salzuflen, Germany, 32105

Status
Completed
 
Locations

Investigative Site

Stuhr, Germany, 28816

Status
Completed
 
Locations

Investigative Site

Arzberg, Germany, 95659

Status
Completed
 
Locations

Investigative Site

Frankfurt, Germany, 60599

Status
Completed
 
Locations

Investigative Site

Bad Bramstedt, Germany, 24576

Status
Completed
 
Locations

Investigative Site

Löhne, Germany, 32584

Status
Completed
 
Locations

Investigative Site

Hamm, Germany, 59069

Status
Completed
 
Locations

Investigative Site

Essen, Germany, 45136

Status
Completed
 
Locations

Investigative Site

Wardenburg, Germany, 26203

Status
Completed
 
Locations

Investigative Site

Lippetal, Germany, 59510

Status
Completed
 
Locations

Investigative Site

Netphen, Germany, 57250

Status
Completed
 
Locations

Investigative Site

Dortmund, Germany, 44328

Status
Completed
 
Locations

Investigative Site

Weinheim, Germany, 69469

Status
Completed
 
Locations

Investigative Site

Speyer, Germany, 67346

Status
Completed
 
Locations

Investigative Site

Hanau, Germany, 63450

Status
Completed
 
Locations

Investigative Site

Aachen, Germany, 52074

Status
Completed
 
Locations

Investigative Site

Marl, Germany, 45770

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 10407

Status
Completed
 
Locations

Investigative Site

Wetter, Germany, 58300

Status
Completed
 
Locations

Investigative Site

Langenfeld, Germany, 40764

Status
Completed
 
Locations

Investigative Site

Künzing, Germany, 94550

Status
Completed
 
Locations

Investigative Site

Aachen, Germany, 52080

Status
Completed
 
Locations

Investigative Site

Kelkheim, Germany, 65779

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 13057

Status
Completed
 
Locations

Investigative Site

Essen, Germany, 45355

Status
Completed
 
Locations

Investigative Site

Potsdam, Germany, 14778

Status
Completed
 
Locations

Investigative Site

Dortmund, Germany, 44139

Status
Completed
 
Locations

Investigative Site

Leipzig, Germany, 04249

Status
Completed
 
Locations

Investigative Site

Porta Westfalica, Germany, 32457

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 22143

Status
Completed
 
Locations

Investigative Site

Spalt, Germany, 91174

Status
Completed
 
Locations

Investigative Site

Welver, Germany, 59514

Status
Completed
 
Locations

Investigative Site

Stockach, Germany, 78333

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 10249

Status
Completed
 
Locations

Investigative Site

Dossenheim, Germany, 69221

Status
Completed
 
Locations

Investigative Site

Bergrheinfeld, Germany, 97493

Status
Completed
 
Locations

Investigative Site

Weyhe, Germany, 28844

Status
Completed
 
Locations

Investigative Site

Greven, Germany, 48268

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 22299

Status
Completed
 
Locations

Investigative Site

Bad Sassendorf, Germany, 59505

Status
Completed
 
Locations

Investigative Site

Hünxe, Germany, 46569

Status
Completed
 
Locations

Investigative Site

Reinfeld, Germany, 23858

Status
Completed
 
Locations

Investigative Site

Remscheid, Germany, 42897

Status
Completed
 
Locations

Investigative Site

Blankenhain, Germany, 99444

Status
Completed
 
Locations

Investigative Site

Bad Salzuflen, Germany, 32108

Status
Completed
 
Locations

Investigative Site

Sinzheim, Germany, 76547

Status
Completed
 
Locations

Investigative Site

Graben-Neudorf, Germany, 76676

Status
Completed
 
Locations

Investigative Site

Benningen, Germany, 71726

Status
Completed
 
Locations

Investigative Site

Heilbronn, Germany, 74080

Status
Completed
 
Locations

Investigative Site

Trossingen, Germany, 78647

Status
Completed
 
Locations

Investigative Site

Schwetzingen, Germany, 68723

Status
Completed
 
Locations

Investigative Site

Schrobenhausen, Germany, 86529

Status
Completed
 
Locations

Investigative Site

Ursensollen, Germany, 92289

Status
Completed
 
Locations

Investigative Site

Sulzbach-Rosenberg, Germany, 92237

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 13467

Status
Completed
 
Locations

Investigative Site

Ketzin, Germany, 14669

Status
Completed
 
Locations

Investigative Site

Horneburg, Germany, 21640

Status
Completed
 
Locations

Investigative Site

Bockenem, Germany, 31167

Status
Completed
 
Locations

Investigative Site

Beucha, Germany, 04824

Status
Completed
 
Locations

Investigative Site

Oberwiesenthal, Germany, 09484

Status
Completed
 
Locations

Investigative Site

Halle, Germany, 06124

Status
Completed
 
Locations

Investigative Site

Ludwigsburg, Germany, 71640

Status
Completed
 
Locations

Investigative Site

Gars, Germany, 83536

Status
Completed
 
Locations

Investigative Site

Strasskirchen, Germany, 94342

Status
Completed
 
Locations

Investigative Site

München, Germany, 80336

Status
Completed
 
Locations

Investigative Site

Cottbus, Germany, 03046

Status
Completed
 
Locations

Investigative Site

Rotenburg, Germany, 36199

Status
Completed
 
Locations

Investigative Site

Jühnde, Germany, 37127

Status
Completed
 
Locations

Investigative Site

Braunschweig, Germany, 38100

Status
Completed
 
Locations

Investigative Site

Essen, Germany, 45130

Status
Completed
 
Locations

Investigative Site

Essen, Germany, 45359

Status
Completed
 
Locations

Investigative Site

Ludwigshafen, Germany, 67063

Status
Completed
 
Locations

Investigative Site

Bochum, Germany, 44797

Status
Completed
 
Locations

Investigative Site

Dortmund, Germany, 44339

Status
Completed
 
Locations

Investigative Site

Freudenberg, Germany, 57258

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 13405

Status
Completed
 
Locations

Investigative Site

Frankfurt, Germany, 65929

Status
Completed
 
Locations

Investigative Site

Riesa, Germany, 01587

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01127

Status
Completed
 
Locations

Investigative Site

Rhaunen, Germany, 55624

Status
Completed
 
Locations

Investigative Site

Essen, Germany, 45276

Status
Completed
 
Locations

Investigative Site

Papenburg, Germany, 26871

Status
Completed
 
Locations

Investigative Site

Delitzsch, Germany, 04509

Status
Completed
 
Locations

Investigative Site

Mainz, Germany, 55116

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01069

Status
Completed
 
Locations

Investigative Site

Meißen, Germany, 01662

Status
Completed
 
Locations

Investigative Site

Grimma, Germany, 04668

Status
Completed
 
Locations

Investigative Site

Borna, Germany, 04552

Status
Completed
 
Locations

Investigative Site

Münster, Germany, 48167

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 13055

Status
Completed
 
Locations

Investigative Site

Mainz, Germany, 55127

Status
Completed
 
Locations

Investigative Site

Leipzig, Germany, 04103

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 22041

Status
Completed
 
Locations

Investigative Site

Hockenheim, Germany, 68766

Status
Completed
 
Locations

Investigative Site

Kallstadt, Germany, 67169

Status
Completed
 
Locations

Investigative Site

Oberaurach, Germany, 97514

Status
Completed
 
Locations

Investigative Site

Sand am Main, Germany, 97522

Status
Completed
 
Locations

Investigative Site

Loxstedt, Germany, 27612

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 12099

Status
Completed
 
Locations

Investigative Site

Stuttgart, Germany, 70378

Status
Completed
 
Locations

Investigative Site

Siegen, Germany, 57072

Status
Completed
 
Locations

Investigative Site

Witten, Germany, 58455

Status
Completed
 
Locations

Investigative Site

Markkleeberg, Germany, 04416

Status
Completed
 
Locations

Investigative Site

Kamp-Lintfort, Germany, 47475

Status
Completed
 
Locations

Investigative Site

High Valleyfield, United Kingdom, KY12 8SJ

Status
Completed
 
Locations

Investigative Site

Saltash, United Kingdom, PL12 6DL

Status
Completed
 
Locations

Investigative Site

Barry, United Kingdom, CF63 4HP

Status
Completed
 
Locations

Investigative Site

Penzance, United Kingdom, TR19 7HX

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 22335

Status
Completed
 
Locations

Investigative Site

Dinkelsbühl, Germany, 91550

Status
Completed
 
Locations

Investigative Site

Elsterwerda, Germany, 04910

Status
Completed
 
Locations

Investigative Site

Wermsdorf, Germany, 04779

Status
Completed
 
Locations

Investigative Site

Dresden, Germany, 01277

Status
Completed
 
Locations

Investigative Site

Berlin, Germany, 14050

Status
Completed
 
Locations

Investigative Site

Duisburg, Germany, 47199

Status
Completed
 
Locations

Investigative Site

Krefeld, Germany, 47798

Status
Completed
 
Locations

Investigative Site

Bitterfeld, Germany, 06749

Status
Completed
 
Locations

Investigative Site

Hamburg, Germany, 22177

Status
Completed
 
Locations

Investigative Site

Hohenau, Germany, 94545

Status
Completed
 
Locations

Investigative Site

Boscastle, United Kingdom, PL35 0BG

Status
Completed
 
Locations

Investigative Site

Ely, United Kingdom, CB7 5SQ

Status
Completed
 
Locations

Investigative Site

Sheffield, United Kingdom, S7 2DW

Status
Completed
 
Locations

Investigative Site

Motherwell, United Kingdom, ML1 3JX

Status
Completed
 
Locations

Investigative Site

St Austell, United Kingdom, PL26 7RL

Status
Completed
 
Locations

Investigative Site

Ely, United Kingdom, CB7 4HF

Status
Completed
 
Locations

Investigative Site

Slough, United Kingdom, SL1 1TT

Status
Completed
 
Locations

Investigative Site

Cardiff, United Kingdom, CF5 4AD

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS25 1AN

Status
Completed
 
Locations

Investigative Site

Peterborough, United Kingdom, PE7 3JL

Status
Completed
 
Locations

Investigative Site

Hamilton, United Kingdom, ML3 ODR

Status
Completed
 
Locations

Investigative Site

Darlington, United Kingdom, DL2 1AA

Status
Completed
 
Locations

Investigative Site

Thedinghausen, Germany, 27321

Status
Completed
 
Locations

Investigative Site

Nienburg, Germany, 31582

Status
Completed
 
Locations

Investigative Site

Ettlingen, Germany, 78275

Status
Completed
 
Locations

Investigative Site

Northeim, Germany, 37154

Status
Completed
 
Locations

Investigative Site

Aurich, Germany, 26603

Status
Completed
 
Locations

Investigative Site

Rehburg-Loccum, Germany, 31547

Status
Completed
 
Locations

Investigative Site

Daaden, Germany, 57567

Status
Completed
 
Locations

Investigative Site

Riede, Germany, 27339

Status
Completed
 
Locations

Investigative Site

Chipping Norton, United Kingdom, OX75FA

Status
Completed
 
Locations

Investigative Site

Bath, United Kingdom, BA11 2FH

Status
Completed
 
Locations

Investigative Site

Crawley, United Kingdom, RH10 7DX

Status
Completed
 
Locations

Investigative Site

Letchworth, United Kingdom, SG6 4TS

Status
Completed
 
Locations

Investigative Site

Wells-Next-The-Sea, United Kingdom, NR23 1JP

Status
Completed
 
Locations

Investigative Site

Wishaw, United Kingdom, ML2 7BQ

Status
Completed
 
Locations

Investigative Site

Sandbach, United Kingdom, CW11 1EQ

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS25 7AB

Status
Completed
 
Locations

Investigative Site

Peterborough, United Kingdom, PE8 6PL

Status
Completed
 
Locations

Investigative Site

Wymondham, United Kingdom, NR18 0RF

Status
Completed
 
Locations

Investigative Site

Bath, United Kingdom, BA2 4BY

Status
Completed
 
Locations

Investigative Site

Penzance, United Kingdom, TR18 4EL

Status
Completed
 
Locations

Investigative Site

Wellingborough, United Kingdom, NN8 4RW

Status
Completed
 
Locations

Investigative Site

Plymouth, United Kingdom, PL6 7TH

Status
Completed
 
Locations

Investigative Site

Bradford-on-Avon, United Kingdom, BA15 1DQ

Status
Completed
 
Locations

Investigative Site

Fowey, United Kingdom, PL23 1DT

Status
Completed
 
Locations

Investigative Site

Penzance, United Kingdom, TR18 4JH

Status
Completed
 
Locations

Investigative Site

Chippenham, United Kingdom, SN14 6GT

Status
Completed
 
Locations

Investigative Site

Bath, United Kingdom, BA2 4JT

Status
Completed
 
Locations

Investigative Site

Crawley, United Kingdom, RH10 1LL

Status
Completed
 
Locations

Investigative Site

Bath, United Kingdom, BA2 3HT

Status
Completed
 
Locations

Investigative Site

Chippenham, United Kingdom, SN15 2SB

Status
Completed
 
Locations

Investigative Site

Westbury, United Kingdom, BA13 3FQ

Status
Completed
 
Locations

Investigative Site

Annan, United Kingdom, DG12 6BG

Status
Completed
 
Locations

Investigative Site

New Stevenson, United Kingdom, ML1 4LT

Status
Completed
 
Locations

Investigative Site

Darlington, United Kingdom, DL3 7JR

Status
Completed
 
Locations

Investigative Site

Bangor, United Kingdom, BT19 1PP

Status
Completed
 
Locations

Investigative Site

Antrim, United Kingdom, BT36 4PP

Status
Completed
 
Locations

Investigative Site

Antrim, United Kingdom, BT37 9QN

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G21 1TR

Status
Completed
 
Locations

Investigative Site

Aberdeen, United Kingdom, AB25 2ZD

Status
Completed
 
Locations

Investigative Site

Chestfield, United Kingdom, CT5 3QU

Status
Completed
 
Locations

Investigative Site

Canterbury, United Kingdom, CT1 3HX

Status
Completed
 
Locations

Investigative Site

Chesterfield, United Kingdom, S40 4AA

Status
Completed
 
Locations

Investigative Site

Eccles, United Kingdom, S35 9XQ

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G67 1BJ

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G45 9AW

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G20 0XA

Status
Completed
 
Locations

Investigative Site

London, United Kingdom, SW12 8EU

Status
Completed
 
Locations

Investigative Site

Trowbridge, United Kingdom, BA14 9AR

Status
Completed
 
Locations

Investigative Site

Doncaster, United Kingdom, DN1 2ET

Status
Completed
 
Locations

Investigative Site

Coventry, United Kingdom, CV7 8LA

Status
Completed
 
Locations

Investigative Site

Blantyre, United Kingdom, G72 0BS

Status
Completed
 
Locations

Investigative Site

Leigh-on-Sea, United Kingdom, SS9 2SQ

Status
Completed
 
Locations

Investigative Site

Hamilton, United Kingdom, ML3 8AA

Status
Completed
 
Locations

Investigative Site

Coatbridge, United Kingdom, ML5 3AP

Status
Completed
 
Locations

Investigative Site

Chapelhall, United Kingdom, ML6 8SR

Status
Completed
 
Locations

Investigative Site

Worcester Park, United Kingdom, KT4 7BX

Status
Completed
 
Locations

Investigative Site

Hinckley, United Kingdom, LE10 2SE

Status
Completed
 
Locations

Investigative Site

Hitchin, United Kingdom, SG4 9TH

Status
Completed
 
Locations

Investigative Site

East Horsley, United Kingdom, KT24 6QT

Status
Completed
 
Locations

Investigative Site

Blackpool, United Kingdom, FY3 7EN

Status
Completed
 
Locations

Investigative Site

Antrim, United Kingdom, BT38 9TG

Status
Completed
 
Locations

Investigative Site

Hamilton, United Kingdom, ML3 7EN

Status
Completed
 
Locations

Investigative Site

Addlestone, United Kingdom, KT15 2BH

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT12 5LT

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT12 5EY

Status
Completed
 
Locations

Investigative Site

Coventry, United Kingdom, CV9 1EU

Status
Completed
 
Locations

Investigative Site

Radstock, United Kingdom, BA3 2UH

Status
Completed
 
Locations

Investigative Site

Luton, United Kingdom, LU2 9SB

Status
Completed
 
Locations

Investigative Site

Bury St. Edmunds, United Kingdom, IP32 7EW

Status
Completed
 
Locations

Investigative Site

Bolton, United Kingdom, BL3 6TL

Status
Completed
 
Locations

Investigative Site

Dronfield, United Kingdom, S18 8QY

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS26 8SZ

Status
Completed
 
Locations

Investigative Site

Bishop Auckland, United Kingdom, DL14 6AB

Status
Completed
 
Locations

Investigative Site

Stowmarket, United Kingdom, IP14 1NL

Status
Completed
 
Locations

Investigative Site

Inverness, United Kingdom, IV2 4AG

Status
Completed
 
Locations

Investigative Site

Irvine, United Kingdom, KA12 0AY

Status
Completed
 
Locations

Investigative Site

Blackpool, United Kingdom, FY4 3AD

Status
Completed
 
Locations

Investigative Site

Peterborough, United Kingdom, PE2 5GP

Status
Completed
 
Locations

Investigative Site

Antrim, United Kingdom, BT41 3AE

Status
Completed
 
Locations

Investigative Site

Tyrone, United Kingdom, BT80 8BG

Status
Completed
 
Locations

Investigative Site

Darlington, United Kingdom, DL3 8SQ

Status
Completed
 
Locations

Investigative Site

Whitstable, United Kingdom, CT5 3SE

Status
Completed
 
Locations

Investigative Site

Rugby, United Kingdom, CV21 3SP

Status
Completed
 
Locations

Investigative Site

Doncaster, United Kingdom, DN1 2EU

Status
Completed
 
Locations

Investigative Site

Ipswich, United Kingdom, IP4 2PU

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS10 3NB

Status
Completed
 
Locations

Investigative Site

Newcastle Upon Tyne, United Kingdom, NE15 6TQ

Status
Completed
 
Locations

Investigative Site

Coatrbridge, United Kingdom, ML5 3BJ

Status
Completed
 
Locations

Investigative Site

Carstairs, United Kingdom, ML11 8QD

Status
Completed
 
Locations

Investigative Site

Thornhill, United Kingdom, DG3 5AA

Status
Completed
 
Locations

Investigative Site

Bolton, United Kingdom, BL5 3UB

Status
Completed
 
Locations

Investigative Site

Witley Bay, United Kingdom, NE26 1NA

Status
Completed
 
Locations

Investigative Site

Craigavon, United Kingdom, BT67 0LQ

Status
Completed
 
Locations

Investigative Site

Newtonabbey, United Kingdom, BT37 9QU

Status
Completed
 
Locations

Investigative Site

Belvidere, United States, 07823

Status
Completed
 
Locations

Investigative Site

Taylors, United States, 29687

Status
Completed
 
Locations

Investigative Site

Atlanta, United States, 30318

Status
Completed
 
Locations

Investigative Site

Bury St Edmonds, United Kingdom, IP30 9QU

Status
Completed
 
Locations

Investigative Site

Tiptree, United Kingdom, CO5 0HB

Status
Completed
 
Locations

Investigative Site

Bellshill, United Kingdom, ML4 1PS

Status
Completed
 
Locations

Investigative Site

Brighton, United Kingdom, BN2 1ES

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G5 0BQ

Status
Completed
 
Locations

Investigative Site

Johnstone, United Kingdom, PA5 8EY

Status
Completed
 
Locations

Investigative Site

Airedire, United Kingdom, ML66DB

Status
Completed
 
Locations

Investigative Site

Paisley, United Kingdom

Status
Completed
 
Locations

Investigative Site

Letchworth, United Kingdom, SG6 4UB

Status
Completed
 
Locations

Investigative Site

Corsham, United Kingdom, SN3 9DL

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT5 7BP

Status
Completed
 
Locations

Investigative Site

Glasgow, United Kingdom, G52 3QN

Status
Completed
 
Locations

Investigative Site

Coventry, United Kingdom, CV6 4DD

Status
Completed
 
Locations

Investigative Site

Manchester, United Kingdom, M13 9WL

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT13 3BW

Status
Completed
 
Locations

Tallahassee Memorial Family

Quincy, United States, 32351

Status
Completed
 
Locations

Investigative Site

Marianna, United States, 32446-2120

Status
Completed
 
Locations

Investigative Site

Tucson, United States, 85712

Status
Completed
 
Locations

Investigative Site

Daingerfield, United States, 75638

Status
Completed
 
Locations

Investigative Site

Carlisle, United States, 45005-3320

Status
Completed
 
Locations

Investigative Site

Clifton, United States, 07013

Status
Completed
 
Locations

Investigative Site

Huntington Park, United States, 90255

Status
Completed
 
Locations

Medical Research Centers of South Florida, Inc.

Hollywood, United States, 33021

Status
Completed
 
Locations

Investigative Site

Broken Bow, United States, 68822

Status
Completed
 
Locations

Investigative Site

Carryduff, United Kingdom, BT8 8HR

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT1 2JR

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT15 2GE

Status
Completed
 
Locations

Investigative Site

Ballymena, United Kingdom, BT43 6JD

Status
Completed
 
Locations

Investigative Site

Ballymena, United Kingdom, BT42 4JP

Status
Completed
 
Locations

Investigative Site

Crumlin, United Kingdom, BT29 4LP

Status
Completed
 
Locations

Investigative Site

Watford, United Kingdom, WD25 7NL

Status
Completed
 
Locations

Investigative Site

Bath, United Kingdom, BA1 2SR

Status
Completed
 
Locations

Investigative Site

Dundee, United Kingdom, DD19SY

Status
Completed
 
Locations

Investigative Site

Hadleigh, United Kingdom, IP7 5DN

Status
Completed
 
Locations

Investigative Site

Bury St. Edmunds, United Kingdom, IP31 2HD

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS15 9JH

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS25 1HB

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS118BS

Status
Completed
 
Locations

Investigative Site

Vernon Hills, United States, 60061

Status
Completed
 
Locations

Investigative Site

San Marcos, United States, 78666

Status
Completed
 
Locations

Investigative Site

Montgomery, United States, 45242

Status
Completed
 
Locations

Office of Dr.Larry Levinson, DO

Hollywood, United States, 33021

Status
Completed
 
Locations

Investigative Site

Jersey City, United States, 07306

Status
Completed
 
Locations

Investigative Site

Greensboro, United States, 27401

Status
Completed
 
Locations

Investigative Site

Scottsdale, United States, 85260

Status
Completed
 
Locations

Investigative Site

Rancho Cucamonga, United States, 91730

Status
Completed
 
Locations

Investigative Site

Rolling Hills Estates, United States, 90274

Status
Completed
 
Locations

Medical Research Trust

Boynton Beach, United States, 33426

Status
Completed
 
Locations

Investigative Site

Birmingham, United States, 39294

Status
Completed
 
Locations

Investigative Site

Stratford, United States, 08084

Status
Completed
 
Locations

Investigative Site

Leeds, United Kingdom, LS9 9EF

Status
Completed
 
Locations

Investigative Site

Forth, United Kingdom, ML1 8AJ

Status
Completed
 
Locations

Investigative Site

Lockerbie, United Kingdom, D11 2BJ

Status
Completed
 
Locations

Investigative Site

Crossgar, United Kingdom, BT30 9JU

Status
Completed
 
Locations

Investigative Site

Belfast, United Kingdom, BT8 6GR

Status
Completed
 
Locations

Investigative Site

Kissimmee, United States, 34741

Status
Completed
 
Locations

Investigative Site

Port Gibson, United States, 39150

Status
Completed
 
Locations

Investigative Site

Prince Frederick, United States, 20678

Status
Completed
 
Locations

Investigative Site

Sugar Land, United States, 77478

Status
Completed
 
Locations

Investigative Site

Gainesville, United States, 32601

Status
Completed
 
Locations

Investigative Site

Hialeah, United States, 33016

Status
Completed
 
Locations

Investigative Site

Tampa, United States, 33614

Status
Completed
 
Locations

Investigative Site

Lockport, United States, 60491

Status
Completed
 
Locations

Investigative Site

Evansville, United States, 47713

Status
Completed
 
Locations

Investigative Site

Lebanon, United States, 40033

Status
Completed
 
Locations

Merit Medical Group, Inc.

Richlands, United States, 24641-2067

Status
Completed
 
Locations

Investigative Site

Phoenix, United States, 85051

Status
Completed
 
Locations

Investigative Site

Duncansville, United States, 16635

Status
Completed
 
Locations

Investigative Site

Omaha, United States, 68116-2004

Status
Completed
 
Locations

Helping Hands Clinical Trials

Santa Ana, United States, 92704

Status
Completed
 
Locations

Investigative Site

Lawrenceville, United States, 08648

Status
Completed
 
Locations

Investigative Site

Graysville, United States, 35073

Status
Completed
 
Locations

Investigative Site

Hot Springs, United States, 71913-4457

Status
Completed
 
Locations

Investigative Site

Rockwall, United States, 75032

Status
Completed
 
Locations

Investigative Site

Perrysburg, United States, 43551

Status
Completed
 
Locations

Investigative Site

Marion, United States, 43302

Status
Completed
 
Locations

Investigative Site

Raleigh, United States, 27609

Status
Completed
 
Locations

Investigative Site

Los Angeles, United States, 90025

Status
Completed
 
Locations

Investigative Site

Pell City, United States, 35125

Status
Completed
 
Locations

Investigative Site

Largo, United States, 33770

Status
Completed
 
Locations

Investigative Site

Chicago, United States, 60628

Status
Completed
 
Locations

Investigative Site

Chicago, United States, 60631-1958

Status
Completed
 
Locations

Investigative Site

Newark, United States, 19702

Status
Completed
 
Locations

Investigative Site

Doylestown, United States, 18901

Status
Completed
 
Locations

Investigative Site

San Antonio, United States, 78205-1116

Status
Completed
 
Locations

Investigative Site

Fort Wayne, United States, 46804

Status
Completed
 
Locations

Investigative Site

Bridgman, United States, 49106

Status
Completed
 
Locations

Investigative Site

Interlochen, United States, 49643-9264

Status
Completed
 
Locations

Investigative Site

Cadillac, United States, 49601

Status
Completed
 
Locations

Investigative Site

Florissant, United States, 63031

Status
Completed
 
Locations

Investigative Site

Stephenville, United States, 76401

Status
Completed
 
Locations

Investigative Site

Honaker, United States, 24260

Status
Completed
 
Locations

Investigative Site

Burlington, United States, 27215

Status
Completed
 
Locations

Investigative Site

Cherry Hill, United States, 08084

Status
Completed
 
Locations

Investigative Site

Manati, United States, 00674

Status
Completed
 
Locations

Investigative Site

Guaynabo, United States, 00968

Status
Completed
 
Locations

Investigative Site

Trujilo Alto, United States, 00976

Status
Completed
 
Locations

Investigative Site

Skierniewice, Poland, 96-100

Status
Completed
 
Locations

Investigative Site

Poznan, Poland, 60-539

Status
Completed
 
Locations

Investigative Site

Sobotka, Poland

Status
Completed
 
Locations

Investigative Site

Lublin, Poland, 20-258

Status
Completed
 
Locations

Investigative Site

Lodz, Poland

Status
Completed
 
Locations

Investigative Site

Chrzanow, Poland

Status
Completed
 
Locations

Investigative Site

Wloclawek, Poland

Status
Completed
 
Locations

Investigative Site

Linia, Poland, 84-223

Status
Completed
 
Locations

Investigative Site

Katowice, Poland, 40-752

Status
Completed
 
Locations

Investigative Site

Lublin, Poland

Status
Completed
 
Locations

Investigative Site

Linden, United States, 07036

Status
Completed
 
Locations

PharmaTrials, Inc.

Perth Amboy, United States, 08861

Status
Completed
 
Locations

Investigative Site

McKinney, United States, 75069

Status
Completed
 
Locations

Investigative Site

Panama City, United States, 32401

Status
Completed
 
Locations

Investigative Site

Columbus, United States, 28722

Status
Completed
 
Locations

Investigative Site

Troy, United States, 48085

Status
Completed
 
Locations

Investigative Site

Krakow, Poland, 31-567

Status
Completed
 
Locations

Investigative Site

Radom, Poland, 26-600

Status
Completed
 
Locations

Investigative Site

Lancut, Poland

Status
Completed
 
Locations

Investigative Site

Olkusz, Poland

Status
Completed
 
Locations

Investigative Site

Gdansk, Poland, 80-286

Status
Completed
 
Locations

Investigative Site

Skierniewice, Poland

Status
Completed
 
Locations

Investigative Site

Katowice, Poland, 40-226

Status
Completed
 
Locations

Investigative Site

Gliwice, Poland, 44-109

Status
Completed
 
Locations

Investigative Site

Bialystok, Poland, 15-183

Status
Completed
 
Locations

Investigative Site

Krakow, Poland, 31-637

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 02-796

Status
Completed
 
Locations

Investigative Site

Wroclaw, Poland, 51-112

Status
Completed
 
Locations

Investigative Site

Gdynia, Poland, 81-317

Status
Completed
 
Locations

Investigative Site

Sellersville, United States, 18960

Status
Completed
 
Locations

Investigative Site

Omaha, United States, 68114

Status
Completed
 
Locations

Investigative Site

Fremont, United States, 94536-3702

Status
Completed
 
Locations

Investigative Site

Hainesport, United States, 08036

Status
Completed
 
Locations

Investigative Site

Krakow, Poland, 31-156

Status
Completed
 
Locations

Investigative Site

Varese, Italy, 21100

Status
Completed
 
Locations

Investigative Site

Grosseto, Italy, 58100

Status
Completed
 
Locations

Investigative Site

Torino, Italy, 10023

Status
Completed
 
Locations

Investigative Site

Bergamo, Italy, 24128

Status
Completed
 
Locations

Investigative Site

Orocovis, United States, 00720

Status
Completed
 
Locations

Investigative Site

San Juan, United States, 00918

Status
Completed
 
Locations

Investigative Site

San Juan, United States, 00918

Status
Terminated
 
Locations

Investigative Site

Sopot, Poland, 81-746

Status
Completed
 
Locations

Investigative Site

Wola, Poland

Status
Completed
 
Locations

Investigative Site

Czechowice-Dziedzice, Poland

Status
Completed
 
Locations

Investigative Site

Lublin, Poland, 20-044

Status
Completed
 
Locations

Investigative Site

Malaszewicze, Poland

Status
Completed
 
Locations

Investigative Site

Bydgoszcz, Poland, 85-863

Status
Completed
 
Locations

Investigative Site

Naklo nad Notecia, Poland, 98-100

Status
Completed
 
Locations

Investigative Site

Grodzisk Mazowiecki, Poland, 05-825

Status
Completed
 
Locations

Investigative Site

Amandola, Italy, 63021

Status
Completed
 
Locations

Investigative Site

Chiavari, Italy, 16043

Status
Completed
 
Locations

Investigative Site

Catania, Italy, 95124

Status
Completed
 
Locations

Investigative Site

Roma, Italy, 00161

Status
Completed
 
Locations

Investigative Site

Roma, Italy, 00157

Status
Completed
 
Locations

Investigative Site

Legnano, Italy, 20025

Status
Completed
 
Locations

Investigative Site

Chieti, Italy, 66100

Status
Completed
 
Locations

Investigative Site

Asti, Italy, 14100

Status
Completed
 
Locations

Investigative Site

Krakow, Poland

Status
Completed
 
Locations

Investigative Site

Wejherowo, Poland

Status
Completed
 
Locations

Investigative Site

Szczyrk, Poland, 43-370

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 02-507

Status
Completed
 
Locations

Investigative Site

Bydgoszcz, Poland

Status
Completed
 
Locations

Investigative Site

Elblag, Poland, 82-300

Status
Completed
 
Locations

Investigative Site

Przeworsk, Poland, 37-200

Status
Completed
 
Locations

Investigative Site

Kutno, Poland, 99-300

Status
Completed
 
Locations

Investigative Site

Ostrow Wielkopolski, Poland, 63-400

Status
Completed
 
Locations

Investigative Site

Zabrze, Poland

Status
Completed
 
Locations

Investigative Site

Krakow, Poland, 31-011

Status
Completed
 
Locations

Investigative Site

Wabrzezno, Poland

Status
Completed
 
Locations

Investigative Site

Barcelona, Spain, 08023

Status
Completed
 
Locations

Investigative Site

Barcelona, Spain, 08025

Status
Completed
 
Locations

Investigative Site

Murcia, Spain, 30008

Status
Completed
 
Locations

Investigative Site

Vic (Barcelona), Spain, 08500

Status
Completed
 
Locations

Investigative Site

Murcia, Spain, 30007

Status
Completed
 
Locations

Investigative Site

Petrer, Spain, 03610

Status
Completed
 
Locations

Investigative Site

Oviedo, Spain, 33013

Status
Completed
 
Locations

Investigative Site

Posada de Llanes, Spain, 33594

Status
Completed
 
Locations

Investigative Site

Madrid, Spain, 28003

Status
Completed
 
Locations

Investigative Site

León, Spain, 24001

Status
Completed
 
Locations

Investigative Site

Krakow, Poland, 30-424

Status
Completed
 
Locations

Investigative Site

Warszawa, Poland, 01-192

Status
Completed
 
Locations

Investigative Site

Gdansk, Poland, 80-822

Status
Completed
 
Locations

Investigative Site

Gdansk, Poland, 80-461

Status
Completed
 
Locations

Investigative Site

Wroclaw, Poland, 50-127

Status
Completed
 
Locations

Investigative Site

Malbork, Poland, 82-200

Status
Completed
 
Locations

Investigative Site

Oviedo, Spain, 33009

Status
Completed
 
Locations

Investigative Site

Lugo, Spain, 27770

Status
Completed
 
Locations

Investigative Site

León, Spain

Status
Completed
 
Locations

Investigative Site

Viveiro, Spain, 27850

Status
Completed
 
Locations

Investigative Site

Madrid, Spain, 28032

Status
Completed
 
Locations

Investigative Site

Orense, Spain, 32003

Status
Completed
 
Locations

Investigative Site

Elche, Spain

Status
Completed
 
Locations

Investigative Site

Novara, Italy, 28100

Status
Completed
 
Locations

Investigative Site

Reggio Emilia, Italy, 42019

Status
Completed
 
Locations

Investigative Site

Foggia, Italy, 71100

Status
Completed
 
Locations

Investigative Site

Chieri, Italy, 10023

Status
Completed
 
Locations

Investigative Site

Reggio Emilia, Italy, 42123

Status
Completed
 
Locations

Investigative Site

Moncalieri, Italy, 10024

Status
Completed
 
Locations

Investigative Site

Como, Italy, 22066

Status
Completed
 
Locations

Investigative Site

Napoli, Italy, 80131

Status
Completed
 
Locations

Investigative Site

Badajoz, Spain, 06140

Status
Completed
 
Locations

Investigative Site

La Victoria, Spain, 38380

Status
Completed
 
Locations

Investigative Site

Gümar, Spain, 38591

Status
Completed
 
Locations

Investigative Site

Benidorm, Spain, 03503

Status
Completed
 
Locations

Investigative Site

Enniscorthy, Ireland

Status
Completed
 
Locations

Investigative Site

Cork, Ireland

Status
Completed
 
Locations

Investigative Site

Alcover, Spain, 43460

Status
Completed
 
Locations

Investigative Site

Begonte, Spain, 27373

Status
Completed
 
Locations

Investigative Site

Murcia, Spain, 300005

Status
Completed
 
Locations

Investigative Site

Kilmallock, Ireland

Status
Completed
 
Locations

Investigative Site

Tallow, Ireland

Status
Completed
 
Locations

Investigative Site

Dublin, Ireland, 2

Status
Completed
 
Locations

Investigative Site

Espinardo, Spain, 30100

Status
Completed
 
Locations

Investigative Site

Xixona, Spain, 03100

Status
Completed
 
Locations

Investigative Site

Alicante, Spain, 03007

Status
Completed
 
Locations

Investigative Site

Albacete, Spain, 2260

Status
Completed
 
Locations

Investigative Site

Huelva, Spain, 21003

Status
Completed
 
Locations

Investigative Site

Barcelona, Spain, 08017

Status
Completed
 
Locations

Investigative Site

Salamanca, Spain, 27-31

Status
Completed
 
Locations

Investigative Site

Sobrado dos Monxes, Spain, 15813

Status
Completed
 
Locations

Investigative Site

Valladolid, Spain, 47007

Status
Completed
 
Locations

Investigative Site

Santander, Spain, 39009

Status
Completed
 
Locations

Investigative Site

Madrid, Spain, 28030

Status
Completed
 
Locations

Investigative Site

La Roda, Spain, 06230

Status
Completed
 
Locations

Investigative Site

Gorey, Ireland

Status
Completed
 
Locations

Investigative Site

Bray, Ireland

Status
Completed
 
Locations

Investigative Site

Rathkeale, Ireland

Status
Completed
 
Locations

Investigative Site

Bishopstown, Ireland

Status
Completed
 

Trial Design