Trial Condition(s):
Moderate Risk of CVD
A Study to Assess the Efficacy and Safety of Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease (ARRIVE)
Bayer Identifier:
12198
ClinicalTrials.gov Identifier:
EudraCT Number:
EU CT Number:
Not Available
Trial Purpose
The use of acetylsalicylic acid in the primary prevention of cardiovascular events has been extensively studied but to a lesser extent in patients with moderate levels of cardiovascular risk. The current study is designed to prove the efficacy and tolerability of 100 mg enteric-coated Aspirin versus placebo in the prevention of cardiovascular disease (CVD) events, which include fatal and nonfatal myocardial infarction, fatal and nonfatal stroke and CV death, in a population with no history of known CVD who are at moderate risk of major CHD events (approximately 10-20% 10 year CHD risk). This corresponds to a patient population mean 10-year CVD risk of approximately 30%. Subjects are treated in a standard care setting and may receive treatment for the underlying risk factors as defined by the treating physician. Outcome events will be adjudicated by an Endpoint Adjudication Committee and the study will be monitored by an independent Data Safety Monitoring Board.
Inclusion Criteria
- Males aged 55 years and above with 2 to 4 risk factors. Male Risk Factors: -- Elevated cholesterol (Tchol>200 mg/dL or LDL>130 mg/dL; as measured at screening) irrespective of current treatment -- Current smoking: defined as any cigarette smoking in the past 12 months -- Low HDL cholesterol (HDL<40 mg/dL; as measured at screening) -- Elevated blood pressure (SBP>140 mmHg; as measured at screening) -- Currently on any medication to treat high blood pressure -- Positive family history of early CHD (a first-degree relative [father, mother, brother, sister, son, daughter] suffered a heart attack [myocardial infarction] before the age of 60 years) - Females aged 60 and above with 3 or more risk factors. Female Risk Factors: -- Elevated cholesterol (Tchol>240 mg/dL or LDL>160 mg/dL; as measured at screening) irrespective of current treatment -- Current smoking: defined as any cigarette smoking in the past 12 months -- Low HDL cholesterol (HDL<40 mg/dL; as measured at screening) -- Elevated blood pressure (SBP>140 mmHg; as measured at screening) -- Currently on any medication to treat high blood pressure -- Positive family history of early CHD (a first-degree relative [father, mother, brother, sister, son, daughter] suffered a heart attack [myocardial infarction] before the age of 60 years) - An understanding and willingness to comply with trial procedures and has given written informed consent to participate in the trial
Exclusion Criteria
- History of a documented vascular event, such as MI, stroke, coronary artery angioplasty or stenting, coronary artery bypass graft, relevant arrhythmias, or congestive heart failure or vascular intervention - Patients who are at higher than moderate risk on the basis of their diabetes status, other factors known to the investigator, or the currently used national risk score - Known contraindications to the study drug, e.g. hypersensitivity to acetylsalicylic acid - Recent (in the past year) history of gastrointestinal or genitourinary bleeding or other bleeding disorders - Active diagnosed and documented reflux esophagitis - Patients presenting with any medical condition, or psychiatric or substance abuse disorder, that, in the opinion of the investigator, is likely to affect the patient's ability to complete the study or precludes the patient's participation in the study - Lactating women or women of childbearing potential - Severe liver disease or damage based on the clinical judgment of the investigator - Severe renal disease or damage based on the clinical judgement of the investigator - A definite indication for acetylsalicylic acid therapy, other antiplatelet drug, or anticoagulant in the opinion of the physician - A history of asthma induced by administration of salicylates or substances with a similar action, notably NSAIDS - Chronic, frequent (> 5 days/month) use of NSAIDs (including aspirin, or aspirin containing products), COX-2 inhibitors or metamizole - Current participation in any other trials involving investigational products within 30 days prior to the Screening Visit - Current use of an anticoagulant medication - Sitting systolic blood pressure greater than 170 mmHg
Trial Summary
Enrollment Goal
Trial Dates
Phase
Could I receive a placebo?
Products
Accepts Healthy Volunteers
Where to Participate
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Locations Investigative Site Arnsberg, Germany, 59757 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Apolda, Germany, 99510 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Magdeburg, Germany, 39104 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bergkamen, Germany, 59192 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bad Lippspringe, Germany, 33175 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Nassau, Germany, 56377 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Winsen, Germany, 21423 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Deggingen, Germany, 73326 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Köln, Germany, 51069 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gransee, Germany, 16775 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Viersen, Germany, 41751 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wetter, Germany, 35083 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lienen, Germany, 49536 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bad Salzuflen, Germany, 32105 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stuhr, Germany, 28816 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Arzberg, Germany, 95659 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Frankfurt, Germany, 60599 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bad Bramstedt, Germany, 24576 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Löhne, Germany, 32584 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamm, Germany, 59069 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Essen, Germany, 45136 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wardenburg, Germany, 26203 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lippetal, Germany, 59510 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Netphen, Germany, 57250 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dortmund, Germany, 44328 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Weinheim, Germany, 69469 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Speyer, Germany, 67346 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hanau, Germany, 63450 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Aachen, Germany, 52074 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Marl, Germany, 45770 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 10407 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wetter, Germany, 58300 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Langenfeld, Germany, 40764 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Künzing, Germany, 94550 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Aachen, Germany, 52080 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kelkheim, Germany, 65779 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 13057 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Essen, Germany, 45355 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Potsdam, Germany, 14778 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dortmund, Germany, 44139 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leipzig, Germany, 04249 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Porta Westfalica, Germany, 32457 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamburg, Germany, 22143 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Spalt, Germany, 91174 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Welver, Germany, 59514 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stockach, Germany, 78333 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 10249 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dossenheim, Germany, 69221 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bergrheinfeld, Germany, 97493 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Weyhe, Germany, 28844 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Greven, Germany, 48268 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamburg, Germany, 22299 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bad Sassendorf, Germany, 59505 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hünxe, Germany, 46569 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Reinfeld, Germany, 23858 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Remscheid, Germany, 42897 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Blankenhain, Germany, 99444 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bad Salzuflen, Germany, 32108 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sinzheim, Germany, 76547 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Graben-Neudorf, Germany, 76676 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Benningen, Germany, 71726 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Heilbronn, Germany, 74080 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Trossingen, Germany, 78647 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Schwetzingen, Germany, 68723 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Schrobenhausen, Germany, 86529 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ursensollen, Germany, 92289 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sulzbach-Rosenberg, Germany, 92237 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 13467 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ketzin, Germany, 14669 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Horneburg, Germany, 21640 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bockenem, Germany, 31167 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Beucha, Germany, 04824 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Oberwiesenthal, Germany, 09484 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Halle, Germany, 06124 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ludwigsburg, Germany, 71640 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gars, Germany, 83536 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Strasskirchen, Germany, 94342 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site München, Germany, 80336 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Cottbus, Germany, 03046 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rotenburg, Germany, 36199 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Jühnde, Germany, 37127 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Braunschweig, Germany, 38100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Essen, Germany, 45130 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Essen, Germany, 45359 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ludwigshafen, Germany, 67063 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bochum, Germany, 44797 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dortmund, Germany, 44339 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Freudenberg, Germany, 57258 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 13405 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Frankfurt, Germany, 65929 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Riesa, Germany, 01587 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dresden, Germany, 01127 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rhaunen, Germany, 55624 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Essen, Germany, 45276 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Papenburg, Germany, 26871 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Delitzsch, Germany, 04509 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Mainz, Germany, 55116 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dresden, Germany, 01069 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Meißen, Germany, 01662 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Grimma, Germany, 04668 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Borna, Germany, 04552 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Münster, Germany, 48167 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 13055 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Mainz, Germany, 55127 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leipzig, Germany, 04103 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamburg, Germany, 22041 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hockenheim, Germany, 68766 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kallstadt, Germany, 67169 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Oberaurach, Germany, 97514 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sand am Main, Germany, 97522 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Loxstedt, Germany, 27612 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 12099 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stuttgart, Germany, 70378 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Siegen, Germany, 57072 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Witten, Germany, 58455 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Markkleeberg, Germany, 04416 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kamp-Lintfort, Germany, 47475 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site High Valleyfield, United Kingdom, KY12 8SJ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Saltash, United Kingdom, PL12 6DL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Barry, United Kingdom, CF63 4HP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Penzance, United Kingdom, TR19 7HX | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamburg, Germany, 22335 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dinkelsbühl, Germany, 91550 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Elsterwerda, Germany, 04910 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wermsdorf, Germany, 04779 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dresden, Germany, 01277 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Berlin, Germany, 14050 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Duisburg, Germany, 47199 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krefeld, Germany, 47798 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bitterfeld, Germany, 06749 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamburg, Germany, 22177 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hohenau, Germany, 94545 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Boscastle, United Kingdom, PL35 0BG | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ely, United Kingdom, CB7 5SQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sheffield, United Kingdom, S7 2DW | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Motherwell, United Kingdom, ML1 3JX | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site St Austell, United Kingdom, PL26 7RL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ely, United Kingdom, CB7 4HF | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Slough, United Kingdom, SL1 1TT | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Cardiff, United Kingdom, CF5 4AD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS25 1AN | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Peterborough, United Kingdom, PE7 3JL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamilton, United Kingdom, ML3 ODR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Darlington, United Kingdom, DL2 1AA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Thedinghausen, Germany, 27321 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Nienburg, Germany, 31582 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ettlingen, Germany, 78275 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Northeim, Germany, 37154 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Aurich, Germany, 26603 | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Daaden, Germany, 57567 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Riede, Germany, 27339 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chipping Norton, United Kingdom, OX75FA | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Crawley, United Kingdom, RH10 7DX | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Wishaw, United Kingdom, ML2 7BQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sandbach, United Kingdom, CW11 1EQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS25 7AB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Peterborough, United Kingdom, PE8 6PL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wymondham, United Kingdom, NR18 0RF | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bath, United Kingdom, BA2 4BY | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Penzance, United Kingdom, TR18 4EL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wellingborough, United Kingdom, NN8 4RW | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Plymouth, United Kingdom, PL6 7TH | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bradford-on-Avon, United Kingdom, BA15 1DQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Fowey, United Kingdom, PL23 1DT | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Chippenham, United Kingdom, SN14 6GT | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Westbury, United Kingdom, BA13 3FQ | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site New Stevenson, United Kingdom, ML1 4LT | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Darlington, United Kingdom, DL3 7JR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bangor, United Kingdom, BT19 1PP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Antrim, United Kingdom, BT36 4PP | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Glasgow, United Kingdom, G21 1TR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Aberdeen, United Kingdom, AB25 2ZD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chestfield, United Kingdom, CT5 3QU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Canterbury, United Kingdom, CT1 3HX | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chesterfield, United Kingdom, S40 4AA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Eccles, United Kingdom, S35 9XQ | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Glasgow, United Kingdom, G20 0XA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site London, United Kingdom, SW12 8EU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Trowbridge, United Kingdom, BA14 9AR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Doncaster, United Kingdom, DN1 2ET | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Coventry, United Kingdom, CV7 8LA | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Leigh-on-Sea, United Kingdom, SS9 2SQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hamilton, United Kingdom, ML3 8AA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Coatbridge, United Kingdom, ML5 3AP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chapelhall, United Kingdom, ML6 8SR | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Hinckley, United Kingdom, LE10 2SE | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hitchin, United Kingdom, SG4 9TH | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site East Horsley, United Kingdom, KT24 6QT | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Blackpool, United Kingdom, FY3 7EN | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Hamilton, United Kingdom, ML3 7EN | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Addlestone, United Kingdom, KT15 2BH | Contact Us: E-mail: [email protected] Phone: Not Available |
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Locations Investigative Site Luton, United Kingdom, LU2 9SB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bury St. Edmunds, United Kingdom, IP32 7EW | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bolton, United Kingdom, BL3 6TL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dronfield, United Kingdom, S18 8QY | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS26 8SZ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bishop Auckland, United Kingdom, DL14 6AB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stowmarket, United Kingdom, IP14 1NL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Inverness, United Kingdom, IV2 4AG | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Irvine, United Kingdom, KA12 0AY | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Blackpool, United Kingdom, FY4 3AD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Peterborough, United Kingdom, PE2 5GP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Antrim, United Kingdom, BT41 3AE | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Tyrone, United Kingdom, BT80 8BG | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Darlington, United Kingdom, DL3 8SQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Whitstable, United Kingdom, CT5 3SE | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rugby, United Kingdom, CV21 3SP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Doncaster, United Kingdom, DN1 2EU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ipswich, United Kingdom, IP4 2PU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS10 3NB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Newcastle Upon Tyne, United Kingdom, NE15 6TQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Coatrbridge, United Kingdom, ML5 3BJ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Carstairs, United Kingdom, ML11 8QD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Thornhill, United Kingdom, DG3 5AA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bolton, United Kingdom, BL5 3UB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Witley Bay, United Kingdom, NE26 1NA | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Craigavon, United Kingdom, BT67 0LQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Newtonabbey, United Kingdom, BT37 9QU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belvidere, United States, 07823 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Taylors, United States, 29687 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Atlanta, United States, 30318 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bury St Edmonds, United Kingdom, IP30 9QU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Tiptree, United Kingdom, CO5 0HB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bellshill, United Kingdom, ML4 1PS | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Brighton, United Kingdom, BN2 1ES | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Glasgow, United Kingdom, G5 0BQ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Johnstone, United Kingdom, PA5 8EY | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Airedire, United Kingdom, ML66DB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Paisley, United Kingdom | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Letchworth, United Kingdom, SG6 4UB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Corsham, United Kingdom, SN3 9DL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belfast, United Kingdom, BT5 7BP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Glasgow, United Kingdom, G52 3QN | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Coventry, United Kingdom, CV6 4DD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Manchester, United Kingdom, M13 9WL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belfast, United Kingdom, BT13 3BW | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Tallahassee Memorial Family Quincy, United States, 32351 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Marianna, United States, 32446-2120 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Tucson, United States, 85712 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Daingerfield, United States, 75638 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Carlisle, United States, 45005-3320 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Clifton, United States, 07013 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Huntington Park, United States, 90255 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Medical Research Centers of South Florida, Inc. Hollywood, United States, 33021 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Broken Bow, United States, 68822 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Carryduff, United Kingdom, BT8 8HR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belfast, United Kingdom, BT1 2JR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belfast, United Kingdom, BT15 2GE | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ballymena, United Kingdom, BT43 6JD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ballymena, United Kingdom, BT42 4JP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Crumlin, United Kingdom, BT29 4LP | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Watford, United Kingdom, WD25 7NL | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bath, United Kingdom, BA1 2SR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dundee, United Kingdom, DD19SY | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hadleigh, United Kingdom, IP7 5DN | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bury St. Edmunds, United Kingdom, IP31 2HD | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS15 9JH | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS25 1HB | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS118BS | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Vernon Hills, United States, 60061 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site San Marcos, United States, 78666 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Montgomery, United States, 45242 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Office of Dr.Larry Levinson, DO Hollywood, United States, 33021 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Jersey City, United States, 07306 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Greensboro, United States, 27401 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Scottsdale, United States, 85260 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rancho Cucamonga, United States, 91730 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rolling Hills Estates, United States, 90274 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Medical Research Trust Boynton Beach, United States, 33426 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Birmingham, United States, 39294 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stratford, United States, 08084 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Leeds, United Kingdom, LS9 9EF | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Forth, United Kingdom, ML1 8AJ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lockerbie, United Kingdom, D11 2BJ | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Crossgar, United Kingdom, BT30 9JU | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Belfast, United Kingdom, BT8 6GR | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kissimmee, United States, 34741 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Port Gibson, United States, 39150 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Prince Frederick, United States, 20678 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sugar Land, United States, 77478 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gainesville, United States, 32601 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hialeah, United States, 33016 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Tampa, United States, 33614 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lockport, United States, 60491 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Evansville, United States, 47713 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lebanon, United States, 40033 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Merit Medical Group, Inc. Richlands, United States, 24641-2067 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Phoenix, United States, 85051 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Duncansville, United States, 16635 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Omaha, United States, 68116-2004 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Helping Hands Clinical Trials Santa Ana, United States, 92704 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lawrenceville, United States, 08648 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Graysville, United States, 35073 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hot Springs, United States, 71913-4457 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rockwall, United States, 75032 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Perrysburg, United States, 43551 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Marion, United States, 43302 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Raleigh, United States, 27609 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Los Angeles, United States, 90025 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Pell City, United States, 35125 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Largo, United States, 33770 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chicago, United States, 60628 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chicago, United States, 60631-1958 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Newark, United States, 19702 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Doylestown, United States, 18901 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site San Antonio, United States, 78205-1116 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Fort Wayne, United States, 46804 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bridgman, United States, 49106 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Interlochen, United States, 49643-9264 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Cadillac, United States, 49601 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Florissant, United States, 63031 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Stephenville, United States, 76401 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Honaker, United States, 24260 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Burlington, United States, 27215 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Cherry Hill, United States, 08084 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Manati, United States, 00674 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Guaynabo, United States, 00968 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Trujilo Alto, United States, 00976 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Skierniewice, Poland, 96-100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Poznan, Poland, 60-539 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sobotka, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lublin, Poland, 20-258 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lodz, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chrzanow, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wloclawek, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Linia, Poland, 84-223 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Katowice, Poland, 40-752 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lublin, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Linden, United States, 07036 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations PharmaTrials, Inc. Perth Amboy, United States, 08861 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site McKinney, United States, 75069 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Panama City, United States, 32401 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Columbus, United States, 28722 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Troy, United States, 48085 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland, 31-567 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Radom, Poland, 26-600 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lancut, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Olkusz, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gdansk, Poland, 80-286 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Skierniewice, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Katowice, Poland, 40-226 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gliwice, Poland, 44-109 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bialystok, Poland, 15-183 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland, 31-637 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Warszawa, Poland, 02-796 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wroclaw, Poland, 51-112 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gdynia, Poland, 81-317 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sellersville, United States, 18960 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Omaha, United States, 68114 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Fremont, United States, 94536-3702 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Hainesport, United States, 08036 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland, 31-156 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Varese, Italy, 21100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Grosseto, Italy, 58100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Torino, Italy, 10023 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bergamo, Italy, 24128 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Orocovis, United States, 00720 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site San Juan, United States, 00918 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site San Juan, United States, 00918 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sopot, Poland, 81-746 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wola, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Czechowice-Dziedzice, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lublin, Poland, 20-044 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Malaszewicze, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bydgoszcz, Poland, 85-863 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Naklo nad Notecia, Poland, 98-100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Grodzisk Mazowiecki, Poland, 05-825 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Amandola, Italy, 63021 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chiavari, Italy, 16043 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Catania, Italy, 95124 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Roma, Italy, 00161 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Roma, Italy, 00157 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Legnano, Italy, 20025 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chieti, Italy, 66100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Asti, Italy, 14100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wejherowo, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Szczyrk, Poland, 43-370 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Warszawa, Poland, 02-507 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bydgoszcz, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Elblag, Poland, 82-300 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Przeworsk, Poland, 37-200 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kutno, Poland, 99-300 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Ostrow Wielkopolski, Poland, 63-400 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Zabrze, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland, 31-011 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wabrzezno, Poland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Barcelona, Spain, 08023 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Barcelona, Spain, 08025 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Murcia, Spain, 30008 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Vic (Barcelona), Spain, 08500 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Murcia, Spain, 30007 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Petrer, Spain, 03610 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Oviedo, Spain, 33013 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Posada de Llanes, Spain, 33594 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Madrid, Spain, 28003 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site León, Spain, 24001 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Krakow, Poland, 30-424 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Warszawa, Poland, 01-192 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gdansk, Poland, 80-822 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gdansk, Poland, 80-461 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Wroclaw, Poland, 50-127 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Malbork, Poland, 82-200 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Oviedo, Spain, 33009 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Lugo, Spain, 27770 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site León, Spain | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Viveiro, Spain, 27850 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Madrid, Spain, 28032 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Orense, Spain, 32003 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Elche, Spain | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Novara, Italy, 28100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Reggio Emilia, Italy, 42019 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Foggia, Italy, 71100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Chieri, Italy, 10023 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Reggio Emilia, Italy, 42123 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Moncalieri, Italy, 10024 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Como, Italy, 22066 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Napoli, Italy, 80131 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Badajoz, Spain, 06140 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site La Victoria, Spain, 38380 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gümar, Spain, 38591 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Benidorm, Spain, 03503 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Enniscorthy, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Cork, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Alcover, Spain, 43460 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Begonte, Spain, 27373 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Murcia, Spain, 300005 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Kilmallock, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Tallow, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Dublin, Ireland, 2 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Espinardo, Spain, 30100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Xixona, Spain, 03100 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Alicante, Spain, 03007 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Albacete, Spain, 2260 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Huelva, Spain, 21003 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Barcelona, Spain, 08017 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Salamanca, Spain, 27-31 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Sobrado dos Monxes, Spain, 15813 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Valladolid, Spain, 47007 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Santander, Spain, 39009 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Madrid, Spain, 28030 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site La Roda, Spain, 06230 | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Gorey, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bray, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Rathkeale, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Locations Investigative Site Bishopstown, Ireland | Contact Us: E-mail: [email protected] Phone: Not Available |
Trial Design
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center, Parallel Group Study to Assess the Efficacy (Reduction of Cardiovascular Disease Events) and Safety of 100 mg Enteric-Coated Acetylsalicylic Acid in Patients at Moderate Risk of Cardiovascular Disease
Trial Type:
Interventional
Intervention Type:
Drug
Trial Purpose:
Prevention
Allocation:
Randomized
Blinding:
Double Blind
Assignment:
Parallel Assignment
Trial Arms:
2
Primary Outcome
- Time to the first occurrence of the composite outcome of MI (myocardial infarction), stroke, cardiovascular death, UA (unstable angina) or TIA (transient ischemic attack)The primary efficacy endpoint was a composite outcome consisting of the first occurrence of confirmed MI, stroke, cardiovascular death, UA, TIA. The time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses.Timeframe: Until follow-up (approximate 6 years)
Secondary Outcome
- Time to the first occurrence of the composite outcome of cardiovascular death, MI, or stroke (ischemic, hemorrhagic, or unknown)The time to Composite outcome consisting of the first occurrence of cardiovascular death, MI, or stroke (ischemic, hemorrhagic, or unknown) was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses.Timeframe: Until follow-up (approximate 6 years)
- Time to the first occurrence of the individual components of the primary: non-fatal MI, total MI, non-fatal stroke, total stroke, cardiovascular death, UA and TIAThe time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses.Timeframe: Until follow-up (approximately 6 years)
- Time to all-cause mortality, the first occurrence of all cancers excluding non-melanoma skin cancer (NMSC) and the first occurrence of colon cancerThe time to event was defined as the number of days from the date of randomization to the date of the event confirmed by adjudication. The numbers of days for milestones when 1%, 2%, 3% and 4% of the subjects have reached endpoint events were estimated from Kaplan-Meier-Analyses.Timeframe: Until follow-up (approximately 6 years)
- Incidence of all-cause mortality, all cancers excluding non-melanoma skin cancer and colon cancerTimeframe: Until follow-up (approximately 6 years)
- Incidence of confirmed MI, stroke, cardiovascular death, UA, and TIA separatelyThe percentages of subjects with the efficacy endpoints of confirmed MI, stroke, cardiovascular death, UA and TIA are reported separately.Timeframe: Until follow-up (approximately 6 years)
Additional Information
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