Trial Condition(s):

Chronic Bronchitis

Moxifloxacin versus amoxicillin clavulanic acid in treatment of acute exacerbation of chronic bronchitis

Bayer Identifier:

11980

ClinicalTrials.gov Identifier:

NCT00656747

EudraCT Number:

2007-006096-37

Study Completed

Trial Purpose

A study to assess the safety and efficacy of moxifloxacin compared to that of amoxicillin-clavulanic acid for the treatment of subjects with acute exacerbation of chronic bronchitis.

Inclusion Criteria
- Outpatients with chronic bronchitis
 - Male or female subjects, >=60 years old
 - Post bronchodilator forced expiratory volume in one second (FEV1) less than or equal to 60% predicted and FEV1 / forced vital capacity (FVC) less than 70% at enrollment
 - Documented history of 2 or more AECB episodes, within 12 months of study enrollment, requiring a course of systemic antibiotics and/or systemic corticosteroids
 - All symptoms/signs must be present and confirmed by the Investigator:
 -- increase in dyspnea
 -- purulent sputum
 -- increase in sputum volume
 - Current or past cigarette smoker with equal to or greater than 20 pack year smoking history
 - Subjects must be exacerbation free for at least 30 days prior to enrollment
 - Subjects must be willing and able to complete the questionnaires and subject booklet without assistance
Exclusion Criteria
- Known hypersensitivity to quinolones, ß lactams, or to any of the excipients of the study drugs
 - Known to have congenital or acquired QT prolongation
 - Known to have clinically relevant bradycardia
 - Known to have clinically relevant heart failure with reduced left ventricular ejection fraction
 - Known to have previous history of symptomatic arrhythmias
 - Taking QT prolonging drugs, for example Class Ia or III antiarrhythmic agents or other QT prolonging drugs
 - Known electrolyte disturbances that are not controlled, particularly uncorrected hypokalemia
 - Known history of hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose galactose malabsorption
 - History of a tendon disease/disorder 
 - Known history of liver dysfunction (Child-Pugh C), including known elevated transaminase levels (alanine aminotransferase [ALT] and/or aspartate aminotransferase [AST] >5 times the upper limit of normal [5 x ULN])
 - Known severe renal impairment with glomerular filtration rate of <30 mL/min
 - Known neutropenia (neutrophil count <1000/mm3) caused by immunosuppressive therapy or malignancy
 - Known to have Acquired Immunodeficiency Syndrome (AIDS) (CD4 count of <200/mm3), or be human immunodeficiency virus (HIV) positive and receiving highly active anti retroviral therapy (HAART) (testing for HIV is not mandatory)
 - Known chronic asthma (>15% reversibility or at least 200 mL), bronchial carcinoma, active pulmonary tuberculosis, known diffuse bronchiectasis, cystic fibrosis, or pneumonia (a chest x ray is not mandatory)
 - Known history of chronic colonization of pathogenic organisms resistant to moxifloxacin and/or amoxicillin clavulanic acid (eg, P. aeruginosa, methicillin resistant Staphylococcus aureus)
 - Receiving long term (>4 consecutive weeks) systemic corticosteroid treatment (>10 mg/day of prednisolone or equivalent)
 - Received short course of systemic corticosteroid treatment within 30 days prior to enrollment
 - Life expectancy of less than 6 months
 - Receiving systemic antibacterial therapy within 30 days prior to study enrollment
 - Requiring concomitant systemic antibacterial agents
 - Requiring home ventilatory support (subjects requiring home/portable oxygen therapy or continuous positive airway pressure (CPAP) for sleep apnea are not excluded) and/or those who have a tracheotomy in situ 
 - History of liver function disorders following previous treatment with amoxicillin-clavulanic acid
 - Receiving disulfiram therapy

Trial Summary

Enrollment Goal
1372
Trial Dates
black-arrow
Phase
4
Could I receive a placebo?
No
Products
Avelox (Moxifloxacin hydrochloride, BAY12-8039)
Accepts Healthy Volunteers
No

Where to Participate

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Locations
Status
LocationsStatus
Locations

Praxis Hr. Dr. A. Colberg

Bad Segeberg, Germany, 23795

Status
Completed
 
Locations

Praxis Hr. Dr. R. Gebhardt

Berlin, Germany, 12043

Status
Terminated
 
Locations

Ambulantes Zentrum für Lungenkrankheiten

Cottbus, Germany, 03050

Status
Completed
 
Locations

Praxis Hr. Dr. Th. Schultz

Berlin, Germany, 12203

Status
Completed
 
Locations

Praxis Hr. Dr. G. Hoheisel

Leipzig, Germany, 04275

Status
Terminated
 
Locations

Praxis Drs. Laumen/Wiederhold

Fulda, Germany, 36039

Status
Completed
 
Locations

Praxis Hr. Dr. M. Huntemann

Lüdenscheid, Germany, 58515

Status
Completed
 
Locations

Gemeinschaftspraxis Innere Medizin

Augsburg, Germany, 86150

Status
Terminated
 
Locations

Praxis Fr. Dr. K. Todoroff

Bad Dürrheim, Germany, 78073

Status
Completed
 
Locations

Praxis Hr. Dr. J. C. Becker

Lübeck, Germany, 23552

Status
Completed
 
Locations

Gemeinschaftspraxis & Zentrum

Frankfurt, Germany, 60318

Status
Terminated
 
Locations

Praxis Fr. Dr. K. Böhm

Neubrandenburg, Germany, 17033

Status
Terminated
 
Locations

Praxis Hr. Dr. C. Geßner

Leipzig, Germany, 04357

Status
Completed
 
Locations

Praxis Drs.Deckelmann/Eckhardt

Leipzig, Germany, 04207

Status
Completed
 
Locations

Praxis Hr. Dr. J. Hampf

Meißen, Germany, 01662

Status
Terminated
 
Locations

Praxis fü Lungen- und Bronchialheilkunde,

Berlin, Germany, 10717

Status
Completed
 
Locations

IFG Institut für Gesundheitsförderung GmbH

Rüdersdorf, Germany, 15562

Status
Terminated
 
Locations

Praxis Hr. Dr. M. Raffenberg

Zossen, Germany, 15806

Status
Completed
 
Locations

Praxis Drs. Westerhausen/Pettenkofer/Klüppelberg

Berlin, Germany, 10969

Status
Completed
 
Locations

Gemeinschaftspraxis Drs. Hartjen, Sostmann, Timmermann

Hamburg, Germany, 20354

Status
Completed
 
Locations

Medizinisches AllergoPneumologisches Versorgungszentrum

Dresden, Germany, 01307

Status
Completed
 
Locations

Praxis Hr. Dr. A. de Roux

Berlin, Germany, 14059

Status
Completed
 
Locations

Praxis Hr. Dr. J. Groth

Neuwied, Germany, 56564

Status
Terminated
 
Locations

Medizinsches Versorgungszentrum Delitzsch

Delitzsch, Germany, 04509

Status
Completed
 
Locations

Praxis Hr. Dr. J. Eller

Berlin, Germany, 13597

Status
Terminated
 
Locations

Gemeinschaftspraxis Dr. Grützmacher / Dr. tenHoff

Hamburg, Germany, 22305

Status
Terminated
 
Locations

Praxis Hr. Dr. H.-H. Ponitz / Hr. Dr. G. Hoppe

Berlin, Germany, 10365

Status
Terminated
 
Locations

Praxis Hr. Dr. A. Schwittay

Böhlen, Germany, 04564

Status
Completed
 
Locations

Baillieston Health Centre

Glasgow, United Kingdom, G69 7AD

Status
Completed
 
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Centre d'allergologie et de pneumologie respiratoire

PERPIGNAN, France, 66025

Status
Terminated
 
Locations

Ospedale San Giuseppe FbF Polo Universitario

Milano, Italy, 20123

Status
Terminated
 
Locations

A.O. Sacco Polo Universitario

Milano, Italy, 20157

Status
Terminated
 
Locations

A.O. di Perugia

Perugia, Italy, 06156

Status
Terminated
 
Locations

ASL Salerno - Campania

Pregiato di Cava dei Tirreni, Italy, 84013

Status
Completed
 
Locations

AULSS 22 Bussolengo - Veneto

Bussolengo, Italy, 37012

Status
Terminated
 
Locations

Hospital Clínico Universitario San Carlos

Madrid, Spain, 28040

Status
Terminated
 
Locations

Hospital General de Requena

Requena, Spain, 46340

Status
Completed
 
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Scimed Research, Inc.

Kelowna, Canada, V1Y 8E7

Status
Completed
 
Locations

Antigonish Clinical Trials

Antigonish, Canada, B2G 2C2

Status
Completed
 
Locations

CHUM - Hopital Notre-Dame

Montreal, Canada, H2L 4M1

Status
Completed
 
Locations

Q & T Research, Inc.

Sherbrooke, Canada, JIH 4J6

Status
Terminated
 
Locations

University of Calgary

Calgary, Canada, T2N 4Z6

Status
Completed
 
Locations

St.Joseph's Health Care-London

London, Canada, N6A 4V2

Status
Terminated
 
Locations

Anderston Medical Centre

Glasgow, United Kingdom, G3 8YJ

Status
Terminated
 
Locations

Park Leys Medical Practice

Coventry, United Kingdom, CV7 8LA

Status
Terminated
 
Locations

The Surgery

Glasgow, United Kingdom

Status
Terminated
 
Locations

Thornliebank Health Centre

Glasgow, United Kingdom, G46 8NY

Status
Completed
 
Locations

Castlemilk Health Centre

Glasgow, United Kingdom, G45 9AW

Status
Completed
 
Locations

Cabinet médical - Cronstadt - Nice

NICE, France, 06000

Status
Terminated
 
Locations

Cabinet Médical - Morgiou - Marseille

MARSEILLE, France, 13009

Status
Terminated
 
Locations

Cabinet Médical - Martinon - Mont de Marsan

MONT-DE-MARSAN, France, 40000

Status
Terminated
 
Locations

AUSL 2 Lanciano-Vasto-Chieti - Abruzzo

Chieti, Italy, 66100

Status
Completed
 
Locations

ASUR Marche ZT13 Ascoli Piceno

Ascoli Piceno, Italy, 63100

Status
Completed
 
Locations

A.O. Ospedale Circolo Busto Arsizio

Busto Arsizio , Italy, 21052

Status
Completed
 
Locations

ARNAS Garibaldi

Catania, Italy, 95122

Status
Terminated
 
Locations

Hospital Universitari Germans Trias i Pujol

Badalona, Spain, 08916

Status
Completed
 
Locations

Hospital Universitari Son Espases

Palma de Mallorca, Spain, 07010

Status
Completed
 
Locations

Hospital General Universitario de Guadalajara

Guadalajara, Spain, 19002

Status
Terminated
 
Locations

St. Joseph's Healthcare - Hamilton

Hamilton, Canada, L8N 4A6

Status
Terminated
 
Locations

Medical Clinic

Sydney Mines, Canada, B1V 2Y5

Status
Completed
 
Locations

Grey Nun's Community Hospital

Edmonton, Canada, T6L 5X8

Status
Completed
 
Locations

Health Science Centre

Winnipeg, Canada, R3A 1R8

Status
Terminated
 
Locations

Primary Care Lung Clinic

Toronto, Canada, M6H 3M2

Status
Terminated
 
Locations

Office of Dr.Robert Luton, MD

London, Canada, N6A 5G6

Status
Completed
 
Locations

Clinique Invascor Inc.

Longueuil, Canada, J4N 1E1

Status
Terminated
 
Locations

JBN Medical Diagnostic Services, Inc.

Burlington, Canada, L7R 3X4

Status
Completed
 
Locations

CU de Mont-Godinne

YVOIR, Belgium, 5530

Status
Terminated
 
Locations

Dr. Vereecken

HALEN, Belgium, 3545

Status
Completed
 
Locations

Catharina

EINDHOVEN, Netherlands, 5623 EJ

Status
Completed
 
Locations

Diaconessenhuis Meppel

MEPPEL, Netherlands, 7943 KA

Status
Terminated
 
Locations

Diakonessenhuis

UTRECHT, Netherlands, 3582 KE

Status
Terminated
 
Locations

Hospital Central Universitario

Chihuahua, Mexico, 31350

Status
Completed
 
Locations

Antiguo Hospital Civil de Guadalajara "Fray Antonio Alcalde"

Guadalajara, Mexico, 44280

Status
Completed
 
Locations

Centro Médico de las Américas

Mérida, Mexico, 97001

Status
Terminated
 
Locations

Hospital General del Parc Sanitari de Sant Joan de Déu

Sant Boi de Llobregat, Spain, 08830

Status
Completed
 
Locations

CAP Sarrià

Barcelona, Spain, 08034

Status
Completed
 
Locations

Consorci d’Atenció Primària de Salut de l’Eixample

Barcelona, Spain, 08036

Status
Completed
 
Locations

Office of Dr. Tharwat Fera, MD

Vancouver, Canada, V5Z 4E1

Status
Completed
 
Locations

Winnipeg Clinic

Winnipeg, Canada, R3C 0N2

Status
Completed
 
Locations

University of Alberta

Edmonton, Canada, T6G 2B7

Status
Completed
 
Locations

Office of Dr. Graham W. Bishop, MD

Saint John, Canada, E2M 3W5

Status
Terminated
 
Locations

Office of Dr. Brian Craig, MD

Saint John, Canada, E2K 2T8

Status
Terminated
 
Locations

Algemeen Stedelijk Ziekenhuis Campus Aalst

AALST, Belgium, 9300

Status
Completed
 
Locations

Sint-Vincentiusziekenhuis Campus Sint-Vincentiusziekenhuis

ANTWERPEN, Belgium, 2018

Status
Terminated
 
Locations

Dr. MARTINOT Jean-Benoît

NAMUR, Belgium, 5000

Status
Completed
 
Locations

CHU Brugmann/UVC Brugmann

BRUXELLES - BRUSSEL, Belgium, 1020

Status
Terminated
 
Locations

Dr. Hutsebaut

MOERKERKE, Belgium, 8340

Status
Terminated
 
Locations

Dr. Huysmans

LOMMEL, Belgium, 3920

Status
Terminated
 
Locations

Atrium Medisch Centrum Parkstad

HEERLEN, Netherlands, 6419 PC

Status
Completed
 
Locations

Spaarne Ziekenhuis

HOOFDDORP, Netherlands, 2134 TM

Status
Terminated
 
Locations

Hospital Ángeles Lomas

Huixquilucan, Mexico, CP 52763

Status
Terminated
 
Locations

Hospital San Agustín Zacatecas

Zacatecas, Mexico, 98608

Status
Completed
 
Locations

Worthwhile Clinical Trials

Benoni, South Africa, 1500

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Completed
 
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Paarl Research Centre

Paarl, South Africa, 7647

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Completed
 
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Clinresco Kempton Park

Kempton Park, South Africa, 1610

Status
Completed
 
Locations

I. Engelbrecht Reseach (Pty) Ltd

Centurion, South Africa, 0140

Status
Completed
 
Locations

University of Stellenbosch

Cape Town, South Africa, 7505

Status
Completed
 
Locations

Vergelegen Medi-Clinic

Somerset West, South Africa, 7130

Status
Completed
 
Locations

Emmed Research

Pretoria, South Africa, 0084

Status
Completed
 
Locations

Intercare Medical & Dental Centre Glenfair

Pretoria, South Africa

Status
Completed
 
Locations

sunnyside Mediclinic

Pretoria, South Africa, 0002

Status
Terminated
 
Locations

Newkwa Medical Centre

Durban, South Africa, 4037

Status
Completed
 
Locations

Clinic of pulmonary diseases

Neratovice, Czech Republic, 227 11

Status
Completed
 
Locations

Hospital Kyjov

Kyjov, Czech Republic, 697 01

Status
Terminated
 
Locations

SPIiN

Praha - Troja, Czech Republic, 182 00

Status
Completed
 
Locations

Hospital Metropolitano "Dr. Bernardo Sepúlveda"

Monterrey, Mexico, 66480

Status
Terminated
 
Locations

Hospital General O'Horán SS

Mérida, Mexico, 97001

Status
Completed
 
Locations

Unidad de Investigación Clínica en Medicina

Monterrey, Mexico, 64718

Status
Completed
 
Locations

Josha Research

Bloemfontein, South Africa, 9324

Status
Completed
 
Locations

Randles Road Medical Centre

Durban, South Africa, 4091

Status
Completed
 
Locations

Park Medical Centre

Witbank, South Africa, 1035

Status
Completed
 
Locations

Tambotie Medical Centre

Thabazimbi, South Africa, 0380

Status
Completed
 
Locations

Mercantile Hospital Centre

Port Elizabeth, South Africa, 6014

Status
Completed
 
Locations

Clinic of pulmonary diseases

Praha - Malesice, Czech Republic, 108 00

Status
Completed
 
Locations

Clinic of pulmonary diseases and internal medicine

Lovosice, Czech Republic, 410 02

Status
Completed
 
Locations

Sir Charles Gairdner Hospital

Nedlands, Australia, 6009

Status
Completed
 
Locations

Repatriation General Hospital

Adelaide, Australia, 5041

Status
Completed
 
Locations

Concord Repatriation General Hospital

Concord, Australia, 2139

Status
Terminated
 
Locations

Centro Hospitalar de Lisboa Ocidental-Hospital Santa Marta

Lisboa, Portugal, 1169-024

Status
Terminated
 
Locations

Centro Hospitalar Vila Nova de Gaia

Vila Nova de Gaia, Portugal, 4434-502

Status
Terminated
 
Locations

Clinic of pulmonary diseases

Pardubice - Trnova, Czech Republic, 530 09

Status
Completed
 
Locations

Queen Elizabeth Hospital

Woodville, Australia, 5011

Status
Completed
 
Locations

Brisbane Mater Misericordiae Hospital

Brisbane, Australia, 4101

Status
Completed
 
Locations

Centro Hospitalar Torres Vedras.H.Dr José Maria Antunes Jr

Torres Vedras, Portugal, 2560-324

Status
Terminated
 
Locations

Hospital de Santarém

Santarém, Portugal, 2005-177

Status
Terminated
 
Locations

Hospital Pedro Hispano

Matosinhos, Portugal, 4454-509

Status
Terminated
 
Locations

Instituto Médico de Asistencia e Investigación

Buenos Aires, Argentina, C1425AWC

Status
Completed
 
Locations

Hospital Militar Central "CIR. MY. C. Argerich"

Buenos Aires, Argentina, 1426

Status
Completed
 
Locations

Centro Respiratorio Quilmes

Quilmes, Argentina

Status
Completed
 
Locations

Investigaciones en Patologías Respiratorias

San Miguel de Tucumán, Argentina

Status
Completed
 
Locations

Inst. de Dermatología y Neumonología "Dr. Carlos Luna"

Buenos Aires, Argentina

Status
Completed
 
Locations

Centro Médico Dra. De Salvo - Clinical Research Center

Buenos Aires, Argentina, 1426

Status
Completed
 
Locations

Hospital Carlos van Buren

Valparaíso, Chile

Status
Completed
 
Locations

Hospital Nacional del Tórax

Santiago , Chile

Status
Completed
 
Locations

Clínica Ciudad del Mar

Viña del Mar, Chile

Status
Completed
 
Locations

Centro Hospitalar Coimbra

S. Martinho do Bispo, Portugal, 3041-856

Status
Completed
 
Locations

Centro Hospitalar de Lisboa Norte - Hospital Santa Maria

Lisboa, Portugal, 1649-035

Status
Terminated
 
Locations

Hospitais da Universidade de Coimbra

Coimbra, Portugal, 3000-075

Status
Terminated
 
Locations

Hospital de São João

Porto, Portugal, 4200

Status
Terminated
 
Locations

Hospital Zonal de Agudos Dr. Antonio Cetrángolo

Vicente López, Argentina, 1638

Status
Completed
 
Locations

Fund. Asistencia e Inv. Clínica en Enferm. Prevalentes

Buenos Aires, Argentina

Status
Terminated
 
Locations

Hospital Centro de Salud Zenon Santillan

San Miguel de Tucumán, Argentina, 4000

Status
Completed
 
Locations

Centro de Investigaciones Médicas

Florencio Varela, Argentina

Status
Completed
 
Locations

Clínica del Sol

Buenos Aires, Argentina

Status
Completed
 
Locations

Centro de Enfermedades Respiratorias

Buenos Aires, Argentina, C1424BSF

Status
Completed
 
Locations

Hospital Gustavo Fricke

Viña del Mar, Chile

Status
Completed
 
Locations

Hospital Militar Central

Santafe de Bogotá, Colombia

Status
Completed
 
Locations

Centro Médico Imbanaco

Cali, Colombia

Status
Completed
 
Locations

Instituto Neumológico de Oriente

Bucaramanga, Colombia

Status
Terminated
 
Locations

Clínica Soma

Medellín, Colombia

Status
Completed
 
Locations

Clinica Avansalud

Santiago, Chile

Status
Completed
 
Locations

NeumoInvestigaciones

Bogotá, Colombia

Status
Completed
 
Locations

Fundación Neumológica Colombiana

Bogotá, Colombia

Status
Terminated
 
Locations

Hospital San Vicente de Paul

Medellín, Colombia

Status
Completed
 
Locations

Fundación Clínica Valle del Lili

Cali, Colombia

Status
Terminated
 
Locations

Clínica Medellín

Medellín, Colombia

Status
Completed
 
Locations

University General Hospital of Patras

Rio , Greece, 265 04

Status
Completed
 
Locations

University General Hospital of Larissa

Mezourlo, Greece, 41110

Status
Completed
 
Locations

Evangelismos General Hospital of Athens

Athens, Greece, 106 76

Status
Completed
 
Locations

Pontificia Universidade Católica do RS - Centro Clínico

Porto Alegre, Brazil, 90610-000

Status
Completed
 
Locations

Universidade Federal de Juiz de Fora- Hospital Universitario

Juiz de Fora, Brazil, 36036-110

Status
Completed
 
Locations

Hospital das Clínicas da Faculdade de Medicina da USP

São Paulo, Brazil, 05403-900

Status
Completed
 
Locations

first affiliated hospital of guangzhou medical college

Guangzhou, China, 510120

Status
Completed
 
Locations

West China Hospital, Sichuan University

Chengdu, China, 610041

Status
Completed
 
Locations

Centro de Investigación Clínica FOQUS

Bogotá, Colombia

Status
Completed
 
Locations

Sotiria General State Hospital of Chest Diseases

Athens, Greece, 11527

Status
Completed
 
Locations

General University Hospital of Ioannina

Ioannina, Greece, 45500

Status
Completed
 
Locations

UNIFESP/EPM

São Paulo, Brazil, 04032-060

Status
Completed
 
Locations

Shanghai Changzheng Hospital

Shanghai, China, 200003

Status
Completed
 
Locations

Respiratory Diseases Institute, Beijing Chaoyang Hospital

Beijing, China, 100020

Status
Completed
 
Locations

Shengjing Hosp. of China Medical Univ.

Shengyang, China, 110004

Status
Completed
 
Locations

1st Affiliated Hosp., Guangzhou Univ. TCM

Guangzhou, China, 510405

Status
Completed
 
Locations

Dr Soetomo Hospital

Surabaya, Indonesia

Status
Completed
 
Locations

Vilnius region outpatient department

Vilnius, Lithuania, LT-06122

Status
Completed
 
Locations

Saules family medicine center

Kaunas, Lithuania, LT-50425

Status
Completed
 
Locations

Silainiu family health center

Kaunas, Lithuania

Status
Completed
 
Locations

Praxis Dr. U. Honegger

Zürich, Switzerland, 8048

Status
Terminated
 
Locations

Praxis Hr. Dr. T. Toth

Thun, Switzerland, 3600

Status
Terminated
 
Locations

The 6th People's Hospital of Shanghai Jiao Tong University

Shanghai, China, 200233

Status
Completed
 
Locations

Shanghai Huadong Hospital

Shanghai, China, 200040

Status
Completed
 
Locations

General Hospital, Tianjin Medical University

Tianjin, China, 300052

Status
Completed
 
Locations

Beijing Friendship Hosp.

Beijing, China, 100050

Status
Completed
 
Locations

The First hospital of China Medical University

Shenyang, China, 110001

Status
Completed
 
Locations

The Third Xiangya Hospital of Central South University

Changsha, China, 410013

Status
Completed
 
Locations

Persahabatan Hospital

Jakarta , Indonesia, 13230

Status
Completed
 
Locations

Immanuel Hospital

Bandung, Indonesia

Status
Completed
 
Locations

Seskines outpatient clinic

Vilnius, Lithuania, LT-07156

Status
Terminated
 
Locations

UAB "Mano seimos gydytojas"

Klaipeda, Lithuania, LT-94231

Status
Completed
 
Locations

Siauliai County Hospital

Siauliai, Lithuania, 76231

Status
Completed
 
Locations

Praxis Hr. Dr. R. Siebenschein

Wettingen, Switzerland, 5430

Status
Terminated
 
Locations

Universitätsspital Basel

Basel, Switzerland, 4031

Status
Completed
 
Locations

Praxis Dr. med. P. Ruff

Oberwil, Switzerland, 4104

Status
Terminated
 
Locations

Praxis Dr. med. Martin Anton Tschan

Laufen, Switzerland, 4242

Status
Terminated
 
Locations

Spital Netz Bern Spital Tiefenau

Bern, Switzerland, 3004

Status
Terminated
 
Locations

Lungenpraxis Aarau

Aarau, Switzerland, 5000

Status
Terminated
 
Locations

Praxis Dr. med. Alexander Haegeli

Binningen, Switzerland, 4102

Status
Terminated
 
Locations

Universitätsspital Zürich

Zürich, Switzerland, 8091

Status
Terminated
 
Locations

Clínica San Pablo

Lima, Peru, 33

Status
Completed
 
Locations

Hospital Alberto Sabogal Sologuren

Callao, Peru, CALLAO 2

Status
Terminated
 
Locations

Hospital Central de la Fuerza Aerea del Perú

Lima, Peru, LIMA 18

Status
Completed
 
Locations

Clínica Internacional

Lima, Peru

Status
Completed
 
Locations

Hospital Nacional Cayetano Heredia

Lima, Peru, 31

Status
Completed
 
Locations

Tuen Mun Hospital

HongKong, Hong Kong, China

Status
Completed
 
Locations

Manila Doctors Hospital

Manila, Philippines

Status
Completed
 
Locations

Lung Center of the Philippines

Quezon City, Philippines

Status
Completed
 
Locations

Latvian Postdiploma Education Institute Ambulatory part

Riga, Latvia, 1011

Status
Terminated
 
Locations

Dr E Tirans Private Practice

Riga, Latvia, 1009

Status
Terminated
 
Locations

Dr Harasimjukas private practice

Valmiera, Latvia, 4201

Status
Terminated
 
Locations

Ltd "BINI" (SIA "BINI")

Ventspils, Latvia, LV-3601

Status
Completed
 
Locations

Klinika za plucne bolesti Jordanovac

Zagreb, Croatia, 10000

Status
Completed
 
Locations

Clínica El Golf

Lima, Peru, LIMA 27

Status
Completed
 
Locations

Princess Margaret Hospital

Kowloon, Hong Kong, China

Status
Completed
 
Locations

Chest Disease Institute

Nonthaburi , Thailand, 11000

Status
Completed
 
Locations

Maharaj Nakorn Chiang Mai Hospital

Chiang Mai , Thailand, 50200

Status
Completed
 
Locations

King Chulalongkorn Memorial Hospital

Bangkok, Thailand, 10330

Status
Completed
 
Locations

Hospital Ntra. Sra. de Meritxell

Escaldes - Engordany, Andorra

Status
Completed
 
Locations

Gimenes Arstu prakse

Riga, Latvia, 1050

Status
Completed
 
Locations

SIA Talsi veselibas centrer

Talsu, Latvia, 3201

Status
Completed
 
Locations

Kraslavas hospital

Kraslava, Latvia, 5601

Status
Completed
 
Locations

KBC Rijeka

Rijeka, Croatia, 510 00

Status
Completed
 
Locations

OB dr. Ivo Pedisic

Petrinja, Croatia, 44 250

Status
Completed
 
Locations

Gorey Medical Centre

Gorey, Ireland

Status
Terminated
 
Locations

Farranfore Medical Centre

Killarney, Ireland

Status
Completed
 
Locations

The Palms

Gorey, Ireland

Status
Terminated
 
Locations

Longford Centre

Longford, Ireland

Status
Terminated
 
Locations

Klinika za plucne bolesti Jordanovac

Zagreb, Croatia, 10000

Status
Terminated
 
Locations

KB Osijek

Osijek, Croatia, 310 00

Status
Terminated
 
Locations

Klinicka bolnica Dubrava

Zagreb, Croatia, 10000

Status
Completed
 
Locations

Townhall Clinic

Bray, Ireland

Status
Terminated
 
Locations

Jinnah Postgraduate Medical Centre

Karachi, Pakistan, 75500

Status
Completed
 
Locations

Liaquat National Hospital

Karachi, Pakistan, 74800

Status
Terminated
 
Locations

Shifa International Hospitals Limited

Islamabad, Pakistan

Status
Terminated
 
Locations

Praxis Hr. Dr. C. Keller

Frankfurt, Germany, 60389

Status
Terminated
 
Locations

Slaney Medical Centre

Enniscorthy, Ireland

Status
Completed
 

Trial Design