check_circleStudy Completed
Multiple Sclerosis, Relapsing-Remitting
Bayer Identifier:infoA unique number for a trial given by Bayer.
91656
ClinicalTrials.gov Identifier:infoA unique number for a trial given by United States government.
EudraCT Number:infoA unique reference for a trial given by European medical agency.
EU CT Number:infoA unique reference for a trial given by European medical agency under EU Clinical Trial Regulation
Not Available
BEYOND Follow-up: Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New Dose
Trial purpose
The BEYOND Follow-Up study will give patients who participated in the preceding BEYOND study the opportunity to continue treatment with the 500µg dose of interferon beta (IFNB) 1b and will further investigate the safety and tolerability profile of interferon beta 1b 500µg during longer-term treatment.
Key Participants Requirements
Sex
BothAge
18 - 55 YearsTrial summary
Enrollment Goal info
1420The overall number of participants needed for a trial.
Trial Dates info
May 2007 - March 2008Trial dates are when the trial starts and ends. If they are in the future, then they are estimates and can change before or during a trial.
Phase info
Phase 3A phase is a step in the research of a new treatment.
Could I Receive a placebo info
NoA “placebo” looks like a treatment but usually does not have any real treatment. A placebo is used to make sure the effects of a treatment that are seen in a trial are actually caused by that treatment.
Products info
Betaseron (Interferon beta-1b, BAY86-5046)A “product” can be any kind of drug, medical device, vaccine, or other treatment that is being studied in a trial.
Accepts Healthy Volunteer info
NoA healthy volunteer is a person who takes part in a trial but does not have a disease or condition. Usually, healthy volunteers are in Phase 1 trials.
Where to participate
Status | Institution | Location |
---|---|---|
Completed | Graz, 8036, Austria | |
Withdrawn | Milwaukee, 53215, United States | |
Completed | Tualatin, 97062, United States | |
Completed | Birmingham, 35294-7340, United States | |
Completed | Reno, 89509, United States | |
Completed | Duluth, 55805, United States | |
Withdrawn | St. Louis, 63110, United States | |
Completed | Newark, 07103, United States | |
Completed | Tucson, 85741, United States | |
Completed | Stony Brook, 11794, United States | |
Completed | Detroit, 48202, United States | |
Completed | Albuquerque, 87131-5281, United States | |
Completed | Fort Wayne, 46805, United States | |
Completed | Des Moines, 50314, United States | |
Withdrawn | Augusta, 30912, United States | |
Completed | Sacramento, 95817, United States | |
Completed | Chicago, 60637, United States | |
Completed | Tampa, 33609, United States | |
Completed | Berkeley, 94705, United States | |
Completed | Tampa, 33606, United States | |
Completed | San Francisco, 94117, United States | |
Completed | Rochester, 14642, United States | |
Completed | Mineola, 11501, United States | |
Completed | Nashville, 37205, United States | |
Completed | Durham, 27710, United States | |
Completed | Winston-Salem, 27157, United States | |
Completed | Henderson, 89052, United States | |
Completed | Charlotte, 28207, United States | |
Completed | Seattle, 98101, United States | |
Completed | Washington, 20037, United States | |
Completed | Louisville, 40202, United States | |
Completed | Kansas City, 66160, United States | |
Completed | Philadelphia, 19104, United States | |
Completed | Indianapolis, 46202, United States | |
Completed | San Antonio, 78229, United States | |
Completed | Cullman, 35058, United States | |
Completed | Shreveport, 71130, United States | |
Completed | Columbus, 43210, United States | |
Completed | Houston, 77030, United States | |
Completed | Providence, 02905, United States | |
Completed | Fairfax, 22031, United States | |
Completed | Miami, 33136, United States | |
Completed | Charleston, 29425, United States | |
Completed | Phoenix, 85013, United States | |
Completed | Halifax, B3H 2Y9, Canada | |
Completed | Pittsburgh, 15213, United States | |
Completed | Cincinnati, 45219, United States | |
Completed | La Jolla, 92037, United States | |
Completed | Newark, 19713, United States | |
Completed | Atlanta, 30309-1465, United States | |
Completed | Maitland, 32751, United States | |
Completed | Tacoma, 98405, United States | |
Completed | Fort Collins, 80528, United States | |
Completed | Hull, J8Y 1W7, Canada | |
Completed | Calgary, T2N 2T9, Canada | |
Completed | Vancouver, V6T 2B5, Canada | |
Completed | Nepean, K2G 6E2, Canada | |
Completed | Nimes, 30029, France | |
Completed | nancy, 54035, France | |
Completed | nice, 06000, France | |
Withdrawn | Montreal, H2L 4M1, Canada | |
Completed | Ottawa, K1H 8L6, Canada | |
Completed | Montreal, H3A 2B4, Canada | |
Completed | Toronto, M5B 1W8, Canada | |
Completed | London, N6A 5A5, Canada | |
Completed | Greenfield Park, J4V 2H1, Canada | |
Completed | Mississauga, L5B 1B8, Canada | |
Completed | Lille, 59037, France | |
Completed | Rennes, 35038, France | |
Completed | Dijon, 21033, France | |
Completed | Bordeaux, 33076, France | |
Completed | Nantes, 44093, France | |
Withdrawn | Clermont ferrand, 63003, France | |
Completed | L'Hospitalet de Llobregat, 08907, Spain | |
Completed | Malaga, 29010, Spain | |
Completed | Ospedale San Raffaele | Milano, 20132, Italy |
Terminated | Policlinico Consorziale | Bari, 70122, Italy |
Withdrawn | Toulouse, 31059, France | |
Completed | Sevilla, 41071, Spain | |
Completed | Firenze, 50134, Italy | |
Completed | A.O. di Padova | Padova, 35128, Italy |
Completed | A.O. S.Andrea | Roma, 00189, Italy |
Completed | Athens, 11527, Greece | |
Completed | Uppsala, 751 85, Sweden | |
Completed | Tampere, 33521, Finland | |
Completed | MELSBROEK, 1820, Belgium | |
Completed | Dublin, 9, Ireland | |
Completed | Dublin, 4, Ireland | |
Completed | Cork, Ireland | |
Completed | Dublin, Ireland | |
Completed | Dresden, 01307, Germany | |
Completed | Marburg, 35039, Germany | |
Completed | Hamburg, 20246, Germany | |
Terminated | Ospedale San Luigi Gonzaga | Orbassano, 10043, Italy |
Completed | Thessaloniki, 54636, Greece | |
Completed | Stockholm, 182 88, Sweden | |
Completed | Bergen, N-5021, Norway | |
Completed | Oulu, 90029, Finland | |
Completed | Brussel, 1090, Belgium | |
Completed | Nijmegen, 6533 PA, Netherlands | |
Completed | Sittard, 6131 BK, Netherlands | |
Completed | Breda, 4819 EV, Netherlands | |
Completed | Hannover, 30625, Germany | |
Completed | Greifswald, 17475, Germany | |
Completed | Hennigsdorf, 16761, Germany | |
Completed | Halle, 06120, Germany | |
Completed | Leipzig, 04129, Germany | |
Completed | Berlin, 13347, Germany | |
Completed | Hamburg, 20099, Germany | |
Completed | Heidelberg, 69120, Germany | |
Completed | Düsseldorf, 40225, Germany | |
Completed | Göttingen, 37099, Germany | |
Completed | Offenbach, 63069, Germany | |
Completed | Essen, 45117, Germany | |
Completed | Innsbruck, 6020, Austria | |
Completed | St. Gallen, 9007, Switzerland | |
Completed | Warszawa, 02957, Poland | |
Completed | Gdansk, 80-803, Poland | |
Completed | Katowice, 40752, Poland | |
Completed | Budapest, 1076, Hungary | |
Completed | Pecs, 7623, Hungary | |
Completed | Budapest, 1145, Hungary | |
Completed | Maribor, 2000, Slovenia | |
Completed | Moskva, 127018, Russia | |
Completed | Bayreuth, 95445, Germany | |
Completed | Gießen, 35392, Germany | |
Completed | Berlin, 13585, Germany | |
Completed | Münster, 48149, Germany | |
Completed | Regensburg, 93053, Germany | |
Completed | Hannover, 30559, Germany | |
Completed | Linz, 4020, Austria | |
Completed | St Poelten, A-3100, Austria | |
Completed | Bern, 3010, Switzerland | |
Completed | Wroclaw, 50420, Poland | |
Completed | Lodz, 90153, Poland | |
Completed | Warszawa, 02097, Poland | |
Completed | Poznan, 61848, Poland | |
Completed | Zalaegerszeg-Pozva, H-8900, Hungary | |
Completed | Györ, 9024, Hungary | |
Completed | Miskolc, 3501, Hungary | |
Completed | Ljubljana, SI-1525, Slovenia | |
Completed | Moskva, 118089, Russia | |
Completed | Nizhy Novgorod, 603076, Russia | |
Completed | Kiev, 03110, Ukraine | |
Completed | Riga, LV-1015, Latvia | |
Completed | Jerusalem, 91120, Israel | |
Completed | Tel Hashomer, 52621, Israel | |
Completed | Haifa, 31048, Israel | |
Completed | Ashkelon, 78278, Israel | |
Completed | Zerifin, 70300, Israel | |
Completed | Rosario, S2000ZBL, Argentina | |
Completed | Buenos Aires, C1117ABE, Argentina | |
Completed | Cordoba, X5000HGX, Argentina | |
Completed | Campinas, 13081- 970, Brazil | |
Completed | Sao Paulo, 01221-020, Brazil | |
Completed | Recife, 52010-040, Brazil | |
Completed | Kogarah, 2217, Australia | |
Completed | Moscow, 123367, Russia | |
Completed | Moskva, 117049, Russia | |
Completed | Sankt-Peterburg, 197022, Russia | |
Completed | St. Petersburg, 197376, Russia | |
Completed | Novosibirsk, 630007, Russia | |
Completed | Moskva, 129110, Russia | |
Completed | Yaroslavl, 150000, Russia | |
Completed | St. Petersburg, 194044, Russia | |
Completed | Donetsk, 83003, Ukraine | |
Completed | Kharkiv, 61068, Ukraine | |
Completed | Lviv, 79000, Ukraine | |
Completed | Sourasky Medical Center | Tel-Aviv, 64239, Israel |
Completed | Rosario, Argentina | |
Completed | Buenos Aires, C1416CRJ, Argentina | |
Completed | Buenos Aires, C1280AEB, Argentina | |
Completed | Sao Paulo, 04039-032, Brazil | |
Completed | Sao Paulo, 05403-900, Brazil | |
Completed | Curitiba, 80240-340, Brazil | |
Completed | Rio de Janeiro, 21941-590, Brazil | |
Completed | Porto Alegre, 90035-001, Brazil | |
Completed | Wyoming, NSW 2250, Australia | |
Completed | Fitzroy, 3065, Australia | |
Completed | Liverpool, NSW 2170, Australia | |
Withdrawn | Nedlands, 6009, Australia | |
Completed | Parkville, 3050, Australia |
Primary OutcomeinfoA primary outcome is the most important effect of a treatment that is measured in a trial. Most trials have one primary outcome measure, but some have more than one.
- Flu-like-syndromedate_rangeTime Frame:309 daysenhanced_encryptionYesSafety Issue:
- Injection-site Reactionsdate_rangeTime Frame:309 daysenhanced_encryptionYesSafety Issue:
- Liver Enzyme Elevationsdate_rangeTime Frame:309 daysenhanced_encryptionYesSafety Issue:
- Hematological Abnormalitiesdate_rangeTime Frame:309 daysenhanced_encryptionYesSafety Issue:
Secondary OutcomeinfoA secondary outcome is an effect of a treatment that is measured in a trial. A secondary outcome is less important than a primary outcome. But secondary outcomes are still important since they help researchers learn more about the effects of a treatment. Most clinical trials have more than one secondary outcome measure.
- Percentage of Patients With Neutralizing Antibody Titer to IFNB-1b of Different Cut-off Valuesdate_rangeTime Frame:309 daysenhanced_encryptionNoSafety Issue:
Trial design
Trial Type info
InterventionalDescribes the nature of the clinical study.
Intervention Type info
DrugAn intervention is a drug, medical device, vaccine, or other treatment that is being studied in a trial or is already approved for all patients to use. An intervention can also include treatments like changing diet and exercise, or educating people about a health topic.
Trial Purpose info
TreatmentThe main reason the clinical trial is being done.
Allocation info
Non-randomizedAllocation is the way treatments are assigned to the people in the trial.
Blinding info
Double Blind“Blinding” means a person in a trial does not know what treatment they are using. Everyone in the trial knows which treatments they might get if they join the trial, but they do not always know which treatment they use during the trial.
Assignment info
Parallel AssignmentAn “assignment” is the way that people in a trial are assigned to use a treatment.
Trial Arms info
3A “trial arm” is a group of people in a trial. Each trial arm is assigned to use a specific treatment. Types of trial arms are: Experimental arm is a group assigned to use the treatment being studied in the trial Active comparator arm is a group assigned to use a treatment considered to be effective. The results of this group are compared to the results of the experimental arm. Placebo arm is a group assigned to use a placebo. A “placebo” looks like a treatment but usually does not have any real treatment. The results of this group are compared to the experimental arm. This helps make sure any effects that are seen in the experimental arm are actually caused by the main treatment being studied. No intervention arm is a group that is not assigned to use a treatment. The people in this group do not use any treatment during the trial.